Catalog No.
RHJ10602
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:20-1:100, IHC: 1:200-1:1000
Target
CPAMD7, r150, CD109, 150 kDa TGF-beta-1-binding protein, Platelet-specific Gov antigen, CD109 antigen, p180, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q6YHK3
Applications
ELISA, FCM, IF, IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3V10
Association of the human platelet antigens polymorphisms with platelet count in patients with COVID-19., PMID:38020117
CD109-regulated mechanical properties of endothelial cells., PMID:36929132
Pan-Cancer Analysis Identifies Tumor Cell Surface Targets for CAR-T Cell Therapies and Antibody Drug Conjugates., PMID:36428765
CD109 on Dendritic Cells Regulates Airway Hyperreactivity and Eosinophilic Airway Inflammation., PMID:36215676
Relationship between donor-specific HPA-15 antibodies and poor graft function in HPA-15 mismatched cord blood transplantation., PMID:35028883
A first WHO reference reagent for the detection of anti-human platelet antigen-15b., PMID:34164825
Comparative proteomics analysis for identifying the lipid metabolism related pathways in patients with Klippel-Feil syndrome., PMID:33708882
Minor impact of patient alloantibodies against human platelet antigen (HPA)-15 in the effectiveness of platelet transfusion: A pilot study., PMID:33166416
Application of lyophilised human platelets for antibody detection in solid phase red cell adherence assay., PMID:32941887
Report on the 19th International Society of Blood Transfusion Platelet Immunology Workshop 2018., PMID:32468604
High-Throughput Screening of Blood Donors for Twelve Human Platelet Antigen Systems Using Next-Generation Sequencing Reveals Detection of Rare Polymorphisms and Two Novel Protein-Changing Variants., PMID:32110192
A novel simple assay system for the detection of human platelet antigen 15 (HPA-15) alloantibodies based on three techniques: an HPA-15 expressing cell line, a monoclonal antibody-specific antigen-capture method and mixed-passive haemagglutination., PMID:31777077
CD109 regulates the inflammatory response and is required for the pathogenesis of rheumatoid arthritis., PMID:31455659
Maternal incompatibilities with fetal human platelet alloantigens -1a, -1b and -15 are the main causes of neonatal alloimmune thrombocytopenia in Russia., PMID:30701924
Development of novel monoclonal antibodies against CD109 overexpressed in human pancreatic cancer., PMID:29731998
Antibody-based cell-surface proteome profiling of metastatic breast cancer primary explants and cell lines., PMID:29498809
Reduced expression of CD109 in tumor-associated endothelial cells promotes tumor progression by paracrine interleukin-8 in hepatocellular carcinoma., PMID:27121053
Sensitive detection of platelet-specific antibodies with a modified MAIPA using biotinylated antibodies and streptavidin-coated beads., PMID:27059653
Quantitative Proteomic Verification of Membrane Proteins as Potential Therapeutic Targets Located in the 11q13 Amplicon in Cancers., PMID:26151158
Prognostic value and kinetics of circulating endothelial cells in patients with recurrent glioblastoma randomised to bevacizumab plus lomustine, bevacizumab single agent or lomustine single agent. A report from the Dutch Neuro-Oncology Group BELOB trial., PMID:26042933
The transmembrane protein Macroglobulin complement-related is essential for septate junction formation and epithelial barrier function in Drosophila., PMID:24496626
The role of alloantibodies against human platelet antigen-15 in multiply platelet transfused patients., PMID:24147542
Human platelet antigens - 2013., PMID:24102564
Prognostic value of CD109+ circulating endothelial cells in recurrent glioblastomas treated with bevacizumab and irinotecan., PMID:24069296
Expression of recombinant ITGA2 and CD109 for the detection of human platelet antigen (HPA)-5 and -15 alloantibodies., PMID:23406260
CD109, a TGF-β co-receptor, attenuates extracellular matrix production in scleroderma skin fibroblasts., PMID:22694813
The relevance of HPA-15 antigen expression for anti-HPA-15 antibody detection., PMID:21752233
Detection of antibodies against human platelet antigens 15a and 15b by using a cell line panel., PMID:20812998
Molecular insight into human platelet antigens: structural and evolutionary conservation analyses offer new perspective to immunogenic disorders., PMID:20804530
Processing of CD109 by furin and its role in the regulation of TGF-beta signaling., PMID:20101215
The first case of alloantibody against human platelet antigen-15b in Japan: possible alloimmunization by a hydatidiform mole., PMID:20030792
Identification and characterization of major proteins carrying ABO blood group antigens in the human kidney., PMID:19384157
Up-regulation of CD109 expression is associated with carcinogenesis of the squamous epithelium of the oral cavity., PMID:19016750
CD109 expression in basal-like breast carcinoma., PMID:18429827
High-level expression of CD109 is frequently detected in lung squamous cell carcinomas., PMID:17922683
Severe HPA-15b related neonatal alloimmune thrombocytopenia., PMID:17850392
CD109, a new marker for myoepithelial cells of mammary, salivary, and lacrimal glands and prostate basal cells., PMID:17493171
Neonatal alloimmune thrombocytopenia caused by human leucocyte antigen-B27 antibody., PMID:16623921
Frequency of HPA-15a and HPA-15b (Gov a/b) human platelet alloantigens in the Croatian population., PMID:16314205
Frequencies of maternal platelet alloantibodies and autoantibodies in suspected fetal/neonatal alloimmune thrombocytopenia, with emphasis on human platelet antigen-15 alloimmunization., PMID:15938738
Relevance of the HPA-15 (Gov) polymorphism on CD109 in alloimmune thrombocytopenic syndromes., PMID:15752154
A novel method for simultaneous analysis of specific platelet antibodies: SASPA., PMID:15566358
Antibody W7C5 defines a CD109 epitope expressed on CD34+ and CD34- hematopoietic and mesenchymal stem cell subsets., PMID:12799300
Antigenic profile of human thymus in concurrence with "Clusters of Thymic Epithelial Staining" classification., PMID:12725440
Heterogeneity among human bone marrow-derived mesenchymal stem cells and neural progenitor cells., PMID:12604402
Cell surface antigen CD109 is a novel member of the alpha(2) macroglobulin/C3, C4, C5 family of thioester-containing proteins., PMID:11861284
Detection of Gov system antibodies by MAIPA reveals an immunogenicity similar to the HPA-5 alloantigens., PMID:10997989
ABH antigens on human platelets: expression on the glycosyl phosphatidylinositol-anchored protein CD109., PMID:9708575
Immunologic phenotype of cultured endothelial cells: quantitative analysis of cell surface molecules., PMID:9389318
Leukocyte phenotypic changes in an in vitro model of ABO hemolytic transfusion reaction., PMID:9308635
For research use only. Not for human or drug use.
