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Anti-ELAVL1 Antibody (R3T98)

Catalog #:   RHH17302 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: IHC
Accession: Q15717
Overview

Catalog No.

RHH17302

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

IHC: 1:20-1:100

Target

ELAV-like protein 1, HuR, ELAVL1, Hu-antigen R, HUR

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q15717

Applications

IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3T98

Data Image
  • Immunohistochemical
    IHC-P analysis of testis tissue by ELAVL1 antibody (RHH17302). IHC-P was performed using sections of the formalin-fixed paraffin-embedded testis tissue;Result: Cells in seminiferous ducts are positively stained at the nuclei and cytoplasm.
References

Citrullinated IGF2BP1 promotes rheumatoid synovial aggression via increasing the mRNA stability of SEMA3D., PMID:39809921

HuR (ELAVL1) regulates the CCHFV minigenome and HAZV replication by associating with viral genomic RNA., PMID:39348382

A TRIM21-based bioPROTAC highlights the therapeutic benefit of HuR degradation., PMID:37925433

Exosomal Linc00969 induces trastuzumab resistance in breast cancer by increasing HER-2 protein expression and mRNA stability by binding to HUR., PMID:37848981

Different Genetic Signatures of Small-Cell Lung Cancer Characterize Anti-GABAB R and Anti-Hu Paraneoplastic Neurological Syndromes., PMID:37638563

Necessity of HuR/ELAVL1 for the activation-induced cytidine deaminase-dependent decrease in topoisomerase 1 in antibody diversification., PMID:37086201

The RNA binding protein human antigen R is a gatekeeper of liver homeostasis., PMID:34519101

CIRBP promotes ferroptosis by interacting with ELAVL1 and activating ferritinophagy during renal ischaemia-reperfusion injury., PMID:34114349

Assembly of Cytoplasmic Stress Granules in Placentas in Women with Preeclampsia., PMID:34101146

HuR up-regulates cell surface PD-L1 via stabilizing CMTM6 transcript in cancer., PMID:33649535

ELAVL1a is an immunocompetent protein that protects zebrafish embryos from bacterial infection., PMID:33637956

MSC-induced lncRNA AGAP2-AS1 promotes stemness and trastuzumab resistance through regulating CPT1 expression and fatty acid oxidation in breast cancer., PMID:33273726

Targeting the RNA-Binding Protein HuR Alleviates Neuroinflammation in Experimental Autoimmune Encephalomyelitis: Potential Therapy for Multiple Sclerosis., PMID:33200288

Interplay between RNA-binding protein HuR and Nox4 as a novel therapeutic target in diabetic kidney disease., PMID:32240965

Human antigen R-regulated CCL20 contributes to osteolytic breast cancer bone metastasis., PMID:28851919

Data on isoaspartylation of neuronal ELAVL proteins., PMID:27924291

Cytoplasmic HuR Status Predicts Disease-free Survival in Resected Pancreatic Cancer: A Post-hoc Analysis From the International Phase III ESPAC-3 Clinical Trial., PMID:27893535

DO-RIP-seq to quantify RNA binding sites transcriptome-wide., PMID:27840290

Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation., PMID:27595325

HuR in pheochromocytomas and paragangliomas - overexpression in verified malignant tumors., PMID:27357268

Expression of ARE-binding proteins AUF1 and HuR in follicular adenoma and carcinoma of thyroid gland., PMID:26925783

B Cell-Intrinsic Expression of the HuR RNA-Binding Protein Is Required for the T Cell-Dependent Immune Response In Vivo., PMID:26320247

The RNA-binding protein HuR is essential for the B cell antibody response., PMID:25706746

A recently evolved class of alternative 3'-terminal exons involved in cell cycle regulation by topoisomerase inhibitors., PMID:24577238

Proteome-wide characterization of the RNA-binding protein RALY-interactome using the in vivo-biotinylation-pulldown-quant (iBioPQ) approach., PMID:23614458

Cooperative role of the RNA-binding proteins Hzf and HuR in p53 activation., PMID:21402775

High-constitutive HuR phosphorylation at Ser 318 by PKC{delta} propagates tumor relevant functions in colon carcinoma cells., PMID:21310943

HuR expression is a marker of poor prognosis in renal cell carcinoma., PMID:21161467

Tandem phosphorylation of serines 221 and 318 by protein kinase Cdelta coordinates mRNA binding and nucleocytoplasmic shuttling of HuR., PMID:20086103

Melav2, an elav-like gene, is essential for spermatid differentiation in the flatworm Macrostomum lignano., PMID:19995429

Extensive association of HuR with hnRNP proteins within immunoselected hnRNP and mRNP complexes., PMID:19931428

HuR is exported to the cytoplasm in oral cancer cells in a different manner from that of normal cells., PMID:19513080

Angiotensin II induces renal plasminogen activator inhibitor-1 and cyclooxygenase-2 expression post-transcriptionally via activation of the mRNA-stabilizing factor human-antigen R., PMID:19246637

Phosphorylation of the HuR ligand APRIL by casein kinase 2 regulates CD83 expression., PMID:19130553

Posttranscriptional regulation of the breast cancer susceptibility gene BRCA1 by the RNA binding protein HuR., PMID:19010922

Enhancement of p53 expression in keratinocytes by the bioflavonoid apigenin is associated with RNA-binding protein HuR., PMID:18680106

Nuclear HuR accumulation through phosphorylation by Cdk1., PMID:18593881

UVB irradiation regulates Cox-2 mRNA stability through AMPK and HuR in human keratinocytes., PMID:18449856

Novel tyrosine phosphorylated and cardiolipin-binding protein CLPABP functions as mitochondrial RNA granule., PMID:18191643

Expression of HuR in Merkel cell carcinoma and in normal skin., PMID:18095988

Effects of infliximab therapy on gene expression levels of tumor necrosis factor alpha, tristetraprolin, T cell intracellular antigen 1, and Hu antigen R in patients with rheumatoid arthritis., PMID:17599736

Analysis of nucleocytoplasmic trafficking of the HuR ligand APRIL and its influence on CD83 expression., PMID:17178712

Early exposure to IL-4 stabilizes IL-4 mRNA in CD4+ T cells via RNA-binding protein HuR., PMID:16982877

Prognostic significance of cyclin A in gastric cancer., PMID:16708383

Translational control of cytochrome c by RNA-binding proteins TIA-1 and HuR., PMID:16581801

Expression of CD83 is regulated by HuR via a novel cis-active coding region RNA element., PMID:16484227

Cyclooxygenase-2 is an independent prognostic factor in gastric cancer and its expression is regulated by the messenger RNA stability factor HuR., PMID:16243808

The Xenopus ELAV protein ElrB represses Vg1 mRNA translation during oogenesis., PMID:16199879

New horizons for VEGF. Is there a role for nuclear localization?, PMID:15707649

Evidence for reassociation of RNA-binding proteins after cell lysis: implications for the interpretation of immunoprecipitation analyses., PMID:15388877

Datasheet

Document Download

Anti-ELAVL1 Antibody (R3T98).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-ELAVL1 Antibody (R3T98) [RHH17302]
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