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Anti-MUC5B Antibody (R3W65)

Catalog #:   RHJ60303 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: ELISA, FCM
Accession: Q9HC84
Overview

Catalog No.

RHJ60303

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400

Target

MUC5, High molecular weight salivary mucin MG1, Mucin-5 subtype B, tracheobronchial, Mucin-5B, MUC5B, MUC-5B, Sublingual gland mucin, Cervical mucin

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9HC84

Applications

ELISA, FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3W65

Data Image
  • Flow Cytometry
    Flow cytometric analysis of Hela cells using MUC5B mouse mAb (green) and negative control (red).
References

The Role of Pulmonary Genetic Variations in the Pathogenesis of Pediatric Postinfectious Bronchiolitis Obliterans., PMID:40196942

Detection of MUC1+/MUC2 and MUC5AC- Membrane-Associated Mucins in the Intraepithelial Surface Mucous Cells of the Developing Rabbit Esophagus., PMID:39396509

RSV infection of humanized lung-only mice induces pathological changes resembling severe bronchiolitis and bronchopneumonia., PMID:39175804

A novel immunofluorescence study of Lingual Salivary Glands in the Egyptian Tortoise (Testudo kleinmanni) and its ecological significance., PMID:39137537

High-throughput proteomic analysis of extracellular vesicles from saliva by chemical probe-based array., PMID:38772652

Down-Regulation of INSR Restores Th17/Treg Immune Balance and Alleviates Airway Hyperviscosity in Asthmatic Mice via Inactivation of STAT3 Pathway., PMID:38409842

Characterization of MdpS: an in-depth analysis of a MUC5B-degrading protease from Streptococcus oralis., PMID:38304711

Patient-level factors predictive of interstitial lung disease in rheumatoid arthritis: a systematic review., PMID:37507209

Genetic regulators of sputum mucin concentration and their associations with COPD phenotypes., PMID:37352370

Characterization of a highly conserved MUC5B-degrading protease, MdpL, from Limosilactobacillus fermentum., PMID:36925480

Exogenous Lipoxin A4 attenuates IL4-induced Mucin Expression in Human Airway Epithelial Cells., PMID:36860679

Identification and Characterization of MUC5B Binding Peptides by Phage Display., PMID:36701953

Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules., PMID:35776514

Novel Biomarkers, Diagnostic and Therapeutic Approach in Rheumatoid Arthritis Interstitial Lung Disease-A Narrative Review., PMID:35740390

Basiliximab Does Not Impair Airway Mucociliary Clearance of Rats., PMID:35715590

Anti-citrullinated protein antibody specificities and pulmonary fibrosis in relation to genetic loci in early rheumatoid arthritis., PMID:35532073

Study Effect of Azithromycin and Doxycycline in Mucus Producing and Inflammatory Signaling Pathways of Allergic Asthma., PMID:35490266

Bronchodilatory effect of higenamine as antiallergic asthma treatment., PMID:35410888

PlexinD1 Deficiency in Lung Interstitial Macrophages Exacerbates House Dust Mite-Induced Allergic Asthma., PMID:35110420

Mucins 5b and 7 and secretory IgA in the oral acquired pellicle of children with caries and caries-free children., PMID:34861462

Assessing predictors of rheumatoid arthritis-associated interstitial lung disease using quantitative lung densitometry., PMID:34747452

Lung macrophages drive mucus production and steroid-resistant inflammation in chronic bronchitis., PMID:34098956

Pregnancy-associated decrease of Siaα2-3Gal-linked glycans on salivary glycoproteins affects their binding ability to avian influenza virus., PMID:34097968

Pulmonary fibrosis in relation to genetic loci in an inception cohort of patients with early rheumatoid arthritis from northern Sweden., PMID:33993221

Association of TERT and DSP variants with microscopic polyangiitis and myeloperoxidase-ANCA positive vasculitis in a Japanese population: a genetic association study., PMID:33076992

Rheumatoid arthritis-associated interstitial lung disease: an overview of epidemiology, pathogenesis and management., PMID:32794076

The Association Between MUC5B Mutations and Clinical Outcome in Patients with Rheumatoid Arthritis-Associated Interstitial Lung Disease: A Retrospective Exploratory Study in China., PMID:32142504

Influence of MUC5B gene on antisynthetase syndrome., PMID:31996780

Involvement of PM2.5-bound protein and metals in PM2.5-induced allergic airway inflammation in mice., PMID:30849251

Association of MUC5B promoter polymorphism with interstitial lung disease in myeloperoxidase-antineutrophil cytoplasmic antibody-associated vasculitis., PMID:30765393

NOTCH3 contributes to rhinovirus-induced goblet cell hyperplasia in COPD airway epithelial cells., PMID:29991510

Characterization of mucoid and serous middle ear effusions from patients with chronic otitis media: implication of different biological mechanisms?, PMID:29915406

Early salivary changes in multiple myeloma patients undergoing autologous HSCT., PMID:29637662

A detection and quantification label-free tool to speed up downstream processing of model mucins., PMID:29315346

SLC3A2, antigen of mAb 3G9, promotes migration and invasion by upregulating of mucins in gastric cancer., PMID:29179459

Biofunctionalized Hybrid Magnetic Gold Nanoparticles as Catalysts for Photothermal Ablation of Colorectal Liver Metastases., PMID:28707960

Early Postnatal Secondhand Smoke Exposure Disrupts Bacterial Clearance and Abolishes Immune Responses in Muco-Obstructive Lung Disease., PMID:28667160

[Mucous cell differentiation and regulation of the gelling mucin Muc5b: a new tool for ex vivo and in vivo preclinical studies]., PMID:28612718

Innate immune defense in the inner ear - mucines are expressed by the human endolymphatic sac., PMID:28106268

Presence of DNA extracellular traps but not MUC5AC and MUC5B mucin in mucoid plugs/casts of infectious laryngotracheitis virus (ILTV) infected tracheas of chickens., PMID:27756631

Astragalus polysaccharide modulates ER stress response in an OVA-LPS induced murine model of severe asthma., PMID:27645929

MUC Expression in Gallbladder Epithelial Tissues in Cholesterol-Associated Gallbladder Disease., PMID:27563024

Detection and quantification of epithelial progenitor cell populations in human healthy and IPF lungs., PMID:27423691

Biosynthesis of the polymeric gel-forming mucin MUC5B., PMID:26993521

Meibomian Gland Absence Related Dry Eye in Ectodysplasin A Mutant Mice., PMID:26626448

Secretory IgA from submucosal glands does not compensate for its airway surface deficiency in chronic obstructive pulmonary disease., PMID:26432569

Interindividual variation, correlations, and sex-related differences in the salivary biochemistry of young healthy adults., PMID:25809904

Salivary mucins induce a Toll-like receptor 4-mediated pro-inflammatory response in human submandibular salivary cells: are mucins involved in Sjögren's syndrome?, PMID:25802401

SIgA binding to mucosal surfaces is mediated by mucin-mucin interactions., PMID:25793390

DNA methylation and childhood asthma in the inner city., PMID:25769910

Datasheet

Document Download

Anti-MUC5B Antibody (R3W65).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-MUC5B Antibody (R3W65) [RHJ60303]
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