Catalog No.
RHH11501
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IHC: 1:200-1:1000
Target
CT22, SPA17, Sp17-1, SP17, Cancer/testis antigen 22, Sperm surface protein Sp17, Sperm autoantigenic protein 17, Sperm protein 17
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q15506
Applications
ELISA, FCM, IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3T83
Sperm protein antigen 17 and Sperm flagellar 1 cancer testis antigens are expressed in a rare case of ciliated foregut cyst of the common hepatic duct., PMID:37224658
Serum Sp17 Autoantibody Serves as a Potential Specific Biomarker in Patients with SAPHO Syndrome., PMID:33392854
Immunogenicity and contraceptive efficacy of recombinant fusion protein encompassing Sp17 spermatozoa-specific protein and GnRH: Relevance of adjuvants and microparticles based delivery to minimize number of injections., PMID:31845450
Cancer-testis antigens as biomarkers for Merkel cell carcinoma: Pitfalls and opportunities., PMID:31218705
Validity and prognostic significance of sperm protein 17 as a tumor biomarker for epithelial ovarian cancer: a retrospective study., PMID:30309325
Novel Sperm and Gonadotropin-releasing Hormone-based Recombinant Fusion Protein: Achievement of 100% Contraceptive Efficacy by Co-immunization of Male and Female Mice., PMID:27676172
Mapping T and B cell epitopes in sperm protein 17 to support the development of an ovarian cancer vaccine., PMID:26263201
Novel antigens in non-small cell lung cancer: SP17, AKAP4, and PTTG1 are potential immunotherapeutic targets., PMID:25739119
Increased levels of sperm protein 17 mRNA and circulating antibodies in periampullary carcinoma patients., PMID:25348194
Anti-Sp17 monoclonal antibody-doxorubicin conjugates as molecularly targeted chemotherapy for ovarian carcinoma., PMID:23943313
Sperm protein 17, MAGE-C1 and NY-ESO-1 in hepatocellular carcinoma: expression frequency and their correlation with clinical parameters., PMID:23923079
Anti-Sp17 monoclonal antibody with antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity activities against human ovarian cancer cells., PMID:22198696
In vivo molecular targeting effects of anti-Sp17- ICG-Der-02 on hepatocellular carcinoma evaluated by an optical imaging system., PMID:21366930
Sperm protein 17 is highly expressed in endometrial and cervical cancers., PMID:20712874
[Biological activity assays and cellular imaging of anti-human sperm protein 17 immunomagnetic nanoparticles]., PMID:19900363
A yeast two-hybrid system using Sp17 identified Ropporin as a novel cancer-testis antigen in hematologic malignancies., PMID:17551920
[Detection of anti-Sp17 antibodies in infertile patients' serum and its clinical significance]., PMID:17302030
Clinical significance of sperm protein 17 expression and immunogenicity in esophageal cancer., PMID:17230514
[Preparation and characterization of the monoclonal antibody against human sperm protein 17]., PMID:16948914
[Development of radioimmunoassay for human sperm protein 17]., PMID:16833189
Changes in intracellular distribution and activity of protein phosphatase PP1gamma2 and its regulating proteins in spermatozoa lacking AKAP4., PMID:15385410
Association of sperm protein 17 with A-kinase anchoring protein 3 in flagella., PMID:15257753
Expression of sperm protein 17 (Sp17) in ovarian cancer., PMID:14712480
Tumor vaccine for ovarian carcinoma targeting sperm protein 17., PMID:12015770
Sperm protein 17 is not expressed on normal leukocytes., PMID:12001904
Sperm protein 17 is expressed on normal and malignant lymphocytes and promotes heparan sulfate-mediated cell-cell adhesion., PMID:11568003
Sperm protein 17 (Sp17) in multiple myeloma: opportunity for myeloma-specific donor T cell infusion to enhance graft-versus-myeloma effect without increasing graft-versus-host disease risk., PMID:11477539
Sperm protein 17 is a novel cancer-testis antigen in multiple myeloma., PMID:11222401
A chimeric sperm peptide induces antibodies and strain-specific reversible infertility in mice., PMID:9716550
Immune response to immunization with sperm antigens in the macaque oviduct., PMID:9510968
Sequence and characterization of the sperm protein Sp17 from the baboon., PMID:9110316
Autoimmunogenicity of the human sperm protein Sp17 in vasectomized men and identification of linear B cell epitopes., PMID:9022615
Sequence and localization of the mouse sperm autoantigenic protein, Sp17., PMID:7578682
Sequence of a rabbit sperm zona pellucida binding protein and localization during the acrosome reaction., PMID:7525387
For research use only. Not for human or drug use.
