Anti-MYLK Antibody (R3T99)

Catalog No.

RHH18202

Species reactivity

Human, Mouse

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000, IHC: 1:200-1:1000, WB: 1:500-1:2000

Target

MLCK1, smMLCK, MYLK1, KRP, Kinase-related protein, MLCK, MYLK, Myosin light chain kinase, smooth muscle, Telokin

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q15746

Applications

ELISA, FCM, IF, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3T99

CT45A1-mediated MLC2 (MYL9) phosphorylation promotes natural killer cell resistance and outer cell fate in a cell-in-cell structure, potentiating the progression of microsatellite instability-high colorectal cancer., PMID:39322998

Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potential., PMID:34548480

Distinct molecular subtypes of uterine leiomyosarcoma respond differently to chemotherapy treatment., PMID:28893210

Actin depolymerisation and crosslinking join forces with myosin II to contract actin coats on fused secretory vesicles., PMID:25637593

MiRNA-155 targets myosin light chain kinase and modulates actin cytoskeleton organization in endothelial cells., PMID:24486510

Non-muscle myosin light chain kinase isoform is a viable molecular target in acute inflammatory lung injury., PMID:20139351

Document Download

Anti-MYLK Antibody (R3T99).pdf