Catalog No.
RHG64802
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400
Target
Immediate-early-response protein APR, NOXA, PMA-induced protein 1, PMAIP1, Protein Noxa, Phorbol-12-myristate-13-acetate-induced protein 1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q13794
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3S95
Early B cell transcriptomic markers of measles-specific humoral immunity following a 3rd dose of MMR vaccine., PMID:38633249
Isothiocyanate groups of 4,4'-diisothiocyanatostilbene-2,2'-disulfonate (DIDS) inhibit cell penetration of octa-arginine (R8)-fused peptides., PMID:31852026
From lipid locus to drug target through human genomics., PMID:29800275
Designing a cancer therapeutic peptide by combining the mitochondrial targeting domain of Noxa and ErbB2-targeting moieties., PMID:29193033
Repression of Mcl-1 and disruption of the Mcl-1/Bak interaction in myeloma cells couple ER stress to mitochondrial apoptosis., PMID:27697610
Chronic lymphocytic leukemia development is accelerated in mice with deficiency of the pro-apoptotic regulator NOXA., PMID:27479816
Necrosis-inducing peptide has the beneficial effect on killing tumor cells through neuropilin (NRP-1) targeting., PMID:27083053
Use of Anti-Noxa Antibody for Differential Diagnosis between Epithelioid Mesothelioma and Reactive Mesothelial Hyperplasia., PMID:26735863
Cyclin-Dependent Kinase Inhibitor P1446A Induces Apoptosis in a JNK/p38 MAPK-Dependent Manner in Chronic Lymphocytic Leukemia B-Cells., PMID:26606677
BCR-signaling-induced cell death demonstrates dependency on multiple BH3-only proteins in a murine model of B-cell lymphoma., PMID:26184912
One siRNA pool targeting the λ constant region stops λ light-chain production and causes terminal endoplasmic reticulum stress., PMID:24723680
Mcl-1 dependence predicts response to vorinostat and gemtuzumab ozogamicin in acute myeloid leukemia., PMID:24636337
Pro-apoptotic TP53 homolog TAp63 is repressed via epigenetic silencing and B-cell receptor signalling in chronic lymphocytic leukaemia., PMID:24117128
The BH3-only protein Puma plays an essential role in p53-mediated apoptosis of chronic lymphocytic leukemia cells., PMID:23517560
Toward personalized therapy for chronic lymphocytic leukemia: DSC and cDNA microarray assessment of two cases., PMID:23114648
Up-regulation of fas and fasL pro-apoptotic genes expression in type 1 diabetes patients after autologous haematopoietic stem cell transplantation., PMID:22519592
ON 01910.Na is selectively cytotoxic for chronic lymphocytic leukemia cells through a dual mechanism of action involving PI3K/AKT inhibition and induction of oxidative stress., PMID:22351695
BH3-only protein Noxa regulates apoptosis in activated B cells and controls high-affinity antibody formation., PMID:22144184
Apoptosis induced by mammalian reovirus is beta interferon (IFN) independent and enhanced by IFN regulatory factor 3- and NF-κB-dependent expression of Noxa., PMID:22090144
Mechanisms of apoptosis on human lens epithelium after ultraviolet light exposure., PMID:21655046
Distinct cellular and therapeutic effects of obatoclax in rituximab-sensitive and -resistant lymphomas., PMID:21492126
Noxa mediates p18INK4c cell-cycle control of homeostasis in B cells and plasma cell precursors., PMID:21163929
Electroacupuncture protected pyramidal cells in hippocampal CA1 region of vascular dementia rats by inhibiting the expression of p53 and Noxa., PMID:20950325
Role of CAAT/enhancer binding protein homologous protein in panobinostat-mediated potentiation of bortezomib-induced lethal endoplasmic reticulum stress in mantle cell lymphoma cells., PMID:20647473
The role of glucocorticoid receptor phosphorylation in Mcl-1 and NOXA gene expression., PMID:20156337
A humanised anti-IGF-1R monoclonal antibody (AVE1642) enhances Bortezomib-induced apoptosis in myeloma cells lacking CD45., PMID:19165200
Immunohistochemical detection of BH3-only proteins in ameloblastic tumors., PMID:18826384
Noxa upregulation is associated with apoptosis of chronic lymphocytic leukemia cells induced by hyperforin but not flavopiridol., PMID:18784742
Histone deacetylase inhibitor FK228 enhances adenovirus-mediated p53 family gene therapy in cancer models., PMID:18413792
Interaction of Helicobacter pylori with gastric epithelial cells is mediated by the p53 protein family., PMID:18343378
Frequent loss of expression of the pro-apoptotic protein Bim in renal cell carcinoma: evidence for contribution to apoptosis resistance., PMID:17486061
A new p38 MAP kinase-regulated transcriptional coactivator that stimulates p53-dependent apoptosis., PMID:17380123
Interferons alpha and gamma induce p53-dependent and p53-independent apoptosis, respectively., PMID:15580300
Induction of PIG3 and NOXA through acetylation of p53 at 320 and 373 lysine residues as a mechanism for apoptotic cell death by histone deacetylase inhibitors., PMID:14695212
For research use only. Not for human or drug use.
