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Anti-LpPLA2/PLA2G7/PAF-AH Antibody (R3S06)

Catalog #:   RHG39702 Specific References (36) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: ELISA, IF, IHC
Accession: Q13093
Overview

Catalog No.

RHG39702

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, IF: 1:200-1:1000, IHC: 1:200-1:1000

Target

Platelet-activating factor acetylhydrolase, PAFAH, PAF 2-acylhydrolase, PAF acetylhydrolase, 2-acetyl-1-alkylglycerophosphocholine esterase, 1-alkyl-2-acetylglycerophosphocholine esterase, LDL-PLA(2), LDL-associated phospholipase A2, PLA2G7, Group-VIIA phospholipase A2, gVIIA-PLA2

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q13093

Applications

ELISA, IF, IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3S06

Data Image
  • Immunofluorescence
    Immunofluorescence analysis of Hela cells using PLA2G7 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using PLA2G7 mouse mAb with DAB staining.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using PLA2G7 mouse mAb with DAB staining.
References

Black palladium nanoparticle-based lateral flow immunoassay for cardiovascular disease diagnosis., PMID:40365198

Propolis Reduces Inflammation and Dyslipidemia Caused by High-Cholesterol Diet in Mice by Lowering ADAM10/17 Activities., PMID:38931216

Novel Electrochemiluminescent Immunosensor Using Dual Amplified Signals from a CoFe Prussian Blue Analogue and Au Nanoparticle for the Detection of Lp-PLA2., PMID:37432366

Limited Proteolysis-Mass Spectrometry Reveals Aging-Associated Changes in Cerebrospinal Fluid Protein Abundances and Structures., PMID:36741774

A retrospective study of immunoglobulin E as a biomarker for the diagnosis of acute ischemic stroke with carotid atherosclerotic plaques., PMID:36317119

Establishment and clinical application of time-resolved immunofluorescence assay of lipoprotein-associated phospholipase A2., PMID:35351395

Lipid Receptor G2A-Mediated Signal Pathway Plays a Critical Role in Inflammatory Response by Promoting Classical Macrophage Activation., PMID:33941654

Au-coated Fe3O4 core-shell nanohybrids with photothermal activity for point-of-care immunoassay for lipoprotein-associated phospholipase A2 on a digital near-infrared thermometer., PMID:33048173

The selective lipoprotein-associated phospholipase A2 inhibitor darapladib triggers irreversible actions on glioma cell apoptosis and mitochondrial dysfunction., PMID:32668280

[Changes of serum lipoprotein-related phospholipase A2 in patients with white matter lesion based on KIM classification and its correlation with carotid atherosclerotic plaque]., PMID:32311875

ApoCIII-Lp(a) complexes in conjunction with Lp(a)-OxPL predict rapid progression of aortic stenosis., PMID:32054669

Pharmacokinetics and exploratory efficacy biomarkers of bococizumab, an anti-PCSK9 monoclonal antibody, in hypercholesterolemic Japanese subjects
., PMID:31549625

Genetic contributors and soluble mediators in prediction of autoimmune comorbidity., PMID:31444033

[Development and application of monoclonal antibodies anti-human lipoprotein-associated phospholipase A2]., PMID:30912356

Effects of Cervical Rotatory Manipulation (CRM) on Carotid Atherosclerosis Plaque in Vulnerability: A Histological and Immunohistochemical Study Using Animal Model., PMID:30863777

Novel Antiatherosclerotic Therapies., PMID:30816799

Chemiluminescence immunoassay for sensing lipoprotein-associated phospholipase A2 in cardiovascular risk evaluation., PMID:30414434

Photoelectrochemical immunoassay of lipoprotein-associated phospholipase A2 via plasmon-enhanced energy transfer between gold nanoparticles and CdS QDs/g-C3N4., PMID:30283999

Measurement of Lipoprotein-Associated Phospholipase A2 by Use of 3 Different Methods: Exploration of Discordance between ELISA and Activity Assays., PMID:29321128

Biochemical differences in the mass and activity tests of lipoprotein-associated phospholipase A2 explain the discordance in results between the two assay methods., PMID:28899631

Retinal pathology is associated with increased blood-retina barrier permeability in a diabetic and hypercholesterolaemic pig model: Beneficial effects of the LpPLA2 inhibitor Darapladib., PMID:28301218

Bioactive lysophospholipids generated by hepatic lipase degradation of lipoproteins lead to complement activation via the classical pathway., PMID:25205869

Association between lipoprotein associated phospholipase A2 mass and subclinical coronary and carotid atherosclerosis in Retired National Football League players., PMID:25105582

Oxidatively modified phosphatidylserines on the surface of apoptotic cells are essential phagocytic 'eat-me' signals: cleavage and inhibition of phagocytosis by Lp-PLA2., PMID:24464221

[Influence of intensive hypolipidemic therapy on blood concentration of lipoprotein-associated phospholipase A2 in patients with ischemic heart disease]., PMID:24090379

Influence of obesity and cardiometabolic makers on lipoprotein-associated phospholipase A2 (Lp-PLA2) activity in adolescents: the healthy young cross-sectional study., PMID:23413990

The effect of lipoprotein-associated phospholipase A2 deficiency on pulmonary allergic responses in Aspergillus fumigatus sensitized mice., PMID:23140447

Genetic and environmental regulation of inflammatory CVD biomarkers Lp-PLA2 and IgM anti-PC., PMID:21616491

Lipoprotein phospholipase A2 in patients with isolated coronary artery ectasia., PMID:21207044

Naturally occurring human plasminogen, like genetically related apolipoprotein(a), contains oxidized phosphatidylcholine adducts., PMID:20346413

The influence of pravastatin and atorvastatin on markers of oxidative stress in hypercholesterolemic humans., PMID:18436117

Patients with early rheumatoid arthritis exhibit elevated autoantibody titers against mildly oxidized low-density lipoprotein and exhibit decreased activity of the lipoprotein-associated phospholipase A2., PMID:17326817

Short- and long-term elevation of autoantibody titers against oxidized LDL in patients with acute coronary syndromes. Role of the lipoprotein-associated phospholipase A2 and the effect of atorvastatin treatment., PMID:17140582

Lipoprotein-associated phospholipase A2 protein expression in the natural progression of human coronary atherosclerosis., PMID:16960105

Autoantibody titers against OxLDL are correlated with Achilles tendon thickness in patients with familial hypercholesterolemia., PMID:16888320

Lipoprotein-associated phospholipase A(2), platelet-activating factor acetylhydrolase: a potential new risk factor for coronary artery disease., PMID:10856534

Datasheet
$ 220
Product specifications
50 μg 220 100 μg 350

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For research use only. Not for human or drug use.

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Anti-LpPLA2/PLA2G7/PAF-AH Antibody (R3S06) [RHG39702]
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