Catalog No.
YHD67401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Ile340
Predicted molecular weight
40.35 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P25685
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
DnaJ protein homolog 1, HSP40, DnaJ homolog subfamily B member 1, DNAJB1, DNAJ1, Heat shock 40 kDa protein 1, hDj-1, HDJ1, Human DnaJ protein 1, Heat shock protein 40, HSPF1
Plantamajoside: A potentially novel botanical agent for diabetes mellitus management., PMID:40487597
Chaperone-mediated heterotypic phase separation regulates liquid-to-solid phase transitions of tau into amyloid fibrils., PMID:40479073
Uncovering the Role of the Hsp40 Family Member, Cysteine String Protein-α, in Mouse Platelets., PMID:40472286
A low-complexity linker as a driver of intra- and intermolecular interactions in DNAJB chaperones., PMID:40450039
Comparative Transcriptome Analysis Elucidates the Desiccation Stress Adaptation in Sargassum muticum., PMID:40428409
Dynamics of heat shock protein 70 kDa in heat-shocked and hypoxic human endothelial cells., PMID:40425101
Impaired DNAJB2 Response to Heat Shock in Fibroblasts from a Neuropathy Patient with DNAJB2/HSJ1 Mutation: Cystamine as a Potential Therapeutic Intervention., PMID:40423229
Evaluation of aggrephagy markers in myofibrillar myopathies., PMID:40413523
Novel interaction with PSMD9 regulates DNAJA1 turnover and mitochondrial polarity., PMID:40412052
DNAJC9 Binds to and Enhances the Transcription of Hepatitis B Virus cccDNA by Recruiting Histone H3.3., PMID:40407066
Neuronal lipofuscinosis caused by Kufs disease/CLN4 DNAJC5 mutations but not by a CSPα/DNAJC5 deficiency., PMID:40397740
Chaperone overexpression boosts heterologous small molecule production in Saccharomyces cerevisiae., PMID:40383781
Cardiomyocyte-specific activation of the sarcomere-localized Dnajb6b chaperone causes cardiomyopathy and heart failure through upregulated sarcoplasmic reticulum stress., PMID:40360088
Comprehensive analysis of growth performance, antioxidant capacity, digestive enzyme activity, and transcriptomics provides insights into the chronic high-temperature stress response of brass gudgeon (Coreius heterodon) in the Yangtze River., PMID:40327220
Exploring therapeutic strategies based on chaperon-mediated disaggregation., PMID:40324847
OsNAL11 and OsBURP12 Affect Rice Seed Germination at Low Temperature., PMID:40320839
Increased expression of DNAJC7 promotes the progression of hepatocellular carcinoma by influencing the cell cycle and immune microenvironment., PMID:40312488
The Role of α-Synuclein-DNAJB6b Coaggregation in Amyloid Suppression., PMID:40304428
Role of HSP40 proteins in genome maintenance, insulin signaling and cancer therapy., PMID:40267605
Structural-functional relevance of DNAJBs in protein aggregation and associated neurodegenerative diseases., PMID:40254275
NIR-II Photosensitizer-Based Nanoparticles Defunctionalizing Mitochondria to Overcome Tumor Self-Defense by Promoting Heat Shock Protein 40., PMID:40241294
DNAJA3 interacts with ASFV MGF360-14L protein and reduces MGF360-14L antagonistic role on Beta interferon production., PMID:40233912
Hsp70 chaperones, Ssa1 and Ssa2, limit poly(A) binding protein aggregation., PMID:40202836
Cytosolic and endoplasmic reticulum chaperones inhibit wt-p53 to increase cancer cells' survival by refluxing ER-proteins to the cytosol., PMID:40202782
The impact of a heat therapy intervention on pain and fibromyalgia symptoms in patients with fibromyalgia: a pilot study., PMID:40182803
Effects of chronic high-temperature stress on muscle tissue integrity and metabolism-related genes in Clarias fuscus., PMID:40174404
Stepwise recruitment of chaperone Hsc70 by DNAJB1 produces ordered arrays primed for bursts of amyloid fibril disassembly., PMID:40159506
Regulation of gene expression under temperature stress and genome-wide analysis of heat shock protein family in Eriocheir sinensis., PMID:40139619
Structural recognition and stabilization of tyrosine hydroxylase by the J-domain protein DNAJC12., PMID:40113792
The DnaJ1 heat shock protein interacts with the flavanone 3-hydroxylase-like protein F3HL to synergistically enhance drought tolerance by scavenging reactive oxygen species in tomato., PMID:40089906
The deubiquitinase inhibitor WP1130 drives nuclear aggregation and reactivation of mutant p53 for selective cancer cell targeting., PMID:40070163
Physiological responses and adaptive mechanisms of the harmful algal bloom species Heterosigma akashiwo to naphthalene exposure., PMID:40056521
Two sides of the same coin: heat shock proteins as biomarkers and therapeutic targets for some complex diseases., PMID:40051500
Downregulation of DNAJC12 Expression Predicts Worse Survival for ER-Positive Breast Cancer Patients., PMID:40008192
Role of heat shock proteins in response to temperature stress and their effect on apoptosis in Drosophila melanogaster., PMID:39984102
Expression analysis of molecular chaperones associated with disaggregation complex in rotenone-induced Parkinsonian rat model., PMID:39952347
A novel high-throughput screening platform to identify inhibitors of DNAJB1-PRKACA-driven transcriptional activity in fibrolamellar carcinoma., PMID:39947627
On the thermal and chemical stability of DNAJB6b and its globular domains., PMID:39938325
Impaired cognitive function and decreased monoamine neurotransmitters in the DNAJC12 gene knockout mouse model., PMID:39923104
De novo designed Hsp70 activator dissolves intracellular condensates., PMID:39922190
Dnajc5b contributes to male fertility by maintaining the mitochondrial functions and autophagic homeostasis during spermiogenesis., PMID:39899042
The mitochondrial DNAJC co-chaperone TCAIM reduces α-ketoglutarate dehydrogenase protein levels to regulate metabolism., PMID:39889707
A pentatomomorpha-specific salivary protein activates plant immunity and is critical for insect feeding., PMID:39888915
Hsp90, DnaK, and ClpB collaborate in protein reactivation., PMID:39879241
The ortholog of human DNAJC9 promotes histone H3-H4 degradation and is counteracted by Asf1 in fission yeast., PMID:39878217
Molecular hallmarks of excitatory and inhibitory neuronal resilience and resistance to Alzheimer's disease., PMID:39868232
Chaperone-Mediated Heterotypic Phase Separation Prevents the Amyloid Formation of the Pathological Y145Stop Prion Protein Variant., PMID:39826709
How Do I Diagnose Fibrolamellar Carcinoma?, PMID:39814265
Mitochondrial chaperonin DNAJC15 promotes vulnerability to ferroptosis of chemoresistant ovarian cancer cells., PMID:39809321
NMR Studies on the Structure of Yeast Sis1 and the Dynamics of Its Interaction with Ssa1-EEVD., PMID:39795068
For research use only. Not for human or drug use.
