Catalog No.
RHG04606
Species reactivity
Human, Rat
Host species
Mouse
Isotype
IgG2b
Clonality
Monoclonal
Tested applications
WB: 1:500-1:1000
Target
Glutamate decarboxylase 2, GAD65, 65 kDa glutamic acid decarboxylase, GAD-65, GAD2, Glutamate decarboxylase 65 kDa isoform
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q05329
Applications
WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.5% BSA, 0.05% Sodium Azide and 50% Glycerol.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3R12
Transverse myelitis as a rare paraneoplastic manifestation of a pancreatic tail adenocarcinoma: A case report., PMID:40419916
Longitudinal EEG Characteristics of Anti-GAD65 Antibody Related Autoimmune Epilepsy., PMID:40368330
Clinical Features and Outcomes of Glutamic Acid Decarboxylase-65 Antibody-Associated Pure Cerebellar Ataxia and Stiff Person Syndrome Spectrum Disorders: A Single-Center Cohort Study., PMID:40342250
Structure and dynamics of GAD65 in complex with an autoimmune polyendocrine syndrome type 2-associated autoantibody., PMID:40055307
Upper motor neuron-predominant motor neuron disease: a novel immunotherapy-responsive association of GAD65 autoimmunity., PMID:39998694
Islet autoantibodies in Thai individuals diagnosed with type 1 diabetes before 30 years of age: a large multicentre nationwide study., PMID:39971754
The IVIG treatment response in autoimmune polyendocrine syndromes type 2 with anti-GAD65 antibody-associated stiff person syndrome: a case report and literature review., PMID:39840065
Anti-GAD65 musicogenic epilepsy: Bilateral and independent mesial temporal seizures revealed by foramen ovale electrodes., PMID:39835722
Glutamic Acid Decarboxylase 65 Antibody-associated Epilepsy and Diplopia: Two Case Reports with Literature Review., PMID:39658688
PAX6 is a useful marker for pancreatic origin of neuroendocrine neoplasms: A tissue microarray study evaluating more than 19,000 tumors from 150 different tumor types., PMID:39571690
Autoimmune encephalitis with coexisting antibodies to GABABR, GAD65, SOX1 and Ma2., PMID:39538282
CSF and blood signatures support classification of limbic encephalitis subtypes., PMID:39401553
LNP-mRNA vaccine prevents type 1 diabetes in non-obese diabetes mice., PMID:39278354
Progressive Encephalomyelitis With Rigidity and Myoclonus With Glycine Receptor and GAD65 Antibodies: Case Report and Potential Mechanisms., PMID:39213470
Spectrum of neurological manifestations, existence of diabetes mellitus, and 5-year mortality and cancer association outcomes in a cohort of Omani patients with positive anti- GAD autoimmunity., PMID:39167450
IT-DEX and B cell depletion in a child with anti-GAD 65 autoimmune encephalitis presenting as NORSE: A case report., PMID:39128431
Outcomes of surgical resection and vagus nerve stimulation in patients with medically refractory epilepsy and glutamic acid decarboxylase 65 antibody positivity., PMID:39110151
Machine learning characterization of a rare neurologic disease via electronic health records: a proof-of-principle study on stiff person syndrome., PMID:39097681
Management of autoimmune temporal lobe epilepsy with GAD65 antibody: four case reports., PMID:39093166
Editors' Note: Recurrent Rhombencephalitis Associated With Anti-GAD65 Antibody., PMID:39083754
Reader Response: Recurrent Rhombencephalitis Associated With Anti-GAD65 Antibody., PMID:39083716
Reader Response: Recurrent Rhombencephalitis Associated With Anti-GAD65 Antibody., PMID:39083702
Immunotherapy in a case of low titre GAD65 antibody-associated spectrum neurological disorders., PMID:38871638
Antibody-positive autoimmune encephalitis and paraneoplastic neurological syndrome: A Swedish case series., PMID:38702897
GAD2 Is a Highly Specific Marker for Neuroendocrine Neoplasms of the Pancreas., PMID:38271200
"Hot Cross Bun" Sign in a Patient with Glutamic Acid Decarboxylase 65-KDa Isoform Associated Cerebellar Ataxia: Case Report and Review of the Literature., PMID:37948023
Early Neuroaxonal Damage in Neurologic Disorders Associated With GAD65 Antibodies., PMID:37914416
Relationship Between the Response to Antibody Therapy and Symptoms of Depression and Anxiety Disorders in Patients with Severe Asthma., PMID:37096014
Identification of TPBG-Expressing Amacrine Cells in DAT-tdTomato Mouse., PMID:35551574
Similarities between bacterial GAD and human GAD65: Implications in gut mediated autoimmune type 1 diabetes., PMID:35196314
Unusual presentation of stiff-person syndrome in a patient with type 1 diabetes mellitus., PMID:35131796
Volumetric and shape analysis of the hippocampus in temporal lobe epilepsy with GAD65 antibodies compared with non-immune epilepsy., PMID:33986308
Formation of pancreatic β-cells from precursor cells contributes to the reversal of established type 1 diabetes., PMID:33866285
The profile of autoimmunity in Type 1 diabetes patients., PMID:33727507
Gonadotropin Stimulation Has Only a Limited Effect on the Concentration of Follicular Fluid Signalling Proteins: An Antibody Array Analysis., PMID:33575317
Neurofilament light chain levels reflect outcome in a patient with glutamic acid decarboxylase 65 antibody-positive autoimmune encephalitis under immune checkpoint inhibitor therapy., PMID:33556229
Seizures in autoimmune encephalitis-A systematic review and quantitative synthesis., PMID:33475161
Antibodies Contributing to Focal Epilepsy Signs and Symptoms Score., PMID:33427313
GAD65-Related Immune Epilepsy: Are we Looking Yet?, PMID:33420634
Rats deficient in the GAD65 isoform exhibit epilepsy and premature lethality., PMID:33236473
α6GABAA Receptor Positive Modulators Alleviate Migraine-like Grimaces in Mice via Compensating GABAergic Deficits in Trigeminal Ganglia., PMID:33111258
Confirmation and Identification of Biomarkers Implicating Environmental Triggers in the Pathogenesis of Type 1 Diabetes., PMID:33042112
AntiGAD65 antibodies encephalitis with lateralized periodic discharges: A case report., PMID:32801107
Epilepsy in patients with insulin-dependent diabetes and relation to glutamic acid decarboxylase 65., PMID:32683400
Clinical characteristics and outcomes of autoimmune encephalitis patients associated with anti-glutamate decarboxylase antibody 65., PMID:32682224
Drebrin expression patterns in patients with refractory temporal lobe epilepsy and hippocampal sclerosis., PMID:32662890
Clinical features and immunotherapy outcomes of anti-glutamic acid decarboxylase 65 antibody-associated neurological disorders., PMID:32563127
Low rate of glutamic acid decarboxylase 65 (GAD-65) antibodies in chronic epilepsy., PMID:32512284
Neurological Syndromes Associated with Anti-GAD Antibodies., PMID:32456344
Why is the presence of autoantibodies against GAD associated with a relatively slow progression to clinical diabetes?, PMID:32451571
For research use only. Not for human or drug use.
