Catalog No.
RHG81001
Species reactivity
Human, Rat
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000, WB: 1:500-1:2000
Target
CRK-associated substrate-related protein, Neural precursor cell expressed developmentally down-regulated protein 9, Enhancer of filamentation 1, CASL, CASS2, NEDD-9, CAS-L, CasL, hEF1, NEDD9, Cas scaffolding protein family member 2, Renal carcinoma antigen NY-REN-12, p105
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q14511
Applications
ELISA, FCM, IF, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3T24
Two prospective, multicenter studies for the identification of biomarker signatures for early detection of pulmonary hypertension (PH): The CIPHER and CIPHER-MRI studies., PMID:38868397
NEDD9 Is a Novel and Modifiable Mediator of Platelet-Endothelial Adhesion in the Pulmonary Circulation., PMID:33523764
Prognostic Significances of NEDD-9 and FOXL-1 Expression in Intestinal Type Gastric Carcinoma: an Immunohistochemical Study., PMID:32794109
The role of neural precursor cell-expressed developmentally down-regulated protein 9 in predicting bacillus Calmette-Guerin response in nonmuscle invasive bladder cancer., PMID:29519561
Autoantibody Profiling of Glioma Serum Samples to Identify Biomarkers Using Human Proteome Arrays., PMID:26370624
A New Versatile Immobilization Tag Based on the Ultra High Affinity and Reversibility of the Calmodulin-Calmodulin Binding Peptide Interaction., PMID:26159704
The role of Cas-L/NEDD9 as a regulator of collagen-induced arthritis in a murine model., PMID:25847598
Immunohistochemistry-based prognostic biomarkers in NSCLC: novel findings on the road to clinical use?, PMID:25599124
Role for chondroitin sulfate glycosaminoglycan in NEDD9-mediated breast cancer cell growth., PMID:25445787
Issues in interpreting the in vivo activity of Aurora-A., PMID:25384454
The N-end rule pathway counteracts cell death by destroying proapoptotic protein fragments., PMID:22670058
The aryl hydrocarbon receptor regulates focal adhesion sites through a non-genomic FAK/Src pathway., PMID:22665056
SHEP1 partners with CasL to promote marginal zone B-cell maturation., PMID:20956287
Enhanced genetic instability and dasatinib sensitivity in mammary tumor cells lacking NEDD9., PMID:20940402
Human enhancer of filamentation 1 Is a mediator of hypoxia-inducible factor-1alpha-mediated migration in colorectal carcinoma cells., PMID:20442290
Interferon-inducible factor 16 is a novel modulator of glucocorticoid action., PMID:20086048
Differential gene expression triggered by highly cytotoxic alpha-emitter-immunoconjugates in gastric cancer cells., PMID:19139817
Crk-associated substrate (Cas) family member, NEDD9, is regulated in human neuroblastoma cells and in the embryonic hindbrain by all-trans retinoic acid., PMID:15376324
Glucose stimulates the tyrosine phosphorylation of Crk-associated substrate in pancreatic beta-cells., PMID:12746446
The GDP exchange factor AND-34 is expressed in B cells, associates with HEF1, and activates Cdc42., PMID:12517963
Distinctive signaling pathways through CD82 and beta1 integrins in human T cells., PMID:11981820
Lymphocyte binding to MAdCAM-1 via alpha4beta7 integrin activates a signal transduction pathway involving tyrosine phosphorylation of paxillin and p105(Cas-L)., PMID:11947929
Dissection of HEF1-dependent functions in motility and transcriptional regulation., PMID:11801728
Chat, a Cas/HEF1-associated adaptor protein that integrates multiple signaling pathways., PMID:10692442
Tyrosine phosphorylation of Crk-associated substrate lymphocyte-type is a critical element in TCR- and beta 1 integrin-induced T lymphocyte migration., PMID:10490968
Fyn and Lck tyrosine kinases regulate tyrosine phosphorylation of p105CasL, a member of the p130Cas docking protein family, in T-cell receptor-mediated signalling., PMID:10447714
T cell receptor-mediated tyrosine phosphorylation of Cas-L, a 105-kDa Crk-associated substrate-related protein, and its association of Crk and C3G., PMID:9497377
Association of the Cas-like molecule HEF1 with CrkL following integrin and antigen receptor signaling in human B-cells: potential relevance to neoplastic lymphohematopoietic cells., PMID:9498705
Involvement of p130(Cas) and p105(HEF1), a novel Cas-like docking protein, in a cytoskeleton-dependent signaling pathway initiated by ligation of integrin or antigen receptor on human B cells., PMID:9020138
For research use only. Not for human or drug use.
