Catalog No.
RHH56001
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, IF: 1:200-1:1000
Target
HLAH, HLA-H, HFE, Hereditary hemochromatosis protein
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q30201
Applications
ELISA, IF
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3U76
Array Genotyping of Transfusion Relevant Blood Cell Antigens in 6946 Ancestrally Diverse Subjects., PMID:40499009
Autoantibodies towards HFE and SYT5 in anti-neutrophil cytoplasm antibody-associated vasculitis relapse., PMID:39400561
Post-COVID Myocarditis in Patients with Primary Cardiomyopathies: Diagnosis, Clinical Course and Outcomes., PMID:39202422
IgG subclass levels in referred hemochromatosis probands with HFE p.C282Y/p.C282Y., PMID:38743659
Semaglutide-Induced Lupus Erythematosus With Multiorgan Involvement., PMID:38559525
Real-World Clinical Experience of Dupilumab in the Treatment of Chronic Palmo-Plantar Eczema in Patients with Moderate-Severe Atopic Dermatitis: 52-Week Follow-Up., PMID:37883648
Trade-off between feed efficiency and immunity in specialized high-performing chickens., PMID:37141810
Efficacy and safety of garadacimab, a factor XIIa inhibitor for hereditary angioedema prevention (VANGUARD): a global, multicentre, randomised, double-blind, placebo-controlled, phase 3 trial., PMID:36868261
In the presence of autoantibodies and iron overload, do not judge a book by its cover: A case report., PMID:35783902
Egg production, fertility, hatchability and immune responses of some chicken strains under high ambient temperatures., PMID:33387365
Chromosome 6p SNP microhaplotypes and IgG3 levels in hemochromatosis probands with HFE p.C282Y homozygosity., PMID:32623342
Protection and Safety Evaluation of Live Constructions Derived from the Pgm- and pPCP1- Yersinia pestis Strain., PMID:32098032
Prevalence and characteristics of anti-HCV positivity and chronic hepatitis C virus infection in HFE p.C282Y homozygotes., PMID:31056361
Ginseng-Related Drug-Induced Liver Injury., PMID:30186097
Screening and Identification of Peptides Specifically Targeted to Gastric Cancer Cells from a Phage Display Peptide Library., PMID:29693344
The role of TMPRSS6 and HFE variants in iron deficiency anemia in celiac disease., PMID:29194702
[Evolocumab (Repatha®) : a human monoclonal antibody against PCSK9 protein as potent cholesterol-lowering therapy]., PMID:29171950
Effects of Protein-Iron Complex Concentrate Supplementation on Iron Metabolism, Oxidative and Immune Status in Preweaning Calves., PMID:28704940
β2-Microglobulin participates in development of lung emphysema by inducing lung epithelial cell senescence., PMID:28213472
An immunohistochemical study of placental syncytiotrophoblasts in neonatal hemochromatosis., PMID:27871472
Transferrin Level Before Treatment and Genetic Polymorphism in HFE Gene as Predictive Markers for Response to Adalimumab in Crohn's Disease Patients., PMID:27115882
Critical Role of Antimicrobial Peptide Cathelicidin for Controlling Helicobacter pylori Survival and Infection., PMID:26800870
Reversal of P-gp and BCRP-mediated MDR by tariquidar derivatives., PMID:26197160
Inhibition of β2-microglobulin/hemochromatosis enhances radiation sensitivity by induction of iron overload in prostate cancer cells., PMID:23874600
[Hemochromatosis: one form of iron-overload diseases]., PMID:23853349
Structure and dynamics of drug carriers and their interaction with cellular receptors: focus on serum transferrin., PMID:23183585
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) protein-induced lysosomal translocation of proapoptotic effectors is mediated by phosphofurin acidic cluster sorting protein-2 (PACS-2)., PMID:22645134
Compartmentalization and regulation of iron metabolism proteins protect male germ cells from iron overload., PMID:22496346
Polarized distribution of heme transporters in retinal pigment epithelium and their regulation in the iron-overload disease hemochromatosis., PMID:22058337
A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield., PMID:21998254
Brain iron dysregulation and the risk of ageing white matter lesions., PMID:21979376
Differential HFE gene expression is regulated by alternative splicing in human tissues., PMID:21407826
Iron overload induces BMP6 expression in the liver but not in the duodenum., PMID:20952515
BMP6 treatment compensates for the molecular defect and ameliorates hemochromatosis in Hfe knockout mice., PMID:20682319
[Neonatal hemochromatosis: a neonate alloimmune disease]., PMID:20073397
Investigation of the distribution of lymphocyte subsets and zinc levels in multitransfused beta-thalassemia major patients., PMID:19453575
A role for the MHC class I-like Mill molecules in nutrient metabolism and wound healing., PMID:18560379
[Hereditary hemochromatosis, alpha-1-antitrypsin deficiency and Wilson's disease. Pathogenesis, clinical findings and pathways to diagnosis]., PMID:18210110
Reversible liver toxicity with adjuvant trastuzumab for localized breast cancer., PMID:18083694
Binding specificity and internalization properties of an antibody-avidin fusion protein targeting the human transferrin receptor., PMID:17884229
Alanine aminotransferase flare-up in hepatitis C virus carriers with persistently normal alanine aminotransferase levels in a hyperendemic area of Japan., PMID:17701131
Contribution of anti-cyclic citrullinated peptide antibody and rheumatoid factor to the diagnosis of arthropathy in haemochromatosis., PMID:17456529
Heterozygous beta-globin gene mutations as a risk factor for iron accumulation and liver fibrosis in chronic hepatitis C., PMID:17135308
Accelerated transferrin degradation in HFE-deficient mice is associated with increased transferrin saturation., PMID:17116709
Autoimmune liver disease., PMID:17033304
Expression and polarized localization of the hemochromatosis gene product HFE in retinal pigment epithelium., PMID:17003411
Non-transferrin-bound iron is associated with plasma level of soluble intercellular adhesion molecule-1 but not with in vivo low-density lipoprotein oxidation., PMID:16963052
Localisation of proteins of iron metabolism in the human placenta and liver., PMID:16856887
Apical distribution of HFE-beta2-microglobulin is associated with inhibition of apical iron uptake in intestinal epithelia cells., PMID:16841247
[Hepatitis C, hemochromatosis and porphyria cutanea tarda]., PMID:16555178