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Anti-PKD2 Antibody (R3S80)

Catalog #:   RHG58801 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: IHC, WB
Accession: Q13563
Overview

Catalog No.

RHG58801

Species reactivity

Human, Mouse

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

IHC: 1:500-1:1000, WB: 1:500-1:1000

Target

Autosomal dominant polycystic kidney disease type II protein, TRPP2, PC2, Polycystwin, Transient receptor potential cation channel subfamily P member 2, Polycystin-2, PKD2, Polycystic kidney disease 2 protein, R48321

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q13563

Applications

IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3S80

Data Image
  • Immunohistochemical
    IHC-P analysis of kidney tissue by PKD2 antibody (RHG58801). IHC-P was performed using sections of the formalin-fixed paraffin-embedded kidney tissue;Result: Cells of tubules are positively stained at the cytoplasm.
  • Western blot
    Lane 1: 15 µg of HEK-293 lysate; Lane 2: 15 µg of MCF-7 lysate; Lane 3: 15 µg of HeLa lysate;Lane 4: 15 µg of SH-SY5Y lysate; Lane 5: 15 µg of mouse kidney lysate; Result: RHG58801 can detect PKD2 by Western blotting;
References

The Diagnosis of Lupus Nephritis in A Patient with Autosomal Dominant Polycystic Kidney Disease: A Rare Case Report., PMID:40424494

A case of autosomal dominant polycystic kidney disease with systemic lupus erythematosus developing after SARS-CoV-2 vaccination., PMID:40392435

Paraneoplastic systemic sclerosis: A distinct entity or a mere association - A case report., PMID:40256100

Anti-Phospholipase A2 Receptor Antibody Testing to the Rescue., PMID:40060073

The Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) oncogene is upregulated in cystic epithelial cells revealing a potential new target for polycystic kidney disease., PMID:39666736

Monocyte/macrophage pyroptosis and C5b-9-induced cyst enlargement in Pkd1-/- mice., PMID:39528237

Causal relationships between three plasma proteins and non-alcoholic fatty liver disease, mediated by Epstein-Barr virus EA-D antibody levels: a mendelian randomization study., PMID:39463412

Renal Pelvic Cancer with Multiple Lung Metastases in a Patient with Polycystic Kidney Disease, Initially Diagnosed as Non-small Cell Lung Cancer: An Autopsy Case Report., PMID:39462594

Plasma exchange-sensitive syncytial glomerulopathy in a kidney transplant patient., PMID:39162815

Repeated human leukocyte antigens eplets, importance of typing the partner., PMID:38729449

Protein kinase D drives the secretion of invasion mediators in triple-negative breast cancer cell lines., PMID:38323010

Use of a donor kidney with known autosomal dominant polycystic kidney disease in a highly sensitised paediatric recipient., PMID:38231231

The Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) oncogene is upregulated in pre-cystic epithelial cells revealing a new target for polycystic kidney disease., PMID:38106222

Blood group-specific apheresis in combination with daratumumab as a rescue therapy of acute antibody-mediated rejection in a case of ABO- and human leukocyte antigen-incompatible kidney transplantation., PMID:38022864

In vivo Polycystin-1 interactome using a novel Pkd1 knock-in mouse model., PMID:37540694

Immune checkpoint activity regulates polycystic kidney disease progression., PMID:37345660

Pathophysiologic Implications and Therapeutic Approach of Klotho in Chronic Kidney Disease: A Systematic Review., PMID:37207706

Mechanism of cystogenesis by Cd79a-driven, conditional mTOR activation in developing mouse nephrons., PMID:36627370

Glucocorticoid in Combination with a TNF-α Inhibitor: Treatment of Deep Vein Thrombosis in a Patient with Behçet's Disease., PMID:36384897

Polycystin-2 (TRPP2) regulates primary cilium length in LLC-PK1 renal epithelial cells., PMID:36267587

Romosozumab successfully regulated progressive osteoporosis in a patient with autosomal dominant polycystic kidney disease undergoing hemodialysis., PMID:35980440

Outcomes of Kidney Transplantation in Patients with Autosomal Dominant Polycystic Kidney Disease: Our Experience Based on 35-Years Follow-Up., PMID:35626329

Antiphospholipid Syndrome in a Patient With Autosomal Dominant Polycystic Kidney Disease: The Surface of the Moon., PMID:35547412

Pkd1 Mutation Has No Apparent Effects on Peroxisome Structure or Lipid Metabolism., PMID:35372986

SGLT2 inhibitors in non-diabetic kidney disease., PMID:35077036

B Cell Receptor Signaling and Protein Kinase D2 Support Regulatory B Cell Function in Pancreatic Cancer., PMID:35046933

Allogeneic Kidney Transplantation After COVID-19: A Case Report., PMID:34753590

Early-Isolated V Lesion in Kidney Allograft: Acute Rejection or Ischemic Injury? A Case Report of Primary Nonfunction and Graft Loss., PMID:34465423

TWEAK Signaling Pathway Blockade Slows Cyst Growth and Disease Progression in Autosomal Dominant Polycystic Kidney Disease., PMID:34155062

Transient receptor potential polycystin-2 (TRPP2) regulates motility and intracellular calcium of porcine sperm., PMID:34042198

B cell and monocyte phenotyping: A quick asset to investigate the immune status in patients with IgA nephropathy., PMID:33740017

Significance of kidney biopsy in autosomal dominant tubulointerstitial kidney disease-UMOD: is kidney biopsy truly nonspecific?, PMID:33397327

Semi-Mechanistic Pharmacokinetic Model to Guide the Dose Selection of Nimotuzumab in Patients with Autosomal Dominant Polycystic Kidney Disease., PMID:33256255

Quetiapine-induced thrombotic microangiopathy in a patient on maintenance dialysis., PMID:32981026

PKD2/polycystin-2 induces autophagy by forming a complex with BECN1., PMID:32543276

Use of Checkpoint Inhibitors in a Kidney Transplant Recipient with Metastatic Cancer., PMID:32205320

Metalloproteinase PAPP-A regulation of IGF-1 contributes to polycystic kidney disease pathogenesis., PMID:31990681

Polycystin-1 Regulates Actomyosin Contraction and the Cellular Response to Extracellular Stiffness., PMID:31719603

Bilateral Nephrectomy for Adult Polycystic Kidney Disease Does Not Affect the Graft Function of Transplant Patients and Does Not Result in Sensitisation., PMID:31309115

[18F-FDG positron emission tomography in non-oncological renal pathology: Current indications and perspectives]., PMID:30982747

Fibroblast Primary Cilia Are Required for Cardiac Fibrosis., PMID:30818997

Safe Nanocomposite-Mediated Efficient Delivery of MicroRNA Plasmids for Autosomal Dominant Polycystic Kidney Disease (ADPKD) Therapy., PMID:30672150

Pharmacokinetic Evaluation of Nimotuzumab in Patients With Autosomal Dominant Polycystic Kidney Disease., PMID:30633365

[Nephrology : what's new in 2018 ?]., PMID:30629374

Emerging targeted strategies for the treatment of autosomal dominant polycystic kidney disease., PMID:30581563

The deubiquitinating enzyme Usp14 controls ciliogenesis and Hedgehog signaling., PMID:30388222

Case report: de novo ANCA-associated vasculitis after kidney transplantation treated with rituximab and plasma exchange., PMID:30340563

Biallelic Expression of Mucin-1 in Autosomal Dominant Tubulointerstitial Kidney Disease: Implications for Nongenetic Disease Recognition., PMID:30049680

A constitutive BCL2 down-regulation aggravates the phenotype of PKD1-mutant-induced polycystic kidney disease., PMID:28973148

Aberrant Smad3 phosphoisoforms in cyst-lining epithelial cells in the cpk mouse, a model of autosomal recessive polycystic kidney disease., PMID:28877884

Datasheet

Document Download

Anti-PKD2 Antibody (R3S80).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-PKD2 Antibody (R3S80) [RHG58801]
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