Catalog No.
RHH08103
Species reactivity
Human, Mouse, Rat
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
IHC: 1:100-1:200, IP: 1:100-1:200, WB: 1:500-1:1000
Target
Mitochondrial 20 kDa outer membrane protein, Mitochondrial import receptor subunit TOM20 homolog, KIAA0016, TOMM20, Outer mitochondrial membrane receptor Tom20
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q15388
Applications
IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3T69
Inactivation of SIAH-1 E3 ligase attenuates Aβ toxicity by suppressing ubiquitin-dependent DVE-1 degradation in Caenorhabditis elegans models of Alzheimer's disease., PMID:40349774
NLRP3 inflammasome inhibits mitophagy during the progression of temporal lobe epilepsy., PMID:40348802
Senecavirus A induces mitophagy to promote self-replication through direct interaction of 2C protein with K27-linked ubiquitinated TUFM catalyzed by RNF185., PMID:38084826
Tissue imaging reveals disruption of epithelial mitochondrial networks and loss of mitochondria-associated cytochrome-C in inflamed human and murine colon., PMID:36356719
Fibroblast-epithelial metabolic coupling in laryngeal cancer., PMID:36327815
Lens Aquaporin-5 Inserts Into Bovine Fiber Cell Plasma Membranes Via Unconventional Protein Secretion., PMID:35816045
Generation of an Ihh-mKate2-Dre knock-in mouse line., PMID:35765931
Flow Cytometric Analysis of Multiple Mitochondrial Parameters in Human Induced Pluripotent Stem Cells and Their Neural and Glial Derivatives., PMID:34806709
BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the differentiation of optic nerve oligodendrocytes., PMID:33404293
Raft-like lipid microdomains drive autophagy initiation via AMBRA1-ERLIN1 molecular association within MAMs., PMID:33034545
The AMPK-MFN2 axis regulates MAM dynamics and autophagy induced by energy stresses., PMID:32249716
Increased number of mitochondria in capillaries distributed in stroke-like lesions of two patients with MELAS., PMID:31408922
Post-embedding Mammalian Tissue for Immunoelectron Microscopy: A Standardized Procedure Based on Heat-Induced Antigen Retrieval., PMID:27515088
Engineered Upconversion Nanoparticles for Resolving Protein Interactions inside Living Cells., PMID:27510808
Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease., PMID:27503909
Spatial profiles of markers of glycolysis, mitochondria, and proton pumps in a rat glioma suggest coordinated programming for proliferation., PMID:26032618
A reverse Warburg metabolism in oral squamous cell carcinoma is not dependent upon myofibroblasts., PMID:25420473
Immunocytochemical localization of the translocase of the outer mitochondrial membrane (Tom20) in the human cochlea., PMID:23165776
Interaction between the human mitochondrial import receptors Tom20 and Tom70 in vitro suggests a chaperone displacement mechanism., PMID:21771790
TOM22, a core component of the mitochondria outer membrane protein translocation pore, is a mitochondrial receptor for the proapoptotic protein Bax., PMID:17096026
Voltage-dependent anion channel localises to the plasma membrane and peripheral but not perinuclear mitochondria., PMID:12698369
Tom34 unlike Tom20 does not interact with the leader sequences of mitochondrial precursor proteins., PMID:11913975
Characterization of the novel mitochondrial protein import component, Tom34, in mammalian cells., PMID:10101285
Characterization of the initial steps of precursor import into rat liver mitoplasts., PMID:9756630
Interactions of the human mitochondrial protein import receptor, hTom20, with precursor proteins in vitro reveal pleiotropic specificities and different receptor domain requirements., PMID:9211931
A receptor for the import of proteins into human mitochondria., PMID:8654425
Identification of the human mitochondrial protein import receptor, huMas20p. Complementation of delta mas20 in yeast., PMID:7589431