Catalog No.
RHJ70201
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400
Target
LRP-1B, LRP-DIT, LRP1B, LRPDIT, Low-density lipoprotein receptor-related protein 1B, Low-density lipoprotein receptor-related protein-deleted in tumor
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9NZR2
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3X10
A Rare Case of a Malignant Proliferating Trichilemmal Tumor: A Molecular Study Harboring Potential Therapeutic Significance and a Review of Literature., PMID:39727620
Antithetical impacts of deleterious LRP1B mutations in non-squamous and squamous NSCLCs on predicting benefits from immune checkpoint inhibitor alone or with chemotherapy over chemotherapy alone: retrospective analyses of the POPLAR/OAK and CHOICE-01 trials., PMID:39276256
Total Neoadjuvant Therapy With PD-1 Blockade for High-Risk Proficient Mismatch Repair Rectal Cancer., PMID:38381429
Multi-omics Analysis Reveals Immune Features Associated with Immunotherapy Benefit in Patients with Squamous Cell Lung Cancer from Phase III Lung-MAP S1400I Trial., PMID:38277235
Genomic characterization of vulvar squamous cell carcinoma reveals differential gene expression based on clinical outcome., PMID:38086165
DNA Mutational Profiling in Patients With Colorectal Cancer Treated With Standard of Care Reveals Differences in Outcome and Racial Distribution of Mutations., PMID:37992266
Profound tumor response to combined CTLA-4 and PD-1 inhibition in systemic fourth line therapy observed in a patient with hepatocellular carcinoma harboring SETD2 and LRP1B mutations., PMID:36379463
Circulating Tumor DNA Identifies Diverse Landscape of Acquired Resistance to Anti-Epidermal Growth Factor Receptor Therapy in Metastatic Colorectal Cancer., PMID:36007218
Profiling of 520 Candidate Genes in 50 Surgically Treated Chinese Small Cell Lung Cancer Patients., PMID:34168983
Prognostic significance of LDL receptor-related protein 1B in patients with gastric cancer., PMID:33389427
Activity of ibrutinib plus R-CHOP in diffuse large B-cell lymphoma: Response, pharmacodynamic, and biomarker analyses of a phase Ib study., PMID:33188997
The combination of camrelizumab and apatinib obtained ongoing partial remission for a patient with osimertinib-resistant non-small cell lung cancer: case report., PMID:33040541
Pembrolizumab in men with heavily treated metastatic castrate-resistant prostate cancer., PMID:31270961
Nuclear localization of LDL receptor-related protein 1B in mammary gland carcinogenesis., PMID:30607440
LRP1b shows restricted expression in human tissues and binds to several extracellular ligands, including fibrinogen and apoE-carrying lipoproteins., PMID:21420681
LRP1B is a negative modulator of increased migration activity of intimal smooth muscle cells from rabbit aortic plaques., PMID:15882972
LRP1B attenuates the migration of smooth muscle cells by reducing membrane localization of urokinase and PDGF receptors., PMID:15166012
For research use only. Not for human or drug use.
