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Anti-DDB1 Antibody (R3U31)

Catalog #:   RHH27803 Specific References (21) DATASHEET
Host species: Mouse
Isotype: IgG2b
Applications: WB
Accession: Q16531
Overview

Catalog No.

RHH27803

Species reactivity

Human, Mouse, Rat, Monkey

Host species

Mouse

Isotype

IgG2b

Clonality

Monoclonal

Tested applications

WB: 1:500-1:1000

Target

XAP-1, XPE-binding factor, DNA damage-binding protein a, XAP1, Xeroderma pigmentosum group E-complementing protein, DDB1, XPCe, DDBa, XPE-BF, DDB p127 subunit, Damage-specific DNA-binding protein 1, UV-DDB 1, UV-damaged DNA-binding protein 1, UV-damaged DNA-binding factor, DNA damage-binding protein 1, HBV X-associated protein 1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q16531

Applications

WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.5% BSA, 0.05% Sodium Azide and 50% Glycerol.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3U31

Data Image
  • Western blot
    Western blot analysis of DDB1 in Hela, MCF-7, COS7, C6 and 3T3 lysates using DDB1 antibody.
References

STK39 inhibits antiviral immune response by inhibiting DCAF1-mediated PP2A degradation., PMID:40370558

PARG inhibition limits HCC progression and potentiates the efficacy of immune checkpoint therapy., PMID:35157958

Human Herpesvirus 6A U4 Inhibits Proteasomal Degradation of the Amyloid Precursor Protein., PMID:34878807

Ddb1 Is Essential for the Expansion of CD4+ Helper T Cells by Regulating Cell Cycle Progression and Cell Death., PMID:34526995

[Research Progress on the Mechanism and Clinical Data of Cereblon 
in Reversing the Resistance of Lung Cancer to PD-1 Antibody by T cells]., PMID:33478191

Characterization and engineering of broadly reactive monoclonal antibody against hepatitis B virus X protein that blocks its interaction with DDB1., PMID:31889135

Spatiotemporal Analysis of Hepatitis B Virus X Protein in Primary Human Hepatocytes., PMID:31167911

Regulation of the Intranuclear Distribution of the Cockayne Syndrome Proteins., PMID:30504782

A core component of the CUL4 ubiquitin ligase complexes, DDB1, regulates spermatogenesis in the Chinese mitten crab, Eriocheir sinensis., PMID:27923671

VprBP Is Required for Efficient Editing and Selection of Igκ+ B Cells, but Is Dispensable for Igλ+ and Marginal Zone B Cell Maturation and Selection., PMID:26150531

Modulation of cereblon levels by anti-myeloma agents., PMID:25860244

Cell line profiling to improve monoclonal antibody production., PMID:24249214

Regulation of nucleotide excision repair by nuclear lamin b1., PMID:23894423

Structure of a double-stranded DNA (6-4) photoproduct in complex with the 64M-5 antibody Fab., PMID:23519658

Chromoplast-specific carotenoid-associated protein appears to be important for enhanced accumulation of carotenoids in hp1 tomato fruits., PMID:23400702

5-AED enhances survival of irradiated mice in a G-CSF-dependent manner, stimulates innate immune cell function, reduces radiation-induced DNA damage and induces genes that modulate cell cycle progression and apoptosis., PMID:22843381

Modulation of NKG2D-mediated cytotoxic functions of natural killer cells by viral protein R from HIV-1 primary isolates., PMID:21957298

L2DTL/CDT2 interacts with the CUL4/DDB1 complex and PCNA and regulates CDT1 proteolysis in response to DNA damage., PMID:16861906

Electrophoretic mobility shift assays to study protein binding to damaged DNA., PMID:16673891

Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex, while BMI-1 is transiently co-localized with the centromeric region in interphase., PMID:15009096

Paramyxoviruses SV5 and HPIV2 assemble STAT protein ubiquitin ligase complexes from cellular components., PMID:12504558

Datasheet

Document Download

Anti-DDB1 Antibody (R3U31).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-DDB1 Antibody (R3U31) [RHH27803]
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