Catalog No.
RHG01006
Species reactivity
Human, Mouse, Rat
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
IHC: 1:50-1:100, IP: 1:20, WB: 1:500-1:1000
Target
Nuclear factor NF-kappa-B p65 subunit, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, RELA, Transcription factor p65, NFKB3
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q04206
Applications
IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.5% BSA, 0.05% Sodium Azide and 50% Glycerol.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3Q90
TAP1 promotes immune escape by activating JNK/STAT1/PD-L1 signaling in EBV-associated gastric cancer., PMID:40500531
Small Nuclear Ribonucleoprotein Autoantibody Associated With Blood-Nerve Barrier Breakdown in Guillain-Barré Syndrome., PMID:40388674
Buzhong Yiqi decoction improves inflammation and oxidative damage in autoimmune thyroiditis by inhibiting apoptosis via the SIRT1-Mediated Nrf2/NF-κB axis., PMID:40360040
Discovery of novel adjuvants: Identification of saponins from Hylomecon japonica (Thunb.) Prantl & Kündig and insights into their in vitro and in vivo activities., PMID:40318505
PD-1 suppression enhances HIV reactivation and T-cell immunity via MAPK/NF-κB signaling., PMID:40186291
Crude Polygalae Radix after boiling with licorice decoction alleviates intestinal mucosal barrier injury of rats by regulating TLR4/NF-κB signaling pathway., PMID:40120702
LuQi formula ameliorates pressure overload-induced heart failure by regulating macrophages and regulatory T cells., PMID:40118747
Citrullination of NF-κB p65 by PAD2 as a Novel Therapeutic Target for Modulating Macrophage Polarization in Acute Lung Injury., PMID:40087815
Metformin Ameliorates Ulcerative Colitis Through Inhibiting NLRP3 Inflammasome Activation., PMID:39931167
DNMT3A transcriptionally downregulated by KLF5 alleviates LPS-induced inflammatory response and promotes osteogenic differentiation in hPDLSCs., PMID:39476105
A Novel Trichinella spiralis Galectin Strengthens the Macrophage ADCC Killing of Larvae via Driving M1 Polarization., PMID:39456703
Chromatin remodelling drives immune cell-fibroblast communication in heart failure., PMID:39443808
Evaluation of Anti-Inflammatory and Immunosuppressant Potential of Isotelekin in Lipopolysaccharide (LPS) Stimulated Macrophage (RAW 264.7) and Sheep Red Blood Cells (SRBC) Sensitized Murine Models., PMID:39410831
Low to moderate ethanol exposure reduces astrocyte-induced neuroinflammatory signaling and cognitive decline in presymptomatic APP/PS1 mice., PMID:39402264
DNp73 enhances tumor progression and immune evasion in multiple myeloma by targeting the MYC and MYCN pathways., PMID:39380995
IL-8 promotes lens capsular residual cells migration by down-regulates expression of E-cadherin and ZO-1 via the CXCR1/2-NF-κB-RhoA signal pathway., PMID:39244903
Based on SIRT1/NF-κB/NLRP3 Signal Pathway to Explore the Effect of Yiqi Huatan Huoxue Recipe on Inflammatory Injury in AIT Mice by Pyroptosis., PMID:39136510
Monocarboxylate transporter 4 facilitates Mycobacterium tuberculosis survival through NF-κB p65-mediated interleukin-10 production., PMID:39108720
The oncogenic kinase TOPK upregulates in psoriatic keratinocytes and contributes to psoriasis progression by regulating neutrophils infiltration., PMID:39090602
Effects of Aeromonas infection on the immune system, physical barriers and microflora structure in the intestine of juvenile grass carp (Ctenopharyngodon idella)., PMID:39059563
DLK1 regulates periodontal inflammation by inhibiting NF-κB p65 and JNK signaling pathways., PMID:38995322
Coexistence of systemic sclerosis and cryopyrin-associated periodic syndrome., PMID:38940218
Effect of IL-9 neutralising antibody on pyroptosis via SGK1/NF-κB/NLRP3/GSDMD in allergic rhinitis mice., PMID:38917753
Inhibition of nucleophosmin/B23 sensitizes ovarian cancer cells to immune check-point blockade via PD-L1 in ovarian cancer., PMID:38821736
Acupuncture at "Die E acupoint" alleviates inflammatory reaction via inhibiting TLR4/MyD88/NF-κB signaling in rats with allergic rhinitis., PMID:38764116
Protective effect of modified Huangqi Chifeng decoction on immunoglobulin A nephropathy through toll-like receptor 4/myeloid differentiation factor 88/nuclear factor-kappa B signaling pathway., PMID:38504538
B-cell receptor signaling activity identifies patients with mantle cell lymphoma at higher risk of progression., PMID:38503806
Three Artemisia pollens trigger the onset of allergic rhinitis via TLR4/MyD88 signaling pathway., PMID:38388914
Acupoint application therapy alleviates pain by regulating immune function through inhibiting TLR4/MyD88/NF-κB p65 signaling in a primary dysmenorrhea rat model., PMID:38239137
Exploration of the immuno-adjuvant effect and mechanism of Anemoside B4 through network pharmacology and experiment verification., PMID:38176273
DWN12088, A Prolyl-tRNA Synthetase Inhibitor, Alleviates Hepatic Injury in Nonalcoholic Steatohepatitis., PMID:38173372
Moderate ethanol exposure reduces astrocyte-induced neuroinflammatorysignaling and cognitive decline in presymptomatic APP/PS1 mice., PMID:38077051
Cold-inducible RNA-binding protein induces inflammatory responses via NF-κB signaling pathway in normal human bronchial epithelial cells infected with streptococcus pneumoniae., PMID:38064816
Trichinella spiralis cathepsin L induces macrophage M1 polarization via the NF-κB pathway and enhances the ADCC killing of newborn larvae., PMID:37993938
Nucleoporin downregulation modulates progenitor differentiation independent of nuclear pore numbers., PMID:37853046
DNA-dependent protein kinase catalytic subunit binds to the transactivation domain 1 of NF-κB p65., PMID:37674974
Shikonin prevents mice from heat stroke-induced death via suppressing a trigger IL-17A on the inflammatory and oxidative pathways., PMID:37643485
Anti-cerebral ischemic neuronal injury mechanism of Zhenlong Xingnao capsules: role of the Notch/NF-κB signaling pathway., PMID:37560215
Role of interleukin-36γ induced by ultraviolet radiation in chronic actinic dermatitis., PMID:37545106
[IL-33 up-regulates eIF3a expression by activating NF-κB signaling pathway to mediate the proliferation and differentiation of mouse pulmonary myofibroblasts and aggravate pulmonary fibrosis]., PMID:37515335
Formononetin Inhibits Mast Cell Degranulation to Ameliorate Compound 48/80-Induced Pseudoallergic Reactions., PMID:37446928
Glutamine metabolic microenvironment drives M2 macrophage polarization to mediate trastuzumab resistance in HER2-positive gastric cancer., PMID:37434399
Pathogenicity and innate immune responses induced by fowl adenovirus serotype 8b in specific pathogen-free chicken., PMID:37354616
Fenofibrate attenuates asthma features in an ovalbumin-induced mouse model via suppressing NF-κB binding activity., PMID:37295485
Rituximab exerts its anti-arthritic effects via inhibiting NF-κB/GM-CSF/iNOS signaling in B cells in a mouse model of collagen-induced arthritis., PMID:37274671
Impact of Toll-like Receptor 4 Expression on Inflammatory Responses Related to Premature Membrane Rupture Induced by Lipopolysaccharide., PMID:37272109
IL-17C neutralization protects the kidney against acute injury and chronic injury., PMID:37263138
Leocarpinolide B Attenuates Collagen Type II-Induced Arthritis by Inhibiting DNA Binding Activity of NF-κB., PMID:37241980
IL-23/IL-17 immune axis mediates the imiquimod-induced psoriatic inflammation by activating ACT1/TRAF6/TAK1/NF-κB pathway in macrophages and keratinocytes., PMID:37098777
Benzene induces spleen injury through the B cell receptor signaling pathway., PMID:37080132
For research use only. Not for human or drug use.
