Catalog No.
RHJ53701
Species reactivity
Human
Host species
Mouse
Isotype
IgG2b
Clonality
Monoclonal
Tested applications
IHC: 1:20-1:100, IP: 1:100-1:200, WB: 1:500-1:1000
Target
NTAL, LAT2, Membrane-associated adapter molecule, WBS15, LAB, WBSCR15, Williams-Beuren syndrome chromosomal region 5 protein, WBSCR5, Non-T-cell activation linker, Linker for activation of T-cells family member 2, Linker for activation of B-cells, Williams-Beuren syndrome chromosomal region 15 protein
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9GZY6
Applications
IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3W34
Targeting LAT1 with JPH203 to reduce TNBC proliferation and reshape suppressive immune microenvironment by blocking essential amino acid uptake., PMID:40379991
Peritoneal autoantibody profiling identifies p53 as an autoantibody target in endometriosis., PMID:36828054
Structure of the human heterodimeric transporter 4F2hc-LAT2 in complex with Anticalin, an alternative binding protein for applications in single-particle cryo-EM., PMID:36310334
A Novel Blood-Brain Barrier-Permeable Chemotherapeutic Agent for the Treatment of Glioblastoma., PMID:34646647
Choroid plexus LAT2 and SNAT3 as partners in CSF amino acid homeostasis maintenance., PMID:32046769
Cytoskeletal Protein 4.1R Is a Positive Regulator of the FcεRI Signaling and Chemotaxis in Mast Cells., PMID:31993060
Signature of genome wide gene expression in classical swine fever virus infected macrophages and PBMCs of indigenous vis-a-vis crossbred pigs., PMID:31935504
LAT is essential for the mast cell stabilising effect of tHGA in IgE-mediated mast cell activation., PMID:28813645
Don't trust an(t)ybody - Pitfalls during investigation of candidate proteins for methylmercury transport at the placental interface., PMID:27324094
Induction of inducible nitric oxide synthase expression in ammonia-exposed cultured astrocytes is coupled to increased arginine transport by upregulated y(+)LAT2 transporter., PMID:26448619
Integration of computational modeling with membrane transport studies reveals new insights into amino acid exchange transport mechanisms., PMID:25761365
Runx1t1 (Runt-related transcription factor 1; translocated to, 1) epigenetically regulates the proliferation and nitric oxide production of microglia., PMID:24586690
Molecular editing of cellular responses by the high-affinity receptor for IgE., PMID:24505132
Cellular localization of glutamate and glutamine metabolism and transport pathways in the rat ciliary epithelium., PMID:21593199
Properties of L-type amino acid transporter 1 in epidermal ovarian cancer., PMID:20375792
Investigation of the mechanism by which herpes simplex virus type 1 LAT sequences modulate preferential establishment of latent infection in mouse trigeminal ganglia., PMID:19493993
Regulation of amino acid transporters in the rat remnant kidney., PMID:19155532
Analysis of the linker for activation of T cells and the linker for activation of B cells in natural killer cells reveals a novel signaling cassette, dual usage in ITAM signaling, and influence on development of the Ly49 repertoire., PMID:18645037
Identification of a new transmembrane adaptor protein that constitutively binds Grb2 in B cells., PMID:18559951
Production and characterization of highly tumor-specific rat monoclonal antibodies recognizing the extracellular domain of human L-type amino-acid transporter 1., PMID:18294274
Basolateral aromatic amino acid transporter TAT1 (Slc16a10) functions as an efflux pathway., PMID:16245314
Expression of LAT1 and LAT2 amino acid transporters in human and rat intestinal epithelial cells., PMID:16027961
L-type amino acid transporter 1-mediated L-leucine transport at the inner blood-retinal barrier., PMID:15980244
[B cell receptor signal transduction]., PMID:15861676
CD98 and intracellular adhesion molecule I regulate the activity of amino acid transporter LAT-2 in polarized intestinal epithelia., PMID:12716892
Non-T cell activation linker (NTAL): a transmembrane adaptor protein involved in immunoreceptor signaling., PMID:12486104
Characterization of the system L amino acid transporter in T24 human bladder carcinoma cells., PMID:12225859
Limnanthes douglasii lysophosphatidic acid acyltransferases: immunological quantification, acyl selectivity and functional replacement of the Escherichia coli plsC gene., PMID:12049644
Cross-talk between RANKL and FRP-1/CD98 Systems: RANKL-mediated osteoclastogenesis is suppressed by an inhibitory anti-CD98 heavy chain mAb and CD98-mediated osteoclastogenesis is suppressed by osteoclastogenesis inhibitory factor., PMID:11243701
The 4F2hc/LAT1 complex transports L-DOPA across the blood-brain barrier., PMID:11011012
For research use only. Not for human or drug use.
