Catalog No.
RHG99501
Species reactivity
Human, Mouse, Monkey
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
IF: 1:200-1:1000, WB: 1:500-1:2000
Target
H3-K9-HMTase 4, ESET, SETDB1, SET domain bifurcated 1, Histone H3-K9 methyltransferase 4, KMT1E, KIAA0067, Lysine N-methyltransferase 1E, ERG-associated protein with SET domain, Histone-lysine N-methyltransferase SETDB1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q15047
Applications
IF, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3T51
H3K14ac facilitates the reinstallation of constitutive heterochromatin in Drosophila early embryos by engaging Eggless/SetDB1., PMID:39437264
Genome-Wide CRISPR/Cas9 Screening Unveils a Novel Target ATF7IP-SETDB1 Complex for Enhancing Difficult-to-Express Protein Production., PMID:38240694
SETDB1-mediated CD147-K71 di-methylation promotes cell apoptosis in non-small cell lung cancer., PMID:37692516
Targeting intracellular proteins with cell type-specific functions for cancer immunotherapy., PMID:39872303
Nuclear AREG affects a low-proliferative phenotype and contributes to drug resistance of melanoma., PMID:36054710
Epigenetic comparison of CHO hosts and clones reveals divergent methylation and transcription patterns across lineages., PMID:35028935
Immunochemical Detection of Modified Cytosine Species in Mammalian Preimplantation Embryos., PMID:32822029
Blocking histone methyltransferase SETDB1 inhibits tumorigenesis and enhances cetuximab sensitivity in colorectal cancer., PMID:32473242
Application of dual reading domains as novel reagents in chromatin biology reveals a new H3K9me3 and H3K36me2/3 bivalent chromatin state., PMID:28946896
Subsets of Visceral Adipose Tissue Nuclei with Distinct Levels of 5-Hydroxymethylcytosine., PMID:27171244
Analysis of the subcellular localization of the human histone methyltransferase SETDB1., PMID:26296461
The histone methyltransferase ESET is required for the survival of spermatogonial stem/progenitor cells in mice., PMID:24763053
Roles of histone H3K9 methyltransferases during Drosophila spermatogenesis., PMID:22476432
Characterization of HIV Tat modifications using novel methyl-lysine-specific antibodies., PMID:20615470
SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins., PMID:11959841
For research use only. Not for human or drug use.
