Catalog No.
RHG80202
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IHC: 1:200-1:1000, WB: 1:500-1:2000
Target
BECN1, Beclin-1, Coiled-coil myosin-like BCL2-interacting protein, Protein GT197, GT197
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q14457
Applications
ELISA, FCM, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3T23
Rituximab-Chidamide combination chemotherapy enhances autophagy to overcome drug resistance in diffuse large B-cell lymphoma., PMID:40258315
Renal Expression Levels of C5a Receptor and Autophagy-related Beclin-1 and LC3A/B Are Simultaneously Enhanced Under Immunoglobulin Treatment in a Rat Model of Sepsis., PMID:40010959
Autophagy-activating aluminum hydroxide nanovaccine for enhanced antigen presentation and anti-tumor immunity., PMID:39547420
Avian TRIM13 attenuates antiviral innate immunity by targeting MAVS for autophagic degradation., PMID:39508267
Tumor cell-released autophagosomes (TRAPs) induce PD-L1-decorated NETs that suppress T-cell function to promote breast cancer pulmonary metastasis., PMID:38926151
Does Autophagy have a Role in the Pathogenesis of Pediatric Hepatic Steatosis?, PMID:38809648
VHL suppresses autophagy and tumor growth through PHD1-dependent Beclin1 hydroxylation., PMID:38360997
The expression of autophagy markers in IVIG-resistant Kawasaki disease and the establishment of prediction model., PMID:38114939
Senecavirus A induces mitophagy to promote self-replication through direct interaction of 2C protein with K27-linked ubiquitinated TUFM catalyzed by RNF185., PMID:38084826
Comparison of the Effects of Recombinant and Native Prolactin on the Proliferation and Apoptosis of Goose Granulosa Cells., PMID:38003565
Tumor-derived lactate promotes resistance to bevacizumab treatment by facilitating autophagy enhancer protein RUBCNL expression through histone H3 lysine 18 lactylation (H3K18la) in colorectal cancer., PMID:37615625
Autophagy and mitophagy-related extracellular mitochondrial dysfunction of cerebrospinal fluid cells in patients with hemorrhagic moyamoya disease., PMID:37612316
Homocysteine metabolites inhibit autophagy, elevate amyloid beta, and induce neuropathy by impairing Phf8/H4K20me1-dependent epigenetic regulation of mTOR in cystathionine β-synthase-deficient mice., PMID:37477632
The biomechanistic aspects of renal cortical injury induced by diesel exhaust particles in rats and the renoprotective contribution of quercetin pretreatment: Histological and biochemical study., PMID:34751495
Selenium inhibits growth of trastuzumab-resistant human breast cancer cells via downregulation of Akt and beclin-1., PMID:34525121
Apelin/APJ signaling activates autophagy to promote human lung adenocarcinoma cell migration., PMID:34186050
Bioactive peptide isolated from sesame seeds inhibits cell proliferation and induces apoptosis and autophagy in leukemic cells., PMID:33907539
Integrated Transcriptomic and Epigenetic Study of PCOS: Impact of Map3k1 and Map1lc3a Promoter Methylation on Autophagy., PMID:33763111
Platelet autophagic machinery involved in thrombosis through a novel linkage of AMPK-MTOR to sphingolipid metabolism., PMID:33749503
Beclin1‑armed oncolytic Vaccinia virus enhances the therapeutic efficacy of R‑CHOP against lymphoma in vitro and in vivo., PMID:33469679
BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the differentiation of optic nerve oligodendrocytes., PMID:33404293
Abolishing UCHL1's hydrolase activity exacerbates TBI-induced axonal injury and neuronal death in mice., PMID:33159930
HIV-1 Env induces pexophagy and an oxidative stress leading to uninfected CD4+ T cell death., PMID:33073673
Raft-like lipid microdomains drive autophagy initiation via AMBRA1-ERLIN1 molecular association within MAMs., PMID:33034545
TSPAN1 promotes autophagy flux and mediates cooperation between WNT-CTNNB1 signaling and autophagy via the MIR454-FAM83A-TSPAN1 axis in pancreatic cancer., PMID:32972302
Beclin1 Binds to Enterovirus 71 3D Protein to Promote the Virus Replication., PMID:32674313
PKD2/polycystin-2 induces autophagy by forming a complex with BECN1., PMID:32543276
Autophagy coupled to translation is required for long-term memory., PMID:32501746
Reduced-Beclin1-Expressing Mice Infected with Zika-R103451 and Viral-Associated Pathology during Pregnancy., PMID:32498399
Vaccine adjuvant activity of a TLR4-activating synthetic glycolipid by promoting autophagy., PMID:32439945
Treatment of breast cancer with autophagy inhibitory microRNAs carried by AGO2-conjugated nanoparticles., PMID:32345308
The AMPK-MFN2 axis regulates MAM dynamics and autophagy induced by energy stresses., PMID:32249716
EHMT2/G9a Inhibits Aortic Smooth Muscle Cell Death by Suppressing Autophagy Activation., PMID:32174799
Autophagy-based unconventional secretion of HMGB1 by keratinocytes plays a pivotal role in psoriatic skin inflammation., PMID:32019420
Binding of Avibirnavirus VP3 to the PIK3C3-PDPK1 complex inhibits autophagy by activating the AKT-MTOR pathway., PMID:31885313
Disruptions of Autophagy in the Rat Retina with Age During the Development of Age-Related-Macular-Degeneration-like Retinopathy., PMID:31569675
Autophagy promotes citrullination of VIM (vimentin) and its interaction with major histocompatibility complex class II in synovial fibroblasts., PMID:31486697
Autophagy precedes apoptosis during degeneration of the Kölliker's organ in the development of rat cochlea., PMID:31189296
Unconventional Secretion of Adipocyte Fatty Acid Binding Protein 4 Is Mediated By Autophagic Proteins in a Sirtuin-1-Dependent Manner., PMID:31171562
Nutrient deprivation and lysosomal stress induce activation of TFEB in retinal pigment epithelial cells., PMID:31160892
Predictive and prognostic implications of 4E-BP1, Beclin-1, and LC3 for cetuximab treatment combined with chemotherapy in advanced colorectal cancer with wild-type KRAS: Analysis from real-world data., PMID:31057298
LC3A, LC3B and Beclin-1 Expression in Gastric Cancer., PMID:30504397
Annexin A1-suppressed autophagy promotes nasopharyngeal carcinoma cell invasion and metastasis by PI3K/AKT signaling activation., PMID:30459351
Tumor Sidedness and Enriched Gene Groups for Efficacy of First-line Cetuximab Treatment in Metastatic Colorectal Cancer., PMID:30275242
ATG5 is required for B cell polarization and presentation of particulate antigens., PMID:30196744
The tumor suppressor LKB1 regulates starvation-induced autophagy under systemic metabolic stress., PMID:28779098
Differential regulation of cell death pathways by the microenvironment correlates with chemoresistance and survival in leukaemia., PMID:28582465
Autophagy Is an Innate Mechanism Associated with Leprosy Polarization., PMID:28056107
Receptor for advanced glycation end product blockade enhances the chemotherapeutic effect of cisplatin in tongue squamous cell carcinoma by reducing autophagy and modulating the Wnt pathway., PMID:27831944
[Effect of Xinfeng Capsule on AS Patients and Their Serum Immunoglobulin Subtypes and Peripheral Lymphocyte Autophagy]., PMID:27236888
For research use only. Not for human or drug use.
