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Anti-AHNAK Antibody (R3R77)

Catalog #:   RHG20801 Specific References (27) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: ELISA, FCM, IF
Accession: Q09666
Overview

Catalog No.

RHG20801

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000

Target

Neuroblast differentiation-associated protein AHNAK, PM227, AHNAK, Desmoyokin

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q09666

Applications

ELISA, FCM, IF

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3R77

Data Image
  • Flow Cytometry
    Flow cytometric analysis of Hela cells using AHNAK mouse mAb (green) and negative control (red).
  • Flow Cytometry
    Flow cytometric analysis of HepG2 cells using AHNAK mouse mAb (green) and negative control (red).
  • Immunofluorescence
    Immunofluorescence analysis of Hela cells using AHNAK mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
References

Single-cell transcriptomic analysis reveals distinct plasma cell populations in chronic thromboembolic pulmonary hypertension., PMID:39965671

The Bioactive Peptide SL-13R Expands Human Umbilical Cord Blood Hematopoietic Stem and Progenitor Cells In Vitro., PMID:33915948

Engineered TCR-T Cell Immunotherapy in Anticancer Precision Medicine: Pros and Cons., PMID:33859650

Genomic Mapping Identifies Mutations in RYR2 and AHNAK as Associated with Favorable Outcome in Basal-Like Breast Tumors Expressing PD1/PD-L1., PMID:32796628

Ahnak-knockout mice show susceptibility to Bartonella henselae infection because of CD4+ T cell inactivation and decreased cytokine secretion., PMID:30940323

CINP is a novel cofactor of KLF5 required for its role in the promotion of cell proliferation, survival and tumor growth., PMID:30289973

Protective Function of Ahnak1 in Vascular Healing after Wire Injury., PMID:28468000

SUSD2 expression in high-grade serous ovarian cancer correlates with increased patient survival and defective mesothelial clearance., PMID:27775699

Huntingtin is associated with cytomatrix proteins at the presynaptic terminal., PMID:25461618

AHNAK is highly expressed and plays a key role in cell migration and invasion in mesothelioma., PMID:24253341

Function of Ahnak protein in aortic smooth muscle cell migration through Rac activation., PMID:23042471

Identification of a novel type of CA19-9 carrier in human bile and sera of cancer patients: an implication of the involvement in nonsecretory exocytosis., PMID:20954701

AHNAK1 and AHNAK2 are costameric proteins: AHNAK1 affects transverse skeletal muscle fiber stiffness., PMID:20833135

Presynaptic calcium channels and α3-integrins are complexed with synaptic cleft laminins, cytoskeletal elements and active zone components., PMID:20731762

The regulated exocytosis of enlargeosomes is mediated by a SNARE machinery that includes VAMP4., PMID:18713833

Spinal cord injury-induced up-regulation of AHNAK, expressed in cells delineating cystic cavities, and associated with neoangiogenesis., PMID:16930430

Diagnostic markers of ovarian cancer by high-throughput antigen cloning and detection on arrays., PMID:16424057

Highly purified lipoteichoic acid from gram-positive bacteria induces in vitro blood-brain barrier disruption through glia activation: role of pro-inflammatory cytokines and nitric oxide., PMID:16343789

The carboxyl-terminal ahnak domain induces actin bundling and stabilizes muscle contraction., PMID:15001564

Identification of AHNAK as a novel autoantigen in systemic lupus erythematosus., PMID:11866458

Multiple antibodies to titin immunoreact with AHNAK and localize to the mitotic spindle machinery., PMID:11746675

Signaling from beta-adrenoceptor to L-type calcium channel: identification of a novel cardiac protein kinase A target possessing similarities to AHNAK., PMID:10593863

Detection of antigens by immunofluorescence on ultrathin cryosections of skin., PMID:9815287

Desmoyokin/AHNAK protein localizes to the non-desmosomal keratinocyte cell surface of human epidermis., PMID:7769263

Regulation of translocation of the desmoyokin/AHNAK protein to the plasma membrane in keratinocytes by protein kinase C., PMID:7698224

Desmoyokin, a 680 kDa keratinocyte plasma membrane-associated protein, is homologous to the protein encoded by human gene AHNAK., PMID:8408266

The human gene AHNAK encodes a large phosphoprotein located primarily in the nucleus., PMID:8381120

Datasheet

Document Download

Anti-AHNAK Antibody (R3R77).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-AHNAK Antibody (R3R77) [RHG20801]
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