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Anti-Drebrin 1/DBN1 Antibody (R3U45)

Catalog #:   RHH32902 Specific References (21) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: IHC, IP, WB
Accession: Q16643
Overview

Catalog No.

RHH32902

Species reactivity

Human, Mouse, Rat

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

IHC: 1:100-1:200, IP: 1:100-1:200, WB: 1:500-1:1000

Target

D0S117E, DBN1, Developmentally-regulated brain protein, Drebrin

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q16643

Applications

IHC, IP, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3U45

Data Image
  • Immunohistochemical
    IHC-P analysis of brain tissue by DBN1 antibody (RHH32902). IHC-P was performed using sections of the formalin-fixed paraffin-embedded brain tissue;Result: Neuropil is positively stained.
  • Immunoprecipitation
    Lane 1: Mouse brain tissue lysate ; Lane 2: DBN1 immunoprecipitated from mouse brain tissue lysate by RHH32902;Lane 3: The same as Lane 2 but use IgG isotype control antibody ;Result: RHH32902 can immunoprecipitate DBN1;
  • Western blot
    Lane 1: 15 µg of SH-SY5Y lysate; Lane 2: 15 µg of rat brain; Lane 3: 15 µg of mouse brain; Result: RHH32902 can detect DBN1 by Western blotting;
References

Cx45 regulation by kinases and impact of expression in heart failure., PMID:40280467

Exploring Potential Proteomic Biomarkers for Prognosis of Infective Endocarditis through Profiled Autoantibodies by an Immunomics Protein Array Technique., PMID:32990583

Drebrin expression patterns in patients with refractory temporal lobe epilepsy and hippocampal sclerosis., PMID:32662890

Assessment of NMDA receptor inhibition of phencyclidine analogues using a high-throughput drebrin immunocytochemical assay., PMID:31082488

Pre-plaque conformational changes in Alzheimer's disease-linked Aβ and APP., PMID:28287086

Endothelin A receptor activation on mesangial cells initiates Alport glomerular disease., PMID:27165837

A cluster of protein kinases and phosphatases modulated in fetal Down syndrome (trisomy 21) brain., PMID:25740605

Increased tau phosphorylation and impaired brain insulin/IGF signaling in mice fed a high fat/high cholesterol diet., PMID:23703152

Neutralization of soluble, synaptotoxic amyloid β species by antibodies is epitope specific., PMID:22357853

Laminin-111 stimulates proliferation of mouse embryonic stem cells through a reduction of gap junctional intercellular communication via RhoA-mediated Cx43 phosphorylation and dissociation of Cx43/ZO-1/drebrin complex., PMID:22150760

Neurites from PC12 cells are connected to each other by synapse-like structures., PMID:20698031

Alzheimer's-associated Abeta oligomers show altered structure, immunoreactivity and synaptotoxicity with low doses of oleocanthal., PMID:19631677

Involvement of mesangial cells expressing alpha-smooth muscle actin during restorative glomerular remodeling in Thy-1.1 nephritis., PMID:16924122

Proteomic analysis of TRPC5- and TRPC6-binding partners reveals interaction with the plasmalemmal Na(+)/K(+)-ATPase., PMID:16025302

Co-localization of cytosolic phospholipase A2 and cyclooxygenase-2 in Rhesus monkey cerebellum., PMID:12941466

Coincidence in dendritic clustering and synaptic targeting of homer proteins and NMDA receptor complex proteins NR2B and PSD95 during development of cultured hippocampal neurons., PMID:12676529

A mass spectrometry-based proteomic approach for identification of serine/threonine-phosphorylated proteins by enrichment with phospho-specific antibodies: identification of a novel protein, Frigg, as a protein kinase A substrate., PMID:12239280

Drebrin, a dendritic spine protein, is manifold decreased in brains of patients with Alzheimer's disease and Down syndrome., PMID:12009525

Formation of thick, curving bundles of actin by drebrin A expressed in fibroblasts., PMID:7957662

Changes of synapse-related proteins (SVP-38 and drebrins) during development of brain in congenitally hydrocephalic HTX rats with and without early placement of ventriculoperitoneal shunt., PMID:8142282

Changes of drebrin expression in the visual cortex of the cat during development., PMID:1314351

Datasheet
$ 220
Product specifications
50 μg 220 100 μg 350

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For research use only. Not for human or drug use.

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Anti-Drebrin 1/DBN1 Antibody (R3U45) [RHH32902]
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