Catalog No.
RHJ55601
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IHC: 1:200-1:1000
Target
C-X-C motif chemokine 16, CXCL16, Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein, Small-inducible cytokine B16, Transmembrane chemokine CXCL16, SRPSOX, SR-PSOX, SCYB16
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9H2A7
Applications
ELISA, FCM, IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3W42
Administration of lipid nanoparticle-encapsulated mRNA encoding CCR7, CXCL16 and GITRL effectively mobilizes antitumor T cell immunity., PMID:40451345
Hydroxychloroquine cures autoimmune myocarditis by inhibiting the innate immune system via the C-X-C motif chemokine ligand 16 and C-X-C motif receptor 6 axis between macrophages and T cells., PMID:40222951
Deciphering the IgG Idiotype Network Through Proteomic Analysis of Potential Targets in SARS-CoV-2-Induced Immune Responses., PMID:40077865
Exploring the Regulatory Mechanism of CXCL16 Molecule-Related Antigen Presentation Using lncRNA-mRNA Co-Expression Network Analysis., PMID:39735899
Safety of baricitinib in vaccinated patients with severe and critical COVID-19 sub study of the randomised Bari-SolidAct trial., PMID:39731852
IgG autoantibodies in bullous pemphigoid directly induce a pathogenic MyD88-dependent pro-inflammatory response in keratinocytes., PMID:39569141
Toxoplasma gondii infection induces the expression of the chemokine CXCL16 in macrophages to promote chemoattraction of CXCR6+ cells., PMID:39436058
Immunoliposome-based targeted delivery of the CRISPR/Cas9gRNA-IL30 complex inhibits prostate cancer and prolongs survival., PMID:39232121
ITGB6 modulates resistance to anti-CD276 therapy in head and neck cancer by promoting PF4+ macrophage infiltration., PMID:39152118
Soluble CXCL16 is a prognostic biomarker associated with rapidly progressive interstitial lung disease complicated with dermatomyositis., PMID:38843569
Role of Novel Inflammatory Factors in Central Retinal Vein Occlusion with Macular Edema., PMID:38276038
CXCL16 exacerbates Pseudomonas aeruginosa keratitis by promoting neutrophil activation., PMID:38154213
Mucosal-associated invariant T cells contribute to suppression of inflammatory myeloid cells in immune-mediated kidney disease., PMID:37968302
S1PR1-dependent migration of ILC3s from intestinal tissue to the heart in a mouse model of viral myocarditis., PMID:37141387
Upregulation of IL-33, CCL2, and CXCL16 levels in Brazilian pregnant women infected by Toxoplasma gondii., PMID:37086937
Integrative characterisation of secreted factors involved in intercellular communication between prostate epithelial or cancer cells and fibroblasts., PMID:36608258
Reduced expression of CXCL16/CXCR6 is involved in the pathogenesis of hidradenitis suppurativa., PMID:36394347
CXCL16 inhibits epithelial regeneration and promotes fibrosis during the progression of radiation enteritis., PMID:36373877
Single-cell RNA transcriptome analysis of CNS immune cells reveals CXCL16/CXCR6 as maintenance factors for tissue-resident T cells that drive synapse elimination., PMID:36153630
Assessing the Immune Cell Subset and Genetic Mutations in Patients With Palindromic Rheumatism Seronegative for Rheumatoid Factor and Anti-Cyclic Citrullinated Peptide., PMID:35819819
Clinical significance and role of CXCL16 in anti-neutrophil cytoplasmic autoantibody-associated vasculitis., PMID:35120907
Transcriptional regulation of chemokine network by biologic monotherapy in ileum of patients with Crohn's disease., PMID:35078095
TNF-α Activating Osteoclasts in Patients with Psoriatic Arthritis Enhances the Recruitment of Osteoclast Precursors: A Plausible Role of WNT5A-MCP-1 in Osteoclast Engagement in Psoriatic Arthritis., PMID:35055107
Nano delivery of simvastatin targets liver sinusoidal endothelial cells to remodel tumor microenvironment for hepatocellular carcinoma., PMID:34983554
Beneficial effects of PCSK9 inhibition with alirocumab in familial hypercholesterolemia involve modulation of new immune players., PMID:34864314
Prognostic and pathogenic role of CXC motif ligand 16 in sepsis., PMID:34454064
Dendritic cells maintain anti-tumor immunity by positioning CD8 skin-resident memory T cells., PMID:34362825
CXCR6-CXCL16 Axis Promotes Breast Cancer by Inducing Oncogenic Signaling., PMID:34298782
Advances in Chemokine Signaling Pathways as Therapeutic Targets in Glioblastoma., PMID:34203660
Small molecule Y-320 stimulates ribosome biogenesis, protein synthesis, and aminoglycoside-induced premature termination codon readthrough., PMID:33939688
High miR-451 expression in peripheral blood mononuclear cells from subjects at risk of developing rheumatoid arthritis., PMID:33633196
Assessment of Adipokines, CXCL16 Chemokine Levels in Patients With Rheumatoid Arthritis Combined With Metabolic Syndrome., PMID:33613035
T cell-depleted cultured pediatric thymus tissue as a model for some aspects of human age-related thymus involution., PMID:33420705
Identification of in vitro and in vivo oncolytic effect in colorectal cancer cells by Orf virus strain NA1/11., PMID:33416161
Crucial transcripts predict response to initial immunoglobulin treatment in acute Kawasaki disease., PMID:33082496
Targeting Chemokines and Chemokine Receptors in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis., PMID:33061527
Heightened Levels of Antimicrobial Response Factors in Patients With Rheumatoid Arthritis., PMID:32265916
New strategies for Leptospira vaccine development based on LPS removal., PMID:32218590
The expression of cytokines in aqueous humor of high myopic patients with cataracts., PMID:32180680
The clinical significance of CXCL16 in the treatment of advanced non-small cell lung cancer., PMID:32163231
TNF Receptor: Fc Fusion Protein Downregulates RANKL/OPG Ratio by Inhibiting CXCL16/CXCR6 in Active Ankylosing Spondylitis., PMID:32116188
Atherosclerosis: orchestrating cells and biomolecules involved in its activation and inhibition., PMID:32085889
Spread of equine arteritis virus among Hucul horses with different EqCXCL16 genotypes and analysis of viral quasispecies from semen of selected stallions., PMID:32076048
Mesenchymal stem cell-derived CXCL16 promotes progression of gastric cancer cells by STAT3-mediated expression of Ror1., PMID:32012403
Monocytes treated with ciprofloxacin and oxyLDL express myristate, priming atherosclerosis., PMID:31926051
CXCL16/CXCR6 axis promotes bleomycin-induced fibrotic process in MRC-5 cells via the PI3K/AKT/FOXO3a pathway., PMID:31753588
Extensive serum biomarker analysis in patients with non-small-cell lung carcinoma., PMID:31629110
CXCL16 Induces the Progression of Pulmonary Fibrosis through Promoting the Phosphorylation of STAT3., PMID:31379980
Equine arteritis virus long-term persistence is orchestrated by CD8+ T lymphocyte transcription factors, inhibitory receptors, and the CXCL16/CXCR6 axis., PMID:31356622
Coordinated Induction of Antimicrobial Response Factors in Systemic Lupus Erythematosus., PMID:31019506