Catalog No.
RHG55603
Species reactivity
Human
Host species
Mouse
Isotype
IgG2b
Clonality
Monoclonal
Tested applications
IP: 1:100-1:200
Target
TNFR2-TRAF-signaling complex protein 2, API1, hIAP2, BIRC2, C-IAP1, Inhibitor of apoptosis protein 2, hIAP-2, MIHB, RING finger protein 48, RNF48, Cellular inhibitor of apoptosis 1, RING-type E3 ubiquitin transferase BIRC2, Baculoviral IAP repeat-containing protein 2, IAP homolog B
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q13490
Applications
IP
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3S57
Selective disruption of Traf1/cIAP2 interaction attenuates inflammatory responses and rheumatoid arthritis., PMID:39913998
Deciphering pancreatic neuroendocrine tumors: Unveiling through circulating small extracellular vesicles., PMID:38596136
HIF-1α Mediates Immunosuppression and Chemoresistance in Colorectal Cancer by Inhibiting CXCL9, -10 and -11., PMID:38484558
Cleaved caspase-3 is present in the majority of glial cells in the intact rat spinal cord during postnatal life., PMID:37938347
Kaempferol sensitizes tumor necrosis factor-related apoptosis-inducing ligand-resistance chronic myelogenous leukemia cells to apoptosis., PMID:34820749
BET Inhibition Enhances TNF-Mediated Antitumor Immunity., PMID:34782346
BIRC2 Expression Impairs Anti-Cancer Immunity and Immunotherapy Efficacy., PMID:32846130
Next-generation hypomethylating agent SGI-110 primes acute myeloid leukemia cells to IAP antagonist by activating extrinsic and intrinsic apoptosis pathways., PMID:31831875
Dual Antagonist of cIAP/XIAP ASTX660 Sensitizes HPV- and HPV+ Head and Neck Cancers to TNFα, TRAIL, and Radiation Therapy., PMID:31266830
Zoledronic acid overcomes chemoresistance by sensitizing cancer stem cells to apoptosis., PMID:29300112
Targeting Non-proteolytic Protein Ubiquitination for the Treatment of Diffuse Large B Cell Lymphoma., PMID:27070702
Proteome profiling of cadmium-induced apoptosis by antibody array analyses in human bronchial epithelial cells., PMID:26716417
c-IAP ubiquitin protein ligase activity is required for 4-1BB signaling and CD8(+) memory T-cell survival., PMID:26096449
Natural Killer cell-dependent and non-dependent anti-viral activity of 2-Cys Peroxiredoxin against HIV., PMID:24244928
Smac mimetic compound LCL161 sensitizes esophageal carcinoma cells to radiotherapy by inhibiting the expression of inhibitor of apoptosis protein., PMID:24170321
Benzazepinones and benzoxazepinones as antagonists of inhibitor of apoptosis proteins (IAPs) selective for the second baculovirus IAP repeat (BIR2) domain., PMID:24083782
RIP1 protein-dependent assembly of a cytosolic cell death complex is required for inhibitor of apoptosis (IAP) inhibitor-mediated sensitization to lexatumumab-induced apoptosis., PMID:22927431
Deletion of cIAP1 and cIAP2 in murine B lymphocytes constitutively activates cell survival pathways and inactivates the germinal center response., PMID:21300983
CD30-induced up-regulation of the inhibitor of apoptosis genes cIAP1 and cIAP2 in anaplastic large cell lymphoma cells., PMID:15050749
Inhibition of nuclear translocation of transcription factor nuclear factor-kappa B induces FAS- as well as tumour necrosis factor-alpha-mediated apoptosis through downregulation of a conserved family of inhibitor of apoptosis 1., PMID:12603340
CD40 engagement enhances eosinophil survival through induction of cellular inhibitor of apoptosis protein 2 expression: Possible involvement in allergic inflammation., PMID:12209092
For research use only. Not for human or drug use.
