Catalog No.
RHG66301
Species reactivity
Human
Host species
Mouse
Isotype
IgG2b
Clonality
Monoclonal
Tested applications
WB: 1:500-1:2000
Target
Protein-tyrosine kinase 6, BRK, PTK6, Breast tumor kinase, Tyrosine-protein kinase BRK
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q13882
Applications
WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3T01
High heterogeneity of cross-reactive immunoglobulins in multiple sclerosis presumes combining of B-cell epitopes for diagnostics: a case-control study., PMID:39669579
Molecular features and clinical implications of the heterogeneity in Chinese patients with HER2-low breast cancer., PMID:37607916
CD147 monoclonal antibody attenuates abdominal aortic aneurysm formation in angiotensin II-Infused apoE-/- mice., PMID:37393837
Kinase activity profiling reveals contribution of G-protein signaling modulator 2 deficiency to impaired regulatory T cell migration in rheumatoid arthritis., PMID:34555678
Effects of simultaneous knockdown of HER2 and PTK6 on malignancy and tumor progression in human breast cancer cells., PMID:23364537
Brk/PTK6 sustains activated EGFR signaling through inhibiting EGFR degradation and transactivating EGFR., PMID:22231447
Detection of Brk expression in non-small cell lung cancer: clinicopathological relevance., PMID:21603980
Breast tumor kinase and extracellular signal-regulated kinase 5 mediate Met receptor signaling to cell migration in breast cancer cells., PMID:20687930
PTK6 regulates IGF-1-induced anchorage-independent survival., PMID:20668531
PTK6 inhibits down-regulation of EGF receptor through phosphorylation of ARAP1., PMID:20554524
STAP-2 is phosphorylated at tyrosine-250 by Brk and modulates Brk-mediated STAT3 activation., PMID:19393627
Breast tumor kinase BRK requires kinesin-2 subunit KAP3A in modulation of cell migration., PMID:18077133
Signal transducer and activator of transcription 5b: a new target of breast tumor kinase/protein tyrosine kinase 6., PMID:17997837
Tyrosine phosphorylation of sam68 by breast tumor kinase regulates intranuclear localization and cell cycle progression., PMID:16179349
Role of breast tumour kinase in the in vitro differentiation of HaCaT cells., PMID:16086737
Regulated association of protein kinase B/Akt with breast tumor kinase., PMID:15539407
Characterization of the 5'-flanking region of the human PTK6 gene., PMID:11997104
BRK tyrosine kinase expression in a high proportion of human breast carcinomas., PMID:9266966
For research use only. Not for human or drug use.
