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Anti-RELB Antibody (R3Q36)

Catalog #:   RHF86206 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a
Applications: ELISA, FCM, IF, IHC
Accession: Q01201
Overview

Catalog No.

RHF86206

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000, IHC: 1:200-1:1000

Target

RELB, Transcription factor RelB, I-Rel

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q01201

Applications

ELISA, FCM, IF, IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3Q36

Data Image
  • Flow Cytometry
    Flow cytometric analysis of MCF-7 cells using RELB mouse mAb (green) and negative control (red).
  • Immunofluorescence
    Immunofluorescence analysis of MCF-7 cells using RELB mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using RELB mouse mAb with DAB staining.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using RELB mouse mAb with DAB staining.
References

Intratumoral Fusobacterium nucleatum Recruits Tumor-Associated Neutrophils to Promote Gastric Cancer Progression and Immune Evasion., PMID:39992708

CD40 induces PIR-A+ macrophages to promote chronic allograft rejection., PMID:39954660

B cells expressing mutated IGHV1-69-encoded antigen receptors related to virus neutralization show lymphoma-like transcriptomes in patients with chronic HCV infection., PMID:39082968

IFI35 regulates non-canonical NF-κB signaling to maintain glioblastoma stem cells and recruit tumor-associated macrophages., PMID:38594444

Effect of glutamine on the systemic innate immune response in broiler chickens challenged with Salmonella pullorum., PMID:38102601

Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency., PMID:37938781

Vitamin D3 mitigates autoimmune inflammation caused by activation of myeloid dendritic cells in SLE., PMID:37702410

Functionalized Parylene Films for Enhancement of Antibody Production by Hybridoma Cells., PMID:37647153

BET inhibition targets ABC-DLBCL constitutive B-cell receptor signaling through PAX5., PMID:37184294

Tuning the expression of the bacterial relBE toxin-antitoxin system in Saccharomyces cerevisiae allows characterizing the subsequent growth inhibition., PMID:36722160

Sustained activation of non-canonical NF-κB signalling drives glycolytic reprogramming in doxorubicin-resistant DLBCL., PMID:36446947

Uncovering Novel Prognostic Factors of Sudden Sensorineural Hearing Loss by Whole-Genome Sequencing of Cell-Free DNA., PMID:36349665

Nfkb2 deficiency and its impact on plasma cells and immunoglobulin expression in murine small intestinal mucosa., PMID:35916405

Functional analysis of Escherichia coli K12 toxin-antitoxin systems as novel drug targets using a network biology approach., PMID:35853597

Identifying predictive signalling networks for Vedolizumab response in ulcerative colitis., PMID:35543875

An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity., PMID:35148840

Cyclic Helix B Peptide Prolongs Skin Allograft Survival via Inhibition of B Cell Immune Responses in a Murine Model., PMID:34054874

Noncanonical NF-κB Signaling Pathway in Liver Diseases., PMID:33604258

Quantitative assessment of NFκB transcription factor activity., PMID:33388338

Dectin-1 Facilitates IL-18 Production for the Generation of Protective Antibodies Against Candida albicans., PMID:32765468

Sox8 is essential for M cell maturation to accelerate IgA response at the early stage after weaning in mice., PMID:30877171

Integrated RNA-seq and ChIP-seq analysis reveals a feed-forward loop regulating H3K9ac and key labor drivers in human placenta., PMID:30642670

Immature lung TNFR2- conventional DC 2 subpopulation activates moDCs to promote cyclic di-GMP mucosal adjuvant responses in vivo., PMID:30327534

A systems medicine approach reveals disordered immune system and lipid metabolism in multiple sclerosis patients., PMID:29194580

RelB-Deficient Dendritic Cells Promote the Development of Spontaneous Allergic Airway Inflammation., PMID:28960101

Lymphotoxins Promote the Progression of Human Lymphatic Malformation by Enhancing Lymphatic Endothelial Cell Proliferation., PMID:28837798

Parthenolide reduces gene transcription of prosurvival mediators in U937 cells., PMID:28361855

Bacterial Genome Editing via a Designed Toxin-Antitoxin Cassette., PMID:28094982

Transcription factors of the alternative NF-κB pathway are required for germinal center B-cell development., PMID:27457956

Functional characterization of RelBE toxin-antitoxin system in probiotic Bifidobacterium longum JDM301., PMID:27451444

Rapid Curtailing of the Stringent Response by Toxin-Antitoxin Module-Encoded mRNases., PMID:27137501

Comprehensive phenotypic characterization of PTLD reveals potential reliance on EBV or NF-κB signalling instead of B-cell receptor signalling., PMID:26799990

The Mycobacterium tuberculosis relBE toxin:antitoxin genes are stress-responsive modules that regulate growth through translation inhibition., PMID:26502963

Classical and alternative NF-κB signaling cooperate in regulating adipocyte differentiation and function., PMID:26403432

The effects of RelB deficiency on lymphocyte development and function., PMID:26385063

The AhR and NF-κB/Rel Proteins Mediate the Inhibitory Effect of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin on the 3' Immunoglobulin Heavy Chain Regulatory Region., PMID:26377645

Potential Cross-Talk between Alternative and Classical NF-κB Pathways in Prostate Cancer Tissues as Measured by a Multi-Staining Immunofluorescence Co-Localization Assay., PMID:26186215

Methods to assess the activation of the alternative (noncanonical) NF-κB pathway by non-death TNF receptors., PMID:25736746

DBC1 is a suppressor of B cell activation by negatively regulating alternative NF-κB transcriptional activity., PMID:25362179

Imipramine exploits histone deacetylase 11 to increase the IL-12/IL-10 ratio in macrophages infected with antimony-resistant Leishmania donovani and clears organ parasites in experimental infection., PMID:25217162

Pathological activation of canonical nuclear-factor κB by synergy of tumor necrosis factor α and TNF-like weak inducer of apoptosis in mouse acute colitis., PMID:25022957

Transcription factors involved in prostate gland adaptation to androgen deprivation., PMID:24886974

Small-angle X-ray scattering- and nuclear magnetic resonance-derived conformational ensemble of the highly flexible antitoxin PaaA2., PMID:24768114

Geldanamycin-mediated inhibition of heat shock protein 90 partially activates dendritic cells, but interferes with their full maturation, accompanied by impaired upregulation of RelB., PMID:24524692

Nuclear Factor κB is Required for Tumor Growth Inhibition Mediated by Enavatuzumab (PDL192), a Humanized Monoclonal Antibody to TweakR., PMID:24409185

NF-κB2/p100 deficiency impairs immune responses to T-cell-independent type 2 antigens., PMID:24242887

Established thymic epithelial progenitor/stem cell-like cell lines differentiate into mature thymic epithelial cells and support T cell development., PMID:24086471

RelB, together with RelA, sustains cell survival and confers proteasome inhibitor sensitivity of chronic lymphocytic leukemia cells from bone marrow., PMID:24042463

[Distribution of genes of toxin-antitoxin systems of mazEF and relBE families in bifidobacteria from human intestinal microbiota]., PMID:23755531

The chemotherapeutic agent topotecan differentially modulates the phenotype and function of dendritic cells., PMID:23666509

Datasheet

Document Download

Anti-RELB Antibody (R3Q36).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-RELB Antibody (R3Q36) [RHF86206]
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