Overview
Catalog No.
RHH99701
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
IHC: 1:100-1:200, WB: 1:500-1:1000
Target
UMP-CMP kinase 2, mitochondrial, CMPK2, Nucleoside-diphosphate kinase
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q5EBM0
Applications
IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3U91
Data Image
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IHC-P analysis of adrenal gland tissue by CMPK2 antibody (RHH99701). IHC-P was performed using sections of the formalin-fixed paraffin-embedded adrenal gland tissue;Result: Glandular cells are positively stained at the cytoplasm.
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Western blot analysis using CMPK2 mouse mAb against Jurkat lysate
References
CMPK2 is a host restriction factor that inhibits infection of multiple coronaviruses in a cell-intrinsic manner., PMID:36930652
UMP-CMP kinase 2 gene expression in macrophages is dependent on the IRF3-IFNAR signaling axis., PMID:34705862
Mitochondrial protein CMPK2 regulates IFN alpha-enhanced foam cell formation, potentially contributing to premature atherosclerosis in SLE., PMID:33874983
Association of the interferon signature metric with serological disease manifestations but not global activity scores in multiple cohorts of patients with SLE., PMID:25861459
Hepatitis E genotype 4 virus from feces of monkeys infected experimentally can be cultured in PLC/PRF/5 cells and upregulate host interferon-inducible genes., PMID:25042677
Datasheet
For research use only. Not for human or drug use.
