Catalog No.
RHJ56804
Species reactivity
Human, Mouse, Rat
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
IHC: 1:50-1:100, WB: 1:500-1:1000
Target
Autophagy-related protein LC3 A, Autophagy-related ubiquitin-like modifier LC3 A, MAP1 light chain 3-like protein 1, Microtubule-associated protein 1 light chain 3 alpha, MAP1A/MAP1B LC3 A, MAP1LC3A, Microtubule-associated proteins 1A/1B light chain 3A, MAP1A/MAP1B light chain 3 A
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9H492
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.5% BSA, 0.05% Sodium Azide and 50% Glycerol.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3W50
Renal Expression Levels of C5a Receptor and Autophagy-related Beclin-1 and LC3A/B Are Simultaneously Enhanced Under Immunoglobulin Treatment in a Rat Model of Sepsis., PMID:40010959
Autophagy Blockage Up-Regulates HLA-Class-I Molecule Expression in Lung Cancer and Enhances Anti-PD-L1 Immunotherapy Efficacy., PMID:39409895
Does Autophagy have a Role in the Pathogenesis of Pediatric Hepatic Steatosis?, PMID:38809648
Acute muscle mass loss was alleviated with HMGB1 neutralizing antibody treatment in severe burned rats., PMID:37355693
Mechanisms in Graves Eye Disease: Apoptosis as the End Point of Insulin-Like Growth Factor 1 Receptor Inhibition., PMID:34927457
Effects of in vitro vitamin D treatment on function of T cells and autophagy mechanisms in high-fat diet-induced obese mice., PMID:34858547
Autophagy-related Prognostic Signature in HER2 Positive Gastric Carcinomas., PMID:34814818
Rescue of thyroid cells from antibody induced cell death via induction of autophagy., PMID:34801870
Mucin 1 as a Molecular Target of a Novel Diisoquinoline Derivative Combined with Anti-MUC1 Antibody in AGS Gastric Cancer Cells., PMID:34770912
Interaction of Poliovirus Capsid Proteins with the Cellular Autophagy Pathway., PMID:34452452
Anti-HER2 monoclonal antibodies intensify the susceptibility of human gastric cancer cells to etoposide by promoting apoptosis, but not autophagy., PMID:34437575
IF1 inactivation attenuates experimental colitis through downregulation of neutrophil infiltration in colon mucosa., PMID:34298397
Kaiso (ZBTB33) subcellular partitioning functionally links LC3A/B, the tumor microenvironment, and breast cancer survival., PMID:33526872
Pancreatic beta cell autophagy is impaired in type 1 diabetes., PMID:33515072
Novel Insights into the Cellular Localization and Regulation of the Autophagosomal Proteins LC3A, LC3B and LC3C., PMID:33081014
Autophagy core protein ATG5 is required for elongating spermatid development, sperm individualization and normal fertility in male mice., PMID:32677505
Tumor autophagy is associated with survival outcomes in patients with resected non-small cell lung cancer., PMID:30797498
Characterization of the "Autophagic Flux" in Prostate Cancer Tissue Biopsies by LC3A/LAMP2a Immunofluorescence and Confocal Microscopy., PMID:30610722
LC3A, LC3B and Beclin-1 Expression in Gastric Cancer., PMID:30504397
Identification of New Potential Therapies for Colitis Amelioration Using an Appendicitis-Appendectomy Model., PMID:30329049
Activation of the SphK1/ERK/p-ERK pathway promotes autophagy in colon cancer cells., PMID:29928348
Lysosomes, autophagosomes and Alzheimer pathology in dementia with Lewy body disease., PMID:29748975
TRAIL DR5-CTSB crosstalk participates in breast cancer autophagy initiated by SAHA., PMID:29018571
Autophagosome Proteins LC3A, LC3B and LC3C Have Distinct Subcellular Distribution Kinetics and Expression in Cancer Cell Lines., PMID:26378792
Prospective neoadjuvant analysis of PET imaging and mechanisms of resistance to Trastuzumab shows role of HIF1 and autophagy., PMID:24722179
Autophagy proteins in prostate cancer: relation with anaerobic metabolism and Gleason score., PMID:23787295
Overexpression of LC3A autophagy protein in follicular and diffuse large B-cell lymphomas., PMID:23664601
Inhibition of the host translation shutoff response by herpes simplex virus 1 triggers nuclear envelope-derived autophagy., PMID:23365427
Patterns of autophagy in urothelial cell carcinomas--the significance of "stone-like" structures (SLS) in transurethral resection biopsies., PMID:22281431
"Autophagic flux" in normal mouse tissues: focus on endogenous LC3A processing., PMID:21997374
LC3A-positive "stone-like" structures in cutaneous squamous cell carcinomas., PMID:21430508
Light-chain 3A autophagic activity and prognostic significance in non-small cell lung carcinomas., PMID:21148243
Autophagy in endometrial carcinomas and prognostic relevance of 'stone-like' structures (SLS): what is destined for the atypical endometrial hyperplasia?, PMID:21099253
Altered autophagy in human adipose tissues in obesity., PMID:21047928
The "stone-like" pattern of autophagy in human epithelial tumors and tumor-like lesions: an approach to the clinical outcome., PMID:20622525
LC3A-positive light microscopy detected patterns of autophagy and prognosis in operable breast carcinomas., PMID:20382705
For research use only. Not for human or drug use.
