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Anti-SUZ12 Antibody (R3T47)

Catalog #:   RHG97902 Specific References (20) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: IHC
Accession: Q15022
Overview

Catalog No.

RHG97902

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

IHC: 1:200-1:1000

Target

SUZ12, Polycomb protein SUZ12, Joined to JAZF1 protein, CHET9, KIAA0160, ChET 9 protein, Suppressor of zeste 12 protein homolog, Chromatin precipitated E2F target 9 protein, JJAZ1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q15022

Applications

IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3T47

Data Image
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human kidney convoluted tubule tissues (left) and esophageal cancer tissues (right) using SUZ12 mouse mAb with DAB staining.
References

Loss of Histone H3K27 Trimethylation (H3K27me3) Expression as a Potential Diagnostic Pitfall in Sarcomatoid Carcinoma., PMID:37997394

Interplay between desmoglein2 and hypoxia controls metastasis in breast cancer., PMID:33431674

Dual targeting of EZH2 and androgen receptor as a novel therapy for castration-resistant prostate cancer., PMID:32805266

WT1 influences apoptosis and proliferation of immature mice granular cells through regulation of the wnt/β-catenin signal pathway., PMID:31880532

PRC2 Facilitates the Regulatory Topology Required for Poised Enhancer Function during Pluripotent Stem Cell Differentiation., PMID:28285903

Loss of H3K27me3 Expression Is a Highly Sensitive Marker for Sporadic and Radiation-induced MPNST., PMID:26645727

Generation of an anti-EpCAM antibody and epigenetic regulation of EpCAM in colorectal cancer., PMID:25652097

Molecular characterization of a population-based series of endometrial stromal sarcomas in Kuwait., PMID:25288234

Frequent expression of KIT in endometrial stromal sarcoma with YWHAE genetic rearrangement., PMID:24186140

Pharmacological inhibition of polycomb repressive complex-2 activity induces apoptosis in human colon cancer stem cells., PMID:23588203

Polycomb repressive complex 2 targets murine cytomegalovirus chromatin for modification and associates with viral replication centers., PMID:22279536

Human long non-coding RNAs promote pluripotency and neuronal differentiation by association with chromatin modifiers and transcription factors., PMID:22193719

Quantitative mass spectrometry of histones H3.2 and H3.3 in Suz12-deficient mouse embryonic stem cells reveals distinct, dynamic post-translational modifications at Lys-27 and Lys-36., PMID:20150217

Epithelial cell adhesion molecule regulation is associated with the maintenance of the undifferentiated phenotype of human embryonic stem cells., PMID:20064925

SUZ12 is a candidate target of the non-canonical WNT pathway in the progression of chronic myeloid leukemia., PMID:19847889

CTCF regulates allelic expression of Igf2 by orchestrating a promoter-polycomb repressive complex 2 intrachromosomal loop., PMID:18662993

Early loss of Xist RNA expression and inactive X chromosome associated chromatin modification in developing primordial germ cells., PMID:17848991

Suz12 binds to silenced regions of the genome in a cell-type-specific manner., PMID:16751344

An improved cloning strategy for chromatin-immunoprecipitation-derived DNA fragments., PMID:16647032

The murine polycomb group protein Eed is required for global histone H3 lysine-27 methylation., PMID:15916951

Datasheet

Document Download

Anti-SUZ12 Antibody (R3T47).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

Contact Information

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For research use only. Not for human or drug use.

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Anti-SUZ12 Antibody (R3T47) [RHG97902]
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