Catalog No.
RHJ68602
Species reactivity
Human
Host species
Mouse
Isotype
IgG2b
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:50-1:200
Target
TLR7, Toll-like receptor 7
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9NYK1
Applications
ELISA, FCM, IF
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3X02
Inflammatory signatures and immunomodulation in neonates: a pilot study., PMID:40525368
Common Toll-like receptor 7 variants define disease risk and phenotypes in juvenile-onset systemic lupus erythematosus., PMID:40516124
Germline-targeting HIV Envelope SOSIP immunization more frequently elicits broadly-neutralizing antibody precursor responses in infant compared to juvenile rhesus macaques., PMID:40501834
Increased Fascin1 and Pak1 Expressions Enhance Age-Associated B-Cell Actin Cytoskeleton Remodeling and Motility., PMID:40500987
Toll-like receptor engaged in activation and osteoimmuno-cytokines production by unswitched memory B cells during periodontitis., PMID:40455294
A novel cationic liposome-formulated toll like receptor (TLR) 7/8 agonist enhances the efficacy of a vaccine against fentanyl toxicity., PMID:40441493
Discovery and Characterization of a First-in-Class LIV1-TLR7/8 Immunomodulatory Conjugate with Robust Myeloid Activation and Antitumor Activity., PMID:40411528
TLR7 responses in glomerular macrophages accelerate the progression of glomerulonephritis in NZBWF1 mice., PMID:40401698
Elevated transferrin receptor 1 promoting B-cell autoimmunity in systemic lupus erythematosus., PMID:40373595
The role of age-associated B cells in systemic lupus erythematosus., PMID:40334618
Micellar formulation provides potent and tolerable TLR7 agonist treatment for anti-cancer immunotherapy., PMID:40304584
C3-Liposome Delivery of MUC1 Peptide and TLR Agonists Enhances Adaptive Immunity and Results in Sex-Based Tumor Growth Differences., PMID:40284463
Exploring TLR agonists as adjuvants for COVID-19 oral vaccines., PMID:40184639
Evaluation of dual pathogen recognition receptor agonists as adjuvants for respiratory syncytial virus - virus-like particles for pulmonary delivery., PMID:40176816
Toll-like receptor 7 (TLR7)-mediated antiviral response protects mice from lethal SARS-CoV-2 infection., PMID:40162785
Exploring the Contribution of TLR7 to Sex-Based Disparities in Respiratory Syncytial Virus (RSV)-Induced Inflammation and Immunity., PMID:40143355
Kinetically activating nanovaccine mimicking multidimensional immunomodulation of natural infection for broad protection against heterologous viruses in animal models., PMID:40133260
Rejuvenation of Tumor-Specific T Cells via Ultrahigh DAR Antibody-Polymeric Imidazoquinoline Complexes: Coordinated Targeting of PDL1 and Efficient TLR7/8 Activation in Intratumoral Dendritic Cells., PMID:40091265
IL-4 alters TLR7-induced B cell developmental program in lupus., PMID:40068727
[Immuno'logical (the scientific updates you wouldn't dare to read anywhere else): X chromosome, Xist, and female autoimmunity]., PMID:40057380
Cyclophilin-CD147 interaction enables SARS-CoV-2 infection of human monocytes and their activation via Toll-like receptors 7 and 8., PMID:39963132
Topology-Oriented Lymph Node Drainage of Dendritic Polymer-TLR Agonist Conjugates to Enhance Vaccine Immunogenicity., PMID:39962825
Targeted Delivery of TLR7 Agonists to the Tumor Microenvironment Enhances Tumor Immunity via Activation of Tumor-Resident Myeloid Cells., PMID:39948340
The systemic lupus erythematosus-associated NCF190H allele synergizes with viral infection to cause mouse lupus but also limits virus spread., PMID:39939342
Toll-like receptor upregulation in liver and peripheral blood mononuclear cells of patients with amoebic liver abscess., PMID:39919544
A cationic liposome-formulated Toll Like Receptor (TLR)7/8 agonist enhances the efficacy of a vaccine against fentanyl toxicity., PMID:39868149
Interleukin-32 positive immune and resident cells in kidney samples from lupus patients: a pilot study., PMID:39835128
Structure-Based Design of Novel TLR7/8 Agonist Payloads Enabling an Immunomodulatory Conjugate Approach., PMID:39811121
Spatiotemporal Dynamic Immunomodulation by Infection-Mimicking Gels Enhances Broad and Durable Protective Immunity Against Heterologous Viruses., PMID:39804984
Design of a Multiepitope Pan-Proteomic mRNA Vaccine Construct Against African Swine Fever Virus: A Reverse Vaccinology Approach., PMID:39803351
Immune complexes-mediated activation of neutrophils in systemic lupus erythematosus is dependent on RNA recognition by toll-like receptor 8., PMID:39776899
Induction of Tier 2 HIV-Neutralizing IgA Antibodies in Rhesus Macaques Vaccinated with BG505.664 SOSIP., PMID:39772048
Function and Regulation of Age-Associated B Cells in Diseases., PMID:39749652
The TLR7/8 agonist INI-4001 enhances the immunogenicity of a Powassan virus-like-particle vaccine., PMID:39677812
The circadian clock gene BMAL1 modulates autoimmunity features in lupus., PMID:39664388
Enhancing COVID-19 Vaccine Efficacy: Dual Adjuvant Strategies with TLR7/8 Agonists and Glycolipids., PMID:39648985
Role of STING Deficiency in Amelioration of Mouse Models of Lupus and Atherosclerosis., PMID:39605244
SHR-1806, a robust OX40 agonist to promote T cell-mediated antitumor immunity., PMID:39543823
Performance of a Global Functional Assay Based on Interferon-γ Release to Predict Infectious Complications and Cancer After Kidney Transplantation., PMID:39539802
Impact of the mare colostral immunoglobulins on the expression of TLR3, TLR4, and TLR7 in foals., PMID:39523490
Cell damage shifts the microRNA content of small extracellular vesicles into a Toll-like receptor 7-activating cargo capable to propagate inflammation and immunity., PMID:39516877
The essential roles of memory B cells in the pathogenesis of systemic lupus erythematosus., PMID:39511302
Does Epstein-Barr virus and intracellular Toll-like receptors affect the course of Hashimoto disease? Findings from studies on newly-diagnosed patients., PMID:39508448
Modulatory effects of inorganic mercury (Hg (II)) and lead (Pb (II)) on immune responses of Pekin ducklings (Anas platyrhynchos domesticus) upon a viral-like immune challenge., PMID:39500255
Co-adjuvanting Nod2-stimulating bacteria with a TLR7 agonist elicits potent protective immunity against respiratory virus infection., PMID:39477030
A Fentanyl Hapten-Displaying Lipid Nanoparticle Vaccine that Non-Covalently Encapsulates a TLR7/8 Agonist and T-Helper Epitope Induces Protective Anti-Fentanyl Immunity., PMID:39441822
Modulation of the Adjuvant Potential of Imidazoquinoline-Based TLR7/8 Agonists via Alum Adsorption., PMID:39411538
Purified Astragalus Polysaccharide Combined with Inactivated Vaccine Markedly Prevents Infectious Haematopoietic Necrosis Virus Infection in Rainbow Trout (Oncorhynchus mykiss)., PMID:39375226
DSP-0509, a TLR7 agonist, exerted synergistic anti-tumor immunity combined with various immune therapies through modulating diverse immune cells in cancer microenvironment., PMID:39346737
B cell targeting in IgA nephropathy., PMID:39327767
For research use only. Not for human or drug use.
