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Anti-HFE Antibody (R3U76)

Catalog #:   RHH56001 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: ELISA, IF
Accession: Q30201
Overview

Catalog No.

RHH56001

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, IF: 1:200-1:1000

Target

HLAH, HLA-H, HFE, Hereditary hemochromatosis protein

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q30201

Applications

ELISA, IF

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3U76

Data Image
  • Immunofluorescence
    Immunofluorescence analysis of HepG2 cells using HFE mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.
References

Array Genotyping of Transfusion Relevant Blood Cell Antigens in 6946 Ancestrally Diverse Subjects., PMID:40499009

Autoantibodies towards HFE and SYT5 in anti-neutrophil cytoplasm antibody-associated vasculitis relapse., PMID:39400561

Post-COVID Myocarditis in Patients with Primary Cardiomyopathies: Diagnosis, Clinical Course and Outcomes., PMID:39202422

IgG subclass levels in referred hemochromatosis probands with HFE p.C282Y/p.C282Y., PMID:38743659

Semaglutide-Induced Lupus Erythematosus With Multiorgan Involvement., PMID:38559525

Real-World Clinical Experience of Dupilumab in the Treatment of Chronic Palmo-Plantar Eczema in Patients with Moderate-Severe Atopic Dermatitis: 52-Week Follow-Up., PMID:37883648

Trade-off between feed efficiency and immunity in specialized high-performing chickens., PMID:37141810

Efficacy and safety of garadacimab, a factor XIIa inhibitor for hereditary angioedema prevention (VANGUARD): a global, multicentre, randomised, double-blind, placebo-controlled, phase 3 trial., PMID:36868261

In the presence of autoantibodies and iron overload, do not judge a book by its cover: A case report., PMID:35783902

Egg production, fertility, hatchability and immune responses of some chicken strains under high ambient temperatures., PMID:33387365

Chromosome 6p SNP microhaplotypes and IgG3 levels in hemochromatosis probands with HFE p.C282Y homozygosity., PMID:32623342

Protection and Safety Evaluation of Live Constructions Derived from the Pgm- and pPCP1- Yersinia pestis Strain., PMID:32098032

Prevalence and characteristics of anti-HCV positivity and chronic hepatitis C virus infection in HFE p.C282Y homozygotes., PMID:31056361

Ginseng-Related Drug-Induced Liver Injury., PMID:30186097

Screening and Identification of Peptides Specifically Targeted to Gastric Cancer Cells from a Phage Display Peptide Library., PMID:29693344

The role of TMPRSS6 and HFE variants in iron deficiency anemia in celiac disease., PMID:29194702

[Evolocumab (Repatha®) : a human monoclonal antibody against PCSK9 protein as potent cholesterol-lowering therapy]., PMID:29171950

Effects of Protein-Iron Complex Concentrate Supplementation on Iron Metabolism, Oxidative and Immune Status in Preweaning Calves., PMID:28704940

β2-Microglobulin participates in development of lung emphysema by inducing lung epithelial cell senescence., PMID:28213472

An immunohistochemical study of placental syncytiotrophoblasts in neonatal hemochromatosis., PMID:27871472

Transferrin Level Before Treatment and Genetic Polymorphism in HFE Gene as Predictive Markers for Response to Adalimumab in Crohn's Disease Patients., PMID:27115882

Critical Role of Antimicrobial Peptide Cathelicidin for Controlling Helicobacter pylori Survival and Infection., PMID:26800870

Reversal of P-gp and BCRP-mediated MDR by tariquidar derivatives., PMID:26197160

Inhibition of β2-microglobulin/hemochromatosis enhances radiation sensitivity by induction of iron overload in prostate cancer cells., PMID:23874600

[Hemochromatosis: one form of iron-overload diseases]., PMID:23853349

Structure and dynamics of drug carriers and their interaction with cellular receptors: focus on serum transferrin., PMID:23183585

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) protein-induced lysosomal translocation of proapoptotic effectors is mediated by phosphofurin acidic cluster sorting protein-2 (PACS-2)., PMID:22645134

Compartmentalization and regulation of iron metabolism proteins protect male germ cells from iron overload., PMID:22496346

Polarized distribution of heme transporters in retinal pigment epithelium and their regulation in the iron-overload disease hemochromatosis., PMID:22058337

A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield., PMID:21998254

Brain iron dysregulation and the risk of ageing white matter lesions., PMID:21979376

Differential HFE gene expression is regulated by alternative splicing in human tissues., PMID:21407826

Iron overload induces BMP6 expression in the liver but not in the duodenum., PMID:20952515

BMP6 treatment compensates for the molecular defect and ameliorates hemochromatosis in Hfe knockout mice., PMID:20682319

[Neonatal hemochromatosis: a neonate alloimmune disease]., PMID:20073397

Investigation of the distribution of lymphocyte subsets and zinc levels in multitransfused beta-thalassemia major patients., PMID:19453575

A role for the MHC class I-like Mill molecules in nutrient metabolism and wound healing., PMID:18560379

[Hereditary hemochromatosis, alpha-1-antitrypsin deficiency and Wilson's disease. Pathogenesis, clinical findings and pathways to diagnosis]., PMID:18210110

Reversible liver toxicity with adjuvant trastuzumab for localized breast cancer., PMID:18083694

Binding specificity and internalization properties of an antibody-avidin fusion protein targeting the human transferrin receptor., PMID:17884229

Alanine aminotransferase flare-up in hepatitis C virus carriers with persistently normal alanine aminotransferase levels in a hyperendemic area of Japan., PMID:17701131

Contribution of anti-cyclic citrullinated peptide antibody and rheumatoid factor to the diagnosis of arthropathy in haemochromatosis., PMID:17456529

Heterozygous beta-globin gene mutations as a risk factor for iron accumulation and liver fibrosis in chronic hepatitis C., PMID:17135308

Accelerated transferrin degradation in HFE-deficient mice is associated with increased transferrin saturation., PMID:17116709

Autoimmune liver disease., PMID:17033304

Expression and polarized localization of the hemochromatosis gene product HFE in retinal pigment epithelium., PMID:17003411

Non-transferrin-bound iron is associated with plasma level of soluble intercellular adhesion molecule-1 but not with in vivo low-density lipoprotein oxidation., PMID:16963052

Localisation of proteins of iron metabolism in the human placenta and liver., PMID:16856887

Apical distribution of HFE-beta2-microglobulin is associated with inhibition of apical iron uptake in intestinal epithelia cells., PMID:16841247

[Hepatitis C, hemochromatosis and porphyria cutanea tarda]., PMID:16555178

Datasheet

Document Download

Anti-HFE Antibody (R3U76).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-HFE Antibody (R3U76) [RHH56001]
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