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Anti-ATM Antibody (R3S31)

Catalog #:   RHG48103 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2b
Applications: ELISA, FCM, IF, IHC
Accession: Q13315
Overview

Catalog No.

RHG48103

Species reactivity

Human, Mouse, Rat, Monkey

Host species

Mouse

Isotype

IgG2b

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000, IHC: 1:200-1:1000

Target

A-T mutated, Ataxia telangiectasia mutated, Serine-protein kinase ATM, ATM

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q13315

Applications

ELISA, FCM, IF, IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3S31

Data Image
  • Flow Cytometry
    Flow cytometric analysis of Hela cells using ATM mouse mAb (green) and negative control (red).
  • Flow Cytometry
    Flow cytometric analysis of COS-7 cells using ATM mouse mAb (green) and negative control (red).
  • Immunofluorescence
    Immunofluorescence analysis of Hela cells using ATM mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
  • Immunofluorescence
    Immunofluorescence analysis of NIH/3T3 cells using ATM mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human kidney tissues using ATM mouse mAb with DAB staining.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human kidney tissues using ATM mouse mAb with DAB staining.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human gastric cancer tissues using ATM mouse mAb with DAB staining.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded Mouse spleen tissues using ATM mouse mAb with DAB staining.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded Rat myocardium tissues using ATM mouse mAb with DAB staining.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded Rabbit spleen tissues using ATM mouse mAb with DAB staining.
References

Comparison of the Mutational Profile between BCL2- and BCL6-Rearrangement Positive Follicular Lymphoma., PMID:40482882

Focal High-Grade Areas with a Tumor-in-Tumor Pattern: Another Feature of Pediatric DICER1-Associated Thyroid Carcinoma?, PMID:40448797

Lutetium-177-PSMA-617 or cabazitaxel in metastatic prostate cancer: circulating tumor DNA analysis of the randomized phase 2 TheraP trial., PMID:40425844

Nonradiolabeled Radioresistant DNA Synthesis and S-Phase Checkpoint Analysis., PMID:40418471

The role of tungsten in modulating DNA double-strand break repair and class switch recombination., PMID:40360058

Clinical characteristics and outcome of double-AQP4/MOG-seronegative and not MS-associated monophasic and relapsing demyelinating transverse myelitis: A monocenter study., PMID:40288332

Ataxia Telangiectasia with Giant Suprasellar Arachnoid Cyst - A Case Report and a Brief Review., PMID:40231281

Deciphering the Cross-Reactivity of Tropomyosin across Three Molluscan Species: Insights into the Role of Conserved T-Cell and B-Cell Epitopes., PMID:40183940

Glofitamab in refractory or relapsed diffuse large B cell lymphoma after failing CAR-T cell therapy: a phase 2 LYSA study., PMID:40181090

Autoantibodies Against Factor B and Factor H Without Pathogenic Effects in a Patient with Immune Complex-Mediated Membranoproliferative Glomerulonephritis., PMID:40149624

Acute transverse myelitis following SARS-CoV-2 infection during treatment for ulcerative colitis with anti-TNFα therapy., PMID:40121774

The influence of homologous recombination repair on temozolomide chemosensitivity in gliomas., PMID:40120126

Longitudinally Extensive Transverse Myelitis (LETM) and Meningoencephalitis Following Acute Epstein-barr Virus Infection in an Immunocompetent Male: Case Report and Review Literature., PMID:40108929

Safety, tolerability and immunogenicity of a condensed, multi-dose prime regimen of PfSPZ Vaccine for the prevention of Plasmodium falciparum malaria infection., PMID:40098097

Elevated serum CD40 as a potential biomarker for the differential diagnosis of acute thyrotoxic myopathy., PMID:40069315

Homologous recombination repair status in metastatic prostate cancer by next-generation sequencing and functional immunofluorescence., PMID:39914385

Association of Specific Gene Mutations with Immunoglobulin Heavy-Chain Variable Region and Chromosomal Alterations in Chronic Lymphocytic Leukemia Patients in India., PMID:39873992

ATM Expression and Activation in Ataxia Telangiectasia Patients with and without Class Switch Recombination Defects., PMID:39853455

From phenotypic to molecular diagnosis: Insights from a clinical immunology service focused on inborn errors of immunity in Colombia., PMID:39836844

A targetable OSGIN1 - AMPK - SLC2A3 axis controls the vulnerability of ovarian cancer to ferroptosis., PMID:39809873

Mumps Myelitis-A Rare Cause of Myelitis., PMID:39773550

A Rare Case of a Malignant Proliferating Trichilemmal Tumor: A Molecular Study Harboring Potential Therapeutic Significance and a Review of Literature., PMID:39727620

Mutational Landscape of Bone Marrow CD19 and CD138 Cells in Waldenström Macroglobulinemia (WM) and IgM Monoclonal Gammopathy of Undetermined Significance (IgM MGUS)., PMID:39711167

Severe Transverse Myelitis Following Ankle Surgery Potentially Unmasking Late-Onset Systemic Lupus Erythematosus., PMID:39703303

The Impact of Resident Adipose Tissue Macrophages on Adipocyte Homeostasis and Dedifferentiation., PMID:39684730

Synthetic GPCRs for programmable sensing and control of cell behaviour., PMID:39633047

The Impact of Genetic Mutations on the Efficacy of Immunotherapies in Lung Cancer., PMID:39596025

Concurrent Guillain-Barre/acute transverse myelitis overlap syndrome after COVID-19 infection in a patient with ITP: A case report., PMID:39533593

Association between sore throat and early immune responses against COVID-19 before and after the emergence of the Omicron variant., PMID:39507451

Cancer Trends in Inborn Errors of Immunity: A Systematic Review and Meta-Analysis., PMID:39466473

The presence of oligoclonal bands predicts conversion to multiple sclerosis in isolated myelitis., PMID:39433553

Targeting RSV-neutralizing B cell receptors with anti-idiotypic antibodies., PMID:39383036

Abnormal brain regional activity in acute thyrotoxic myopathy assessed by resting-state functional MRI., PMID:39314056

Prediction of radiotherapy toxicity: 20 years of COPERNIC radiosensitivity diagnosis procedure., PMID:39307605

Tumor-agnostic cancer therapy using antibodies targeting oncofetal chondroitin sulfate., PMID:39215044

Saudi Initiative of Bronchiolitis Diagnosis, Management, and Prevention 2024 updated consensus on the prevention of respiratory syncytial virus., PMID:39144535

Immunity against conserved epitopes dominates after two consecutive exposures to SARS-CoV-2 Omicron BA.1., PMID:39097927

When Chromatin Decondensation Affects Nuclear γH2AX Foci Pattern and Kinetics and Biases the Assessment of DNA Double-Strand Breaks by Immunofluorescence., PMID:38927105

A gH/gL-encoding replicon vaccine elicits neutralizing antibodies that protect humanized mice against EBV challenge., PMID:38926438

Astrocytic stress response is induced by exposure to astrocyte-binding antibodies expressed by plasmablasts from pediatric patients with acute transverse myelitis., PMID:38915059

Unveiling Spatial Immune Cell Profile in Kidney Allograft Rejections Using 36-plex Immunofluorescence Imaging., PMID:38913785

Twenty-five years with HER2 targeted therapy., PMID:38911570

Clinical features and lymphocyte immunophenotyping analysis in primary immunodeficiency patients with non-transplant lymphoproliferative disorders., PMID:38838929

Analysis of early response to chemotherapy for non-Hodgkin's lymphoma by quantitative contrast-enhanced ultrasound: A prospective case-control crossectional study., PMID:38796885

Vaccination with nanoparticles displaying gH/gL from Epstein-Barr virus elicits limited cross-protection against rhesus lymphocryptovirus., PMID:38781964

Prognostic impact of genetic abnormalities in 536 first-line chronic lymphocytic leukaemia patients without 17p deletion treated with chemoimmunotherapy in two prospective trials: Focus on IGHV-mutated subgroups (a FILO study)., PMID:38654616

Evidence for persistent UV-induced DNA damage and altered DNA damage response in xeroderma pigmentosa patient corneas., PMID:38641197

Comparative analysis of tropomyosin allergenicity in three different species of molluscs: insights into the role of amino acid composition in IgE epitopes., PMID:38639426

Immunohistochemical findings and clinicopathological features of breast cancers with pathogenic germline mutations in Non-BRCA genes., PMID:38608781

Genomic determinants of response and resistance to inotuzumab ozogamicin in B-cell ALL., PMID:38551807

Datasheet

Document Download

Anti-ATM Antibody (R3S31).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-ATM Antibody (R3S31) [RHG48103]
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