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Anti-SV2C Antibody (R3U79)

Catalog #:   RHH74001 Specific References (12) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: ELISA, FCM, IF, IHC
Accession: Q496J9
Overview

Catalog No.

RHH74001

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000, IHC: 1:200-1:1000

Target

SV2C, Synaptic vesicle glycoprotein 2C, KIAA1054

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q496J9

Applications

ELISA, FCM, IF, IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3U79

Data Image
  • Flow Cytometry
    Flow cytometric analysis of Raji cells using SV2C mouse mAb (green) and negative control (red).
  • Immunofluorescence
    Immunofluorescence analysis of Hela cells using SV2C mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human liver cancer tissues using SV2C mouse mAb with DAB staining.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human rectal cancer tissues using SV2C mouse mAb with DAB staining.
References

A novel single-domain antibody obtained from immune Bactrian camels against botulinum toxin type A using SPR-based screening method., PMID:40066047

Characterization of a highly neutralizing single monoclonal antibody to botulinum neurotoxin type A., PMID:33817838

In vitro potency determination of botulinum neurotoxin serotype A based on its receptor-binding and proteolytic characteristics., PMID:30016653

Immunochemical analysis of the expression of SV2C in mouse, macaque and human brain., PMID:29274878

N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A., PMID:27294781

Genetic variant predicts bevacizumab-induced hypertension in ECOG-5103 and ECOG-2100., PMID:25117820

Identification of the synaptic vesicle glycoprotein 2 receptor binding site in botulinum neurotoxin A., PMID:24583011

SNAP-23 and VAMP-3 contribute to the release of IL-6 and TNFα from a human synovial sarcoma cell line., PMID:24373201

Expression of SV2 isoforms during rodent brain development., PMID:23937191

The transcription factor Bhlhb4 is required for rod bipolar cell maturation., PMID:15363390

SV2C is a synaptic vesicle protein with an unusually restricted localization: anatomy of a synaptic vesicle protein family., PMID:10625067

SVOP, an evolutionarily conserved synaptic vesicle protein, suggests novel transport functions of synaptic vesicles., PMID:9801366

Datasheet

Document Download

Anti-SV2C Antibody (R3U79).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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For research use only. Not for human or drug use.

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Anti-SV2C Antibody (R3U79) [RHH74001]
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