Catalog No.
RHJ44003
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IHC: 1:200-1:1000, WB: 1:500-1:2000
Target
Parkinson disease protein 7, Oncogene DJ1, Parkinsonism-associated deglycase, DJ-1, PARK7, Maillard deglycase, Protein/nucleic acid deglycase DJ-1, Protein DJ-1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q99497
Applications
ELISA, FCM, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3V94
Parkinson biomarker determination with an Au microflower-enhanced electrochemical immunosensor using non-Faradaic capacitance measurements., PMID:39392501
A reduced proteomic signature in critically ill Covid-19 patients determined with plasma antibody micro-array and machine learning., PMID:38760690
Extracellular DJ-1 induces sterile inflammation in the ischemic brain., PMID:34014921
Effect of kaempferol on IgE-mediated anaphylaxis in C57BL/6 mice and LAD2 cells., PMID:33002828
Flexible platinum electrodes as electrochemical sensor and immunosensor for Parkinson's disease biomarkers., PMID:32056736
Evaluation of a panel of tumor-associated antigens in breast cancer., PMID:31839604
Serum biomarkers in patients suspected of transient ischaemic attack in primary care: a diagnostic accuracy study., PMID:31628130
Improved detection of prostate cancer using a magneto-nanosensor assay for serum circulating autoantibodies., PMID:31404106
Emerging views of mitophagy in immunity and autoimmune diseases., PMID:30951392
The deglycase activity of DJ-1 mitigates α-synuclein glycation and aggregation in dopaminergic cells: Role of oxidative stress mediated downregulation of DJ-1 in Parkinson's disease., PMID:30796974
Distribution of oxidized DJ-1 in Parkinson's disease-related sites in the brain and in the peripheral tissues: effects of aging and a neurotoxin., PMID:30104666
DJ-1 as a Biomarker of Parkinson's Disease., PMID:29147908
Interaction of DJ-1 with Lyn is essential for IgE-mediated stimulation of human mast cells., PMID:29031599
NRG-1 Stimulates Serum DJ-1 Increase in Breast Cancers., PMID:28963699
Primary bovine skeletal muscle cells enters apoptosis rapidly via the intrinsic pathway when available oxygen is removed., PMID:28792534
Exosomal proteins as prostate cancer biomarkers in urine: From mass spectrometry discovery to immunoassay-based validation., PMID:27664330
Regulation of Reactive Oxygen Species and the Antioxidant Protein DJ-1 in Mastocytosis., PMID:27611333
Novel association of DJ-1 with HER3 potentiates HER3 activation and signaling in cancer., PMID:27582551
Oxidation and interaction of DJ-1 with 20S proteasome in the erythrocytes of early stage Parkinson's disease patients., PMID:27470541
The Parkinsonism-associated protein DJ-1/Park7 prevents glycation damage in human keratinocyte., PMID:26995087
Microglia-Derived Cytokines/Chemokines Are Involved in the Enhancement of LPS-Induced Loss of Nigrostriatal Dopaminergic Neurons in DJ-1 Knockout Mice., PMID:26982707
Oxidant-induced Interprotein Disulfide Formation in Cardiac Protein DJ-1 Occurs via an Interaction with Peroxiredoxin 2., PMID:26945066
DJ-1-dependent protective activity of DJ-1-binding compound no. 23 against neuronal cell death in MPTP-treated mouse model of Parkinson's disease., PMID:25837927
Local immunosuppressive microenvironment enhances migration of melanoma cells to lungs in DJ-1 knockout mice., PMID:25706411
Immunostaining of oxidized DJ-1 in human and mouse brains., PMID:24918637
Oxidized DJ-1 as a possible biomarker of Parkinson's disease., PMID:24894116
Oxygen-glucose-deprived rat primary neural cells exhibit DJ-1 translocation into healthy mitochondria: a potent stroke therapeutic target., PMID:24382215
Insights into the prognostic value of DJ-1 and MIB-1 in astrocytic tumors., PMID:23902708
DJ-1 cooperates with PYCR1 in cell protection against oxidative stress., PMID:23743200
The positive correlation between DJ-1 and β-catenin expression shows prognostic value for patients with glioma., PMID:23714193
Immunohistochemical study of the Nrf2 pathway in colorectal cancer: Nrf2 expression is closely correlated to Keap1 in the tumor and Bach1 in the normal tissue., PMID:23455180
Protective effect of planarian DJ-1 against 6-hydroxydopamine-induced neurotoxicity., PMID:23026478
Decline in DJ-1 and decreased nuclear translocation of Nrf2 in Fuchs endothelial corneal dystrophy., PMID:22836768
Age-related changes in the retinal pigment epithelium (RPE)., PMID:22701690
Parkinson's disease-associated DJ-1 mutations impair mitochondrial dynamics and cause mitochondrial dysfunction., PMID:22428580
YajL, prokaryotic homolog of parkinsonism-associated protein DJ-1, functions as a covalent chaperone for thiol proteome., PMID:22157000
Autoantibody signatures as biomarkers to distinguish prostate cancer from benign prostatic hyperplasia in patients with increased serum prostate specific antigen., PMID:22146597
Nuclear factor erythroid-derived 2-like 2 (Nrf2) and DJ1 are prognostic factors in lung cancer., PMID:21943684
Elevation of oxidized DJ-1 in the brain and erythrocytes of Parkinson disease model animals., PMID:20708070
DJ-1 and alpha-synuclein in human cerebrospinal fluid as biomarkers of Parkinson's disease., PMID:20157014
The cytotoxic pathway triggered by palytoxin involves a change in the cellular pool of stress response proteins., PMID:19928802
Oxidation of DJ-1-dependent cell transformation through direct binding of DJ-1 to PTEN., PMID:19885556
Preparation and application of monoclonal antibodies against oxidized DJ-1. Significant elevation of oxidized DJ-1 in erythrocytes of early-stage Parkinson disease patients., PMID:19733211
Oxidative status of DJ-1-dependent activation of dopamine synthesis through interaction of tyrosine hydroxylase and 4-dihydroxy-L-phenylalanine (L-DOPA) decarboxylase with DJ-1., PMID:19703902
Proteomic analysis identifies MMP-9, DJ-1 and A1BG as overexpressed proteins in pancreatic juice from pancreatic ductal adenocarcinoma patients., PMID:18706098
DJ-1 immunoreactivity in human brain astrocytes is dependent on infarct presence and infarct age., PMID:18647263
Identification of prostate cancer antigens by automated high-throughput filter immunoscreening., PMID:18045611
DJ-1 (PARK7) is associated with 3R and 4R tau neuronal and glial inclusions in neurodegenerative disorders., PMID:17719794
Selective enrichment of DJ-1 protein in primate striatal neuronal processes: implications for Parkinson's disease., PMID:17120294
PARK7 DJ-1 protects against degeneration of nigral dopaminergic neurons in Parkinson's disease rat model., PMID:16860563
For research use only. Not for human or drug use.
