Catalog No.
RHJ69502
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
WB: 1:500-1:1000
Target
FIL1Z, IL37, Interleukin-1-related protein, IL-23, IL1F7, IL-37, IL1RP1, FIL1 zeta, IL-1X, Interleukin-23, IL-1F7, IL-1RP1, Interleukin-1 family member 7, Interleukin-37, Interleukin-1 homolog 4, Interleukin-1 zeta, IL-1H, IL-1H4, IL-1 zeta, IL1H4
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9NZH6
Applications
WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3X03
Blockade of IL-1 family cytokines in the treatment of rheumatoid arthritis., PMID:40520203
Pro-inflammatory cytokines in myasthenia gravis: a systematic review and meta-analysis., PMID:40347402
IL-37 protects against house dust mite-induced airway inflammation and airway epithelial barrier dysfunction via inhibiting store-operated calcium entry., PMID:38941668
Immune System Dysregulation in the Progression of Multiple Sclerosis: Molecular Insights and Therapeutic Implications., PMID:38692349
Targeting IL-13 with tralokinumab normalizes type 2 inflammation in atopic dermatitis both early and at 2 years., PMID:38563683
Deep resolution of clinical, cellular and transcriptomic inflammatory markers of psoriasis over 52 weeks of interleukin-17A inhibition by secukinumab., PMID:38240024
Interleukin-37 contributes to endometrial regenerative cell-mediated immunotherapeutic effect on chronic allograft vasculopathy., PMID:38159090
Correlation analysis between cytokines' profile, autoimmune antibodies and the duration of type 1 diabetes: A case control study in a specialized children's centre in Riyadh., PMID:37953627
Vasculitis Activity-Predicting Ability of IL-12 Family Cytokines in Patients with Microscopic Polyangiitis and Granulomatosis with Polyangiitis., PMID:37727919
Selected Immunohistochemical Assessment and Clinical Examinations in the Diagnosis of Palatine Tonsil Diseases., PMID:37445557
Estimation of Interleukin 32 and Interleukin 37 Serum Levels in Iraqi Patients with Rheumatoid Arthritis., PMID:37396740
Interleukin-37 inhibits desmoglein-3 endocytosis and keratinocyte dissociation via upregulation of Caveolin-1 and inhibition of the STAT3 pathway., PMID:37262304
Effect of exogenous IL-37 on immune cells from a patient carrying a potential IL37 loss-of-function variant: A case study., PMID:36476991
Mast Cell Cytokines in Acute and Chronic Gingival Tissue Inflammation: Role of IL-33 and IL-37., PMID:36362030
IL-24 Contributes to Neutrophilic Asthma in an IL-17A-Dependent Manner and Is Suppressed by IL-37., PMID:36174993
The Role of TGFβ and Other Cytokines in Regulating Mast Cell Functions in Allergic Inflammation., PMID:36142776
Anti-inflammatory, antioxidant, anti-fibrotic and schistosomicidal properties of plumbagin in murine schistosomiasis., PMID:36066812
IL-37 alleviates liver granuloma caused by Schistosoma japonicum infection by inducing alternative macrophage activation., PMID:36002836
Expression of LncRNA-BCYRN1 in pediatric asthma and related factors of disease induction., PMID:35818246
Possible association of rotavirus IgG with cytokine expression levels and dyslipidemia in rotavirus-infected type 1 diabetic children., PMID:35733062
Endogenous Levels of Gamma Amino-Butyric Acid Are Correlated to Glutamic-Acid Decarboxylase Antibody Levels in Type 1 Diabetes., PMID:35052771
Subunit-Specific Reactivity of Autoantibodies Against Laminin-332 Reveals Direct Inflammatory Mechanisms on Keratinocytes., PMID:34899732
IL-33, IL-37, and Vitamin D Interaction Mediate Immunomodulation of Inflammation in Degenerating Cartilage., PMID:34842603
Protein engineering of a stable and potent anti-inflammatory IL-37-Fc fusion with enhanced therapeutic potential., PMID:34699747
Cytokine antibody array-based analysis of IL-37 treatment effects in asthma., PMID:34516405
IL-37 Targets TSLP-Primed Basophils to Alleviate Atopic Dermatitis., PMID:34299012
Interleukin-1 Blockade in Polygenic Autoinflammatory Disorders: Where Are We now?, PMID:33708123
Elderly Subjects Supplemented with L-Glutamine Shows an Improvement of Mucosal Immunity in the Upper Airways in Response to Influenza Virus Vaccination., PMID:33572639
IL-35 and IL-37 are negatively correlated with high IgE production among children with asthma in Saudi Arabia., PMID:33492183
Targeting MARCO and IL37R on Immunosuppressive Macrophages in Lung Cancer Blocks Regulatory T Cells and Supports Cytotoxic Lymphocyte Function., PMID:33293426
Upregulation of the expression of Toll-like receptor 9 in basophils in patients with allergic rhinitis: An enhanced expression by allergens., PMID:33247440
Future perspective: biologic agents in patients with severe COVID-19., PMID:32883116
IL-37 Exerts Anti-Inflammatory Effects in Fetal Membranes of Spontaneous Preterm Birth via the NF-κB and IL-6/STAT3 Signaling Pathway., PMID:32733162
Affimers as an alternative to antibodies for protein biomarker enrichment., PMID:32461183
IL-37 is protective in allergic contact dermatitis through mast cell inhibition., PMID:32278131
IL-37 Represses the Autoimmunity in Myasthenia Gravis via Directly Targeting Follicular Th and B Cells., PMID:32111731
Atherosclerosis: orchestrating cells and biomolecules involved in its activation and inhibition., PMID:32085889
Circulating concentration of interleukin-37 in Helicobacter pylori-infected patients with peptic ulcer: Its association with IL-37 related gene polymorphisms and bacterial virulence factor CagA., PMID:31751903
Additive Therapeutic Effects of Mesenchymal Stem Cells and IL-37 for Systemic Lupus Erythematosus., PMID:31604808
Plasma levels and expression of interleukin-37 in patients with immune thrombocytopenia., PMID:31572521
Interleukin-37 reduces inflammation and impairs phagocytosis of platelets in immune thrombocytopenia (ITP)., PMID:31557634
IL-37- and IL-35/IL-37-Producing Plasma Cells in Chronic Periodontitis., PMID:31050915
[IL-1 family cytokines in chronic inflammatory disorders]., PMID:30909697
IL-37 attenuates allergic process via STAT6/STAT3 pathways in murine allergic rhinitis., PMID:30665041
IL-37 alleviates house dust mite-induced chronic allergic asthma by targeting TSLP through the NF-κB and ERK1/2 signaling pathways., PMID:30537285
Interleukin 30 to Interleukin 40., PMID:30328794
No difference in human mast cells derived from peanut allergic versus non-allergic subjects., PMID:29992767
Impact of mast cells in depression disorder: inhibitory effect of IL-37 (new frontiers)., PMID:29907890
Increased serum interleukin-37 (IL-37) levels correlate with oxidative stress parameters in Hashimoto's thyroiditis., PMID:29796799
Transgenic Overexpression of IL-37 Protects Against Atherosclerosis and Strengthens Plaque Stability., PMID:29439249
For research use only. Not for human or drug use.
