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Anti-IL37/IL1F7 Antibody (R3X03)

Catalog #:   RHJ69502 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: WB
Accession: Q9NZH6
Overview

Catalog No.

RHJ69502

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

WB: 1:500-1:1000

Target

FIL1Z, IL37, Interleukin-1-related protein, IL-23, IL1F7, IL-37, IL1RP1, FIL1 zeta, IL-1X, Interleukin-23, IL-1F7, IL-1RP1, Interleukin-1 family member 7, Interleukin-37, Interleukin-1 homolog 4, Interleukin-1 zeta, IL-1H, IL-1H4, IL-1 zeta, IL1H4

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9NZH6

Applications

WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3X03

Data Image
  • Western blot
    Result: RHJ69502 can detect IL37 by Western blotting.
References

Blockade of IL-1 family cytokines in the treatment of rheumatoid arthritis., PMID:40520203

Pro-inflammatory cytokines in myasthenia gravis: a systematic review and meta-analysis., PMID:40347402

IL-37 protects against house dust mite-induced airway inflammation and airway epithelial barrier dysfunction via inhibiting store-operated calcium entry., PMID:38941668

Immune System Dysregulation in the Progression of Multiple Sclerosis: Molecular Insights and Therapeutic Implications., PMID:38692349

Targeting IL-13 with tralokinumab normalizes type 2 inflammation in atopic dermatitis both early and at 2 years., PMID:38563683

Deep resolution of clinical, cellular and transcriptomic inflammatory markers of psoriasis over 52 weeks of interleukin-17A inhibition by secukinumab., PMID:38240024

Interleukin-37 contributes to endometrial regenerative cell-mediated immunotherapeutic effect on chronic allograft vasculopathy., PMID:38159090

Correlation analysis between cytokines' profile, autoimmune antibodies and the duration of type 1 diabetes: A case control study in a specialized children's centre in Riyadh., PMID:37953627

Vasculitis Activity-Predicting Ability of IL-12 Family Cytokines in Patients with Microscopic Polyangiitis and Granulomatosis with Polyangiitis., PMID:37727919

Selected Immunohistochemical Assessment and Clinical Examinations in the Diagnosis of Palatine Tonsil Diseases., PMID:37445557

Estimation of Interleukin 32 and Interleukin 37 Serum Levels in Iraqi Patients with Rheumatoid Arthritis., PMID:37396740

Interleukin-37 inhibits desmoglein-3 endocytosis and keratinocyte dissociation via upregulation of Caveolin-1 and inhibition of the STAT3 pathway., PMID:37262304

Effect of exogenous IL-37 on immune cells from a patient carrying a potential IL37 loss-of-function variant: A case study., PMID:36476991

Mast Cell Cytokines in Acute and Chronic Gingival Tissue Inflammation: Role of IL-33 and IL-37., PMID:36362030

IL-24 Contributes to Neutrophilic Asthma in an IL-17A-Dependent Manner and Is Suppressed by IL-37., PMID:36174993

The Role of TGFβ and Other Cytokines in Regulating Mast Cell Functions in Allergic Inflammation., PMID:36142776

Anti-inflammatory, antioxidant, anti-fibrotic and schistosomicidal properties of plumbagin in murine schistosomiasis., PMID:36066812

IL-37 alleviates liver granuloma caused by Schistosoma japonicum infection by inducing alternative macrophage activation., PMID:36002836

Expression of LncRNA-BCYRN1 in pediatric asthma and related factors of disease induction., PMID:35818246

Possible association of rotavirus IgG with cytokine expression levels and dyslipidemia in rotavirus-infected type 1 diabetic children., PMID:35733062

Endogenous Levels of Gamma Amino-Butyric Acid Are Correlated to Glutamic-Acid Decarboxylase Antibody Levels in Type 1 Diabetes., PMID:35052771

Subunit-Specific Reactivity of Autoantibodies Against Laminin-332 Reveals Direct Inflammatory Mechanisms on Keratinocytes., PMID:34899732

IL-33, IL-37, and Vitamin D Interaction Mediate Immunomodulation of Inflammation in Degenerating Cartilage., PMID:34842603

Protein engineering of a stable and potent anti-inflammatory IL-37-Fc fusion with enhanced therapeutic potential., PMID:34699747

Cytokine antibody array-based analysis of IL-37 treatment effects in asthma., PMID:34516405

IL-37 Targets TSLP-Primed Basophils to Alleviate Atopic Dermatitis., PMID:34299012

Interleukin-1 Blockade in Polygenic Autoinflammatory Disorders: Where Are We now?, PMID:33708123

Elderly Subjects Supplemented with L-Glutamine Shows an Improvement of Mucosal Immunity in the Upper Airways in Response to Influenza Virus Vaccination., PMID:33572639

IL-35 and IL-37 are negatively correlated with high IgE production among children with asthma in Saudi Arabia., PMID:33492183

Targeting MARCO and IL37R on Immunosuppressive Macrophages in Lung Cancer Blocks Regulatory T Cells and Supports Cytotoxic Lymphocyte Function., PMID:33293426

Upregulation of the expression of Toll-like receptor 9 in basophils in patients with allergic rhinitis: An enhanced expression by allergens., PMID:33247440

Future perspective: biologic agents in patients with severe COVID-19., PMID:32883116

IL-37 Exerts Anti-Inflammatory Effects in Fetal Membranes of Spontaneous Preterm Birth via the NF-κB and IL-6/STAT3 Signaling Pathway., PMID:32733162

Affimers as an alternative to antibodies for protein biomarker enrichment., PMID:32461183

IL-37 is protective in allergic contact dermatitis through mast cell inhibition., PMID:32278131

IL-37 Represses the Autoimmunity in Myasthenia Gravis via Directly Targeting Follicular Th and B Cells., PMID:32111731

Atherosclerosis: orchestrating cells and biomolecules involved in its activation and inhibition., PMID:32085889

Circulating concentration of interleukin-37 in Helicobacter pylori-infected patients with peptic ulcer: Its association with IL-37 related gene polymorphisms and bacterial virulence factor CagA., PMID:31751903

Additive Therapeutic Effects of Mesenchymal Stem Cells and IL-37 for Systemic Lupus Erythematosus., PMID:31604808

Plasma levels and expression of interleukin-37 in patients with immune thrombocytopenia., PMID:31572521

Interleukin-37 reduces inflammation and impairs phagocytosis of platelets in immune thrombocytopenia (ITP)., PMID:31557634

IL-37- and IL-35/IL-37-Producing Plasma Cells in Chronic Periodontitis., PMID:31050915

[IL-1 family cytokines in chronic inflammatory disorders]., PMID:30909697

IL-37 attenuates allergic process via STAT6/STAT3 pathways in murine allergic rhinitis., PMID:30665041

IL-37 alleviates house dust mite-induced chronic allergic asthma by targeting TSLP through the NF-κB and ERK1/2 signaling pathways., PMID:30537285

Interleukin 30 to Interleukin 40., PMID:30328794

No difference in human mast cells derived from peanut allergic versus non-allergic subjects., PMID:29992767

Impact of mast cells in depression disorder: inhibitory effect of IL-37 (new frontiers)., PMID:29907890

Increased serum interleukin-37 (IL-37) levels correlate with oxidative stress parameters in Hashimoto's thyroiditis., PMID:29796799

Transgenic Overexpression of IL-37 Protects Against Atherosclerosis and Strengthens Plaque Stability., PMID:29439249

Datasheet
$ 220
Product specifications
50 μg 220 100 μg 350

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For research use only. Not for human or drug use.

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Anti-IL37/IL1F7 Antibody (R3X03) [RHJ69502]
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