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Anti-GAD2/GAD65 Antibody (R3R11)

Catalog #:   RHG04605 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: ELISA, FCM
Accession: Q05329
Overview

Catalog No.

RHG04605

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400

Target

Glutamate decarboxylase 2, GAD65, 65 kDa glutamic acid decarboxylase, GAD-65, GAD2, Glutamate decarboxylase 65 kDa isoform

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q05329

Applications

ELISA, FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3R11

Data Image
  • Flow Cytometry
    Flow cytometric analysis of Hela cells using GAD2 mouse mAb (green) and negative control (red).
References

Transverse myelitis as a rare paraneoplastic manifestation of a pancreatic tail adenocarcinoma: A case report., PMID:40419916

Longitudinal EEG Characteristics of Anti-GAD65 Antibody Related Autoimmune Epilepsy., PMID:40368330

Clinical Features and Outcomes of Glutamic Acid Decarboxylase-65 Antibody-Associated Pure Cerebellar Ataxia and Stiff Person Syndrome Spectrum Disorders: A Single-Center Cohort Study., PMID:40342250

Structure and dynamics of GAD65 in complex with an autoimmune polyendocrine syndrome type 2-associated autoantibody., PMID:40055307

Upper motor neuron-predominant motor neuron disease: a novel immunotherapy-responsive association of GAD65 autoimmunity., PMID:39998694

Islet autoantibodies in Thai individuals diagnosed with type 1 diabetes before 30 years of age: a large multicentre nationwide study., PMID:39971754

The IVIG treatment response in autoimmune polyendocrine syndromes type 2 with anti-GAD65 antibody-associated stiff person syndrome: a case report and literature review., PMID:39840065

Anti-GAD65 musicogenic epilepsy: Bilateral and independent mesial temporal seizures revealed by foramen ovale electrodes., PMID:39835722

Glutamic Acid Decarboxylase 65 Antibody-associated Epilepsy and Diplopia: Two Case Reports with Literature Review., PMID:39658688

PAX6 is a useful marker for pancreatic origin of neuroendocrine neoplasms: A tissue microarray study evaluating more than 19,000 tumors from 150 different tumor types., PMID:39571690

Autoimmune encephalitis with coexisting antibodies to GABABR, GAD65, SOX1 and Ma2., PMID:39538282

CSF and blood signatures support classification of limbic encephalitis subtypes., PMID:39401553

LNP-mRNA vaccine prevents type 1 diabetes in non-obese diabetes mice., PMID:39278354

Progressive Encephalomyelitis With Rigidity and Myoclonus With Glycine Receptor and GAD65 Antibodies: Case Report and Potential Mechanisms., PMID:39213470

Spectrum of neurological manifestations, existence of diabetes mellitus, and 5-year mortality and cancer association outcomes in a cohort of Omani patients with positive anti- GAD autoimmunity., PMID:39167450

IT-DEX and B cell depletion in a child with anti-GAD 65 autoimmune encephalitis presenting as NORSE: A case report., PMID:39128431

Outcomes of surgical resection and vagus nerve stimulation in patients with medically refractory epilepsy and glutamic acid decarboxylase 65 antibody positivity., PMID:39110151

Machine learning characterization of a rare neurologic disease via electronic health records: a proof-of-principle study on stiff person syndrome., PMID:39097681

Management of autoimmune temporal lobe epilepsy with GAD65 antibody: four case reports., PMID:39093166

Editors' Note: Recurrent Rhombencephalitis Associated With Anti-GAD65 Antibody., PMID:39083754

Reader Response: Recurrent Rhombencephalitis Associated With Anti-GAD65 Antibody., PMID:39083716

Reader Response: Recurrent Rhombencephalitis Associated With Anti-GAD65 Antibody., PMID:39083702

Immunotherapy in a case of low titre GAD65 antibody-associated spectrum neurological disorders., PMID:38871638

Antibody-positive autoimmune encephalitis and paraneoplastic neurological syndrome: A Swedish case series., PMID:38702897

GAD2 Is a Highly Specific Marker for Neuroendocrine Neoplasms of the Pancreas., PMID:38271200

"Hot Cross Bun" Sign in a Patient with Glutamic Acid Decarboxylase 65-KDa Isoform Associated Cerebellar Ataxia: Case Report and Review of the Literature., PMID:37948023

Early Neuroaxonal Damage in Neurologic Disorders Associated With GAD65 Antibodies., PMID:37914416

Relationship Between the Response to Antibody Therapy and Symptoms of Depression and Anxiety Disorders in Patients with Severe Asthma., PMID:37096014

Identification of TPBG-Expressing Amacrine Cells in DAT-tdTomato Mouse., PMID:35551574

Similarities between bacterial GAD and human GAD65: Implications in gut mediated autoimmune type 1 diabetes., PMID:35196314

Unusual presentation of stiff-person syndrome in a patient with type 1 diabetes mellitus., PMID:35131796

Volumetric and shape analysis of the hippocampus in temporal lobe epilepsy with GAD65 antibodies compared with non-immune epilepsy., PMID:33986308

Formation of pancreatic β-cells from precursor cells contributes to the reversal of established type 1 diabetes., PMID:33866285

The profile of autoimmunity in Type 1 diabetes patients., PMID:33727507

Gonadotropin Stimulation Has Only a Limited Effect on the Concentration of Follicular Fluid Signalling Proteins: An Antibody Array Analysis., PMID:33575317

Neurofilament light chain levels reflect outcome in a patient with glutamic acid decarboxylase 65 antibody-positive autoimmune encephalitis under immune checkpoint inhibitor therapy., PMID:33556229

Seizures in autoimmune encephalitis-A systematic review and quantitative synthesis., PMID:33475161

Antibodies Contributing to Focal Epilepsy Signs and Symptoms Score., PMID:33427313

GAD65-Related Immune Epilepsy: Are we Looking Yet?, PMID:33420634

Rats deficient in the GAD65 isoform exhibit epilepsy and premature lethality., PMID:33236473

α6GABAA Receptor Positive Modulators Alleviate Migraine-like Grimaces in Mice via Compensating GABAergic Deficits in Trigeminal Ganglia., PMID:33111258

Confirmation and Identification of Biomarkers Implicating Environmental Triggers in the Pathogenesis of Type 1 Diabetes., PMID:33042112

AntiGAD65 antibodies encephalitis with lateralized periodic discharges: A case report., PMID:32801107

Epilepsy in patients with insulin-dependent diabetes and relation to glutamic acid decarboxylase 65., PMID:32683400

Clinical characteristics and outcomes of autoimmune encephalitis patients associated with anti-glutamate decarboxylase antibody 65., PMID:32682224

Drebrin expression patterns in patients with refractory temporal lobe epilepsy and hippocampal sclerosis., PMID:32662890

Clinical features and immunotherapy outcomes of anti-glutamic acid decarboxylase 65 antibody-associated neurological disorders., PMID:32563127

Low rate of glutamic acid decarboxylase 65 (GAD-65) antibodies in chronic epilepsy., PMID:32512284

Neurological Syndromes Associated with Anti-GAD Antibodies., PMID:32456344

Why is the presence of autoantibodies against GAD associated with a relatively slow progression to clinical diabetes?, PMID:32451571

Datasheet
$ 220
Product specifications
50 μg 220 100 μg 350

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Distributor list

For research use only. Not for human or drug use.

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Anti-GAD2/GAD65 Antibody (R3R11) [RHG04605]
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