Catalog No.
RHJ78201
Species reactivity
Human
Host species
Mouse
Isotype
IgG2b
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400
Target
C-type lectin domain family 4 member K, CLEC4K, Langerin, CD207
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9UJ71
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3X41
Langerhans cells infiltration in lymph nodes of patients with systemic lupus erythematosus., PMID:40228845
Langerhans Cell Histiocytosis or Acute Cellular Rejection?, PMID:39497510
Integration of MUTZ-Langerhans cells into a 3D full-thickness skin equivalent and influences of serum reduction and undefined medium supplements on differentiation., PMID:39343070
Immunohistochemistry of the nasal cavity-associated lymphoid tissue in the dolphin (Stenella coeruleoalba, Meyen 1833)., PMID:38683022
Immunohistochemical Characterization of Langerhans Cells in the Skin of Three Amphibian Species., PMID:38666822
Dendritic cell subpopulations in carcinoma ex-pleomorphic adenoma: A multicenter study., PMID:38655689
Deep resolution of clinical, cellular and transcriptomic inflammatory markers of psoriasis over 52 weeks of interleukin-17A inhibition by secukinumab., PMID:38240024
Dengue Virus Infects Human Skin Langerhans Cells through Langerin for Dissemination to Dendritic Cells., PMID:37979773
[Study the involvement of Langerin in mediating epicutaneous sensitization of atopic dermatitis-like mouse model]., PMID:37813655
Emergence of SARS-CoV-2 spike protein at the vaccination site., PMID:36988249
Case report: Targeting the PD-1 receptor and genetic mutations validated in primary histiocytic sarcoma with hemophagocytic lymphohistiocytosis., PMID:36969238
Targeting of SIRPα as a potential therapy for Langerhans cell histiocytosis., PMID:36788737
Confocal Characterization of Intestinal Dendritic Cells from Myxines to Teleosts., PMID:36101424
Imiquimod-induced ex vivo model of psoriatic human skin via interleukin-17A signalling of T cells and Langerhans cells., PMID:36054147
Multi-System Langerhans Cell Histiocytosis as a Mimic of IgG4-Related Disease: A Case Report and Literature Review., PMID:35937835
A subpopulation of green turtle suprabasal epidermal cells are Langerin+ and migrate under in vitro stimulation of the chemokine CCL21., PMID:35098399
Analysis of immune response induction mechanisms implicating the dose-sparing effect of transcutaneous immunization using a self-dissolving microneedle patch., PMID:34998604
Targeted delivery of a vaccine protein to Langerhans cells in the human skin via the C-type lectin receptor Langerin., PMID:34932821
The immune microenvironment of the hydatidiform mole., PMID:34929228
Type 2 immunity plays an essential role for murine model of allergic contact dermatitis with mixed type 1/type 2 immune response., PMID:34763990
Specific Protein Antigen Delivery to Human Langerhans Cells in Intact Skin., PMID:34745102
Targeting human langerin promotes HIV-1 specific humoral immune responses., PMID:34324611
Laser-assisted epicutaneous immunization to target human skin dendritic cells., PMID:33797121
HIV-1 subverts the complement system in semen to enhance viral transmission., PMID:33568786
Proteus mirabilis Targets Atherosclerosis Plaques in Human Coronary Arteries via DC-SIGN (CD209)., PMID:33488579
Identification and expression analysis of Langerhans cells marker Langerin/CD207 in grasscarp, Ctenopharyngodon idella., PMID:33220343
Selective AhR knockout in langerin-expressing cells abates Langerhans cells and polarizes Th2/Tr1 in epicutaneous protein sensitization., PMID:32461368
Reduction in Human Epidermal Langerhans Cells with Age Is Associated with Decline in CXCL14-Mediated Recruitment of CD14+ Monocytes., PMID:31881212
Expression of CD1a, CD207, CD11b, CD11c, CD103, and HLA-DR receptors on the surface of dendritic cells in the skin of patients with atopic dermatitis., PMID:31839771
Expression of Langerin/CD207 in airways, lung and associated lymph nodes of a stranded striped dolphin (Stenella coeruleoalba)., PMID:31784234
Langerhans cells in hypospadias: an analysis of Langerin (CD207) and HLA-DR on epidermal sheets and full thickness skin sections., PMID:31718599
Diabetes Mellitus, Extreme Insulin Resistance, and Hypothalamic-Pituitary Langerhans Cells Histiocytosis., PMID:31341684
Celiac Disease in Children, Particularly with Accompanying Type 1 Diabetes, Is Characterized by Substantial Changes in the Blood Cytokine Balance, Which May Reflect Inflammatory Processes in the Small Intestinal Mucosa., PMID:31214623
A Specific, Glycomimetic Langerin Ligand for Human Langerhans Cell Targeting., PMID:31139717
A Liposomal Platform for Delivery of a Protein Antigen to Langerin-Expressing Cells., PMID:31062587
Intestinal immunity of dogfish Scyliorhinus canicula spiral valve: A histochemical, immunohistochemical and confocal study., PMID:30711492
A high mucosal blocking score is associated with HIV protection., PMID:30703069
[Sorting and identification of human immature Langerhans cells]., PMID:30381119
Claudin-1 expression decreases with increasing pathological grade in actinic keratosis and may be a marker of high-risk actinic keratosis., PMID:30315595
Langerin staining identifies most littoral cell angiomas but not most other splenic angiomatous lesions., PMID:30130631
Toll-like receptor 4 attenuates a murine model of atopic dermatitis through inhibition of langerin-positive DCs migration., PMID:29851146
Langerhans Cells Prevent Autoimmunity via Expansion of Keratinocyte Antigen-Specific Regulatory T Cells., PMID:29307572
Mannose-Binding Lectin Protein Deficiency Among Patients with Primary Immunodeficiency Disease Receiving IVIG Therapy., PMID:29119939
Human Herpesvirus 8 Infects and Replicates in Langerhans Cells and Interstitial Dermal Dendritic Cells and Impairs Their Function., PMID:28768873
Langerhans cell markers CD1a and CD207 are the most rapidly responding genes in lesional psoriatic skin following adalimumab treatment., PMID:28109175
Enhanced Prophylactic and Therapeutic Effects of Polylysine-Modified Ara h 2 DNA Vaccine in a Mouse Model of Peanut Allergy., PMID:28049187
Langerhans cells are predominant high affinity immunoglobulin E receptor bearing cells in the epidermis of bullous pemphigoid skin., PMID:27839901
BRAF V600E mutation correlates with suppressive tumor immune microenvironment and reduced disease-free survival in Langerhans cell histiocytosis., PMID:27622040
The impact of langerin (CD207)+ dendritic cells and FOXP3+ Treg cells in the small bowel mucosa of children with celiac disease and atopic dermatitis in comparison to children with functional gastrointestinal disorders., PMID:27200487
Analysis of the BRAFV600E mutation in 19 cases of Langerhans cell histiocytosis in Japan., PMID:27041734
For research use only. Not for human or drug use.
