Catalog No.
RHG58202
Species reactivity
Human, Mouse, Rat
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IHC: 1:200-1:1000, WB: 1:500-1:2000
Target
Histone deacetylase 1, HDAC1, RPD3L1, HD1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q13547
Applications
ELISA, FCM, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3S70
Targeting mesenchymal monocyte-derived macrophages to enhance the sensitivity of glioblastoma to temozolomide by inhibiting TNF/CELSR2/p65/Kla-HDAC1/EPAS1 axis., PMID:40373963
Genetically encoding ε-N-methacryllysine into proteins in live cells., PMID:40097432
HDAC1-3 inhibition triggers NEDD4-mediated CCR2 downregulation and attenuates immunosuppression in myeloid-derived suppressor cells., PMID:39891718
Lactylation of HDAC1 Confers Resistance to Ferroptosis in Colorectal Cancer., PMID:39888307
Liver oval cells in response to HDAC1 inhibitor trichostatin A: immunohistochemical characterization using OV-6 hepatic expression., PMID:39809587
DNAJB1-PKAc Kinase Is Expressed in Young Patients with Pediatric Liver Cancers and Enhances Carcinogenic Pathways., PMID:39796711
[The effect of c-Myc on regulating the immune-related ligands in Y subtype small cell lung cancer through histone deacetylase 1]., PMID:39622733
Pharmacological activation of STAT1-GSDME pyroptotic circuitry reinforces epigenetic immunotherapy for hepatocellular carcinoma., PMID:39486886
Dissecting the Distinct Tumor Microenvironments of HRD and HRP Ovarian Cancer: Implications for Targeted Therapies to Overcome PARPi Resistance in HRD Tumors and Refractoriness in HRP Tumors., PMID:39136172
LNMAC Promotes Cervical Squamous Cell Carcinoma Lymphatic Metastasis via Epigenetic Regulation of FGF2-Induced Lymphangiogenesis., PMID:39119899
ESCCPred: a machine learning model for diagnostic prediction of early esophageal squamous cell carcinoma using autoantibody profiles., PMID:38956246
Calotropis procera: A double edged sword against glioblastoma, inhibiting glioblastoma cell line growth by targeting histone deacetylases (HDAC) and angiogenesis., PMID:38304784
HDAC1/2 control mesothelium/ovarian cancer adhesive interactions impacting on Talin-1-α5β1-integrin-mediated actin cytoskeleton and extracellular matrix protein remodeling., PMID:38254102
Expression of acetylated histones H3 and H4 and histone deacetylase enzymes HDAC1, HDAC2 and HDAC6 in simple mammary carcinomas of female dogs., PMID:38028583
Design and Synthesis of Triazole-Containing HDAC Inhibitors That Induce Antitumor Effects and Immune Response., PMID:36934335
A CRISPR/Cas9-mediated screen identifies determinants of early plasma cell differentiation., PMID:36685499
A Novel HDAC1-Selective Inhibitor Attenuates Autoimmune Arthritis by Inhibiting Inflammatory Cytokine Production., PMID:36047206
Expression of Protein Acetylation Regulators During Peripheral Nerve Development, Injury, and Regeneration., PMID:35663264
Exploring the mechanism of Qinbaiqingfei-concentrate pills in the treatment of Mycoplasma pneumoniae pneumonia from the perspective of intestinal microbiota and mucosal immunity., PMID:35460847
Perivascular Fibrosis Is Mediated by a KLF10-IL-9 Signaling Axis in CD4+ T Cells., PMID:35440172
Hepatic RACK1 deficiency protects against fulminant hepatitis through myeloid-derived suppressor cells., PMID:35265209
The methyltransferase METTL3 negatively regulates nonalcoholic steatohepatitis (NASH) progression., PMID:34893641
N6-Methyladenosine-Related RNA Signature Predicting the Prognosis of Ovarian Cancer., PMID:34137363
FACT subunit SUPT16H associates with BRD4 and contributes to silencing of antiviral interferon signaling., PMID:33907746
Combined genomic and proteomic approaches reveal DNA binding sites and interaction partners of TBX2 in the developing lung., PMID:33731112
Frequent amplification of HDAC genes and efficacy of HDAC inhibitor chidamide and PD-1 blockade combination in soft tissue sarcoma., PMID:33637599
Histone deacetylase (Rpd3) regulates Drosophila early brain development via regulation of Tailless., PMID:32873153
KLF5 inhibits STAT3 activity and tumor metastasis in prostate cancer by suppressing IGF1 transcription cooperatively with HDAC1., PMID:32546700
iNOS/NO is required for IRF1 activation in response to liver ischemia-reperfusion in mice., PMID:32517688
The regulation and function of CD20: an "enigma" of B-cell biology and targeted therapy., PMID:32482755
Histone deacetylase 1 (HDAC1): A key player of T cell-mediated arthritis., PMID:31883829
Molecular profiling of radical prostatectomy tissue from patients with no sign of progression identifies ERG as the strongest independent predictor of recurrence., PMID:31741711
Histone deacetylase 1 suppresses Krüppel homolog 1 gene expression and influences juvenile hormone action in Tribolium castaneum., PMID:31439816
Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L-dose dependency in HDAC1-deficient thymic lymphoma., PMID:31304633
Axotomy-Induced Changes of the Protein Profile in the Crayfish Ventral Cord Ganglia., PMID:31066008
Opposite regulation of Wnt/β-catenin and Shh signaling pathways by Rack1 controls mammalian cerebellar development., PMID:30765517
The Drosophila fussel gene is required for bitter gustatory neuron differentiation acting within an Rpd3 dependent chromatin modifying complex., PMID:30730884
[Primary skin lymphomas: Current therapy]., PMID:30709635
Integrated RNA-seq and ChIP-seq analysis reveals a feed-forward loop regulating H3K9ac and key labor drivers in human placenta., PMID:30642670
Improved early development of porcine cloned embryos by treatment with quisinostat, a potent histone deacetylase inhibitor., PMID:30587665
Upregulation of Znf179 acetylation by SAHA protects cells against oxidative stress., PMID:30121389
Mass spectrometry and DigiWest technology emphasize protein acetylation profile from Quisinostat-treated HuT78 CTCL cell line., PMID:30012418
Histone deacetylase inhibitor-based chromatin precipitation for identification of targeted genomic loci., PMID:29682593
Chronic sun exposure is associated with distinct histone acetylation changes in human skin., PMID:29150847
HDAC inhibitors enhance the immunotherapy response of melanoma cells., PMID:29137331
A systems medicine approach for finding target proteins affecting treatment outcomes in patients with non-Hodgkin lymphoma., PMID:28892521
Subcellular Localization of Maspin Correlates with Histone Deacetylase 1 Expression in Human Breast Cancer., PMID:28870936
Simultaneous Measurement of HDAC1 and HDAC6 Activity in HeLa Cells Using UHPLC-MS., PMID:28829415
The Co-Expression Pattern of p63 and HDAC1: A Potential Way to Disclose Stem Cells in Interfollicular Epidermis., PMID:28672879
Identification of zinc finger transcription factor EGR2 as a novel acetylated protein., PMID:28576496
For research use only. Not for human or drug use.
