Please ensure Javascript is enabled for purposes of website accessibility
Home / Products / Antibody / Recombinant Antibody

Anti-E2F1/RBBP3 Antibody (R3Q30)

Catalog #:   RHF85302 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: ELISA, FCM, IHC, WB
Accession: Q01094
Overview

Catalog No.

RHF85302

Species reactivity

Human, Mouse

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, IHC: 1:200-1:1000, WB: 1:500-1:2000

Target

Retinoblastoma-binding protein 3, Retinoblastoma-associated protein 1, RBBP-3, Transcription factor E2F1, RBBP3, E2F1, E2F-1, RBAP-1, pRB-binding protein E2F-1, PBR3

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q01094

Applications

ELISA, FCM, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3Q30

Data Image
  • Flow Cytometry
    Flow cytometric analysis of HeLa cells using E2F1 mouse mAb (green) and negative control (red).
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human esophageal cancer tissues using E2F1 mouse mAb with DAB staining.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using E2F1 mouse mAb with DAB staining.
  • Western blot
    Western blot analysis using E2F1 mouse mAb against HeLa (1), SK-N-SH (2), and NIH3T3 (3) cell lysate.
References

Tirbanibulin decreases cell proliferation and downregulates protein expression of oncogenic pathways in human papillomavirus containing HeLa cells., PMID:38967656

Unveiling the Molecular Mechanism of Trastuzumab Resistance in SKBR3 and BT474 Cell Lines for HER2 Positive Breast Cancer., PMID:38534787

TP53/mTORC1-mediated bidirectional regulation of PD-L1 modulates immune evasion in hepatocellular carcinoma., PMID:38030304

EZH2 regulates pancreatic cancer cells through E2F1, GLI1, CDK3, and Mcm4., PMID:37198697

Artificial Intelligence Predicted Overall Survival and Classified Mature B-Cell Neoplasms Based on Immuno-Oncology and Immune Checkpoint Panels., PMID:36358737

Tumor Derived Extracellular Vesicles Drive T Cell Exhaustion in Tumor Microenvironment through Sphingosine Mediated Signaling and Impacting Immunotherapy Outcomes in Ovarian Cancer., PMID:35289120

Translational control of E2f1 regulates the Drosophila cell cycle., PMID:35074910

Relationship between IGF-1 and body weight in inflammatory bowel diseases: Cellular and molecular mechanisms involved., PMID:34601192

Anti-Proliferative Effects of E2F1 Suppression in Glioblastoma Cells., PMID:34482308

LMCD1 antisense RNA 1 is a newly identified long noncoding RNA., PMID:34232945

In search for biomarkers and potential drug targets for uterine serous endometrial cancer., PMID:33754208

Regulation of E2F1 activity via PKA-mediated phosphorylations., PMID:33110360

RPL21 siRNA Blocks Proliferation in Pancreatic Cancer Cells by Inhibiting DNA Replication and Inducing G1 Arrest and Apoptosis., PMID:33014855

Downregulation of SRPK2 promotes cell cycle arrest though E2F1 in non-small cell lung cancer., PMID:31833327

PCSK9 inhibition as a novel therapeutic target for alcoholic liver disease., PMID:31748600

Axotomy-Induced Changes of the Protein Profile in the Crayfish Ventral Cord Ganglia., PMID:31066008

NFATc1-E2F1-LMCD1-Mediated IL-33 Expression by Thrombin Is Required for Injury-Induced Neointima Formation., PMID:31043075

Human adipose tissue H3K4me3 histone mark in adipogenic, lipid metabolism and inflammatory genes is positively associated with BMI and HOMA-IR., PMID:30958852

Proteasome inhibition boosts autophagic degradation of ubiquitinated-AGR2 and enhances the antitumor efficiency of bevacizumab., PMID:30647455

Inhibition of microRNA-299-5p sensitizes glioblastoma cells to temozolomide via the MAPK/ERK signaling pathway., PMID:30061180

Cladribine in combination with entinostat synergistically elicits anti-proliferative/anti-survival effects on multiple myeloma cells., PMID:29969371

Decreased osteoprogenitor proliferation precedes attenuation of cancellous bone formation in ovariectomized rats treated with sclerostin antibody., PMID:29955626

Arsenic treatment increase Aurora-A overexpression through E2F1 activation in bladder cells., PMID:28420331

KLF6 Suppresses Metastasis of Clear Cell Renal Cell Carcinoma via Transcriptional Repression of E2F1., PMID:27780824

Profiling of Signaling Proteins in Penumbra After Focal Photothrombotic Infarct in the Rat Brain Cortex., PMID:27771897

CADM1 regulates the G1/S transition and represses tumorigenicity through the Rb-E2F pathway in hepatocellular carcinoma., PMID:27298105

Hepatitis B Virus X Protein Upregulates hELG1/ ATAD5 Expression through E2F1 in Hepatocellular Carcinoma., PMID:26722215

V-ATPase: a master effector of E2F1-mediated lysosomal trafficking, mTORC1 activation and autophagy., PMID:26356814

A novel placental like alkaline phosphatase promoter driven transcriptional silencing combined with single chain variable fragment antibody based virosomal delivery for neoplastic cell targeting [corrected]., PMID:26242403

Genome-wide analysis of the oxyntic proliferative isthmus zone reveals ASPM as a possible gastric stem/progenitor cell marker over-expressed in cancer., PMID:26178168

E2F8 as a Novel Therapeutic Target for Lung Cancer., PMID:26089541

Immunological data from cancer patients treated with Ad5/3-E2F-Δ24-GMCSF suggests utility for tumor immunotherapy., PMID:25714011

Exploring the genes associated with the response to intravenous immunoglobulin in patients with Kawasaki disease using DNA microarray analysis., PMID:25449331

E2F1 suppresses cardiac neovascularization by down-regulating VEGF and PlGF expression., PMID:25341896

E2F1 induces miR-224/452 expression to drive EMT through TXNIP downregulation., PMID:25341426

ERBB2 deficiency alters an E2F-1-dependent adaptive stress response and leads to cardiac dysfunction., PMID:25246633

Association of RHAMM with E2F1 promotes tumour cell extravasation by transcriptional up-regulation of fibronectin., PMID:25042645

Unraveling natalizumab effects on deregulated miR-17 expression in CD4+ T cells of patients with relapsing-remitting multiple sclerosis., PMID:24901013

Transcription of the Geminin gene is regulated by a negative-feedback loop., PMID:24554762

Distinct and site-specific phosphorylation of the retinoblastoma protein at serine 612 in differentiated cells., PMID:24466208

Loss of dE2F compromises mitochondrial function., PMID:24286825

MicroRNA-155 controls RB phosphorylation in normal and malignant B lymphocytes via the noncanonical TGF-β1/SMAD5 signaling module., PMID:24136167

The E2F1/DNMT1 axis is associated with the development of AR negative castration resistant prostate cancer., PMID:24038143

E2F1 promotes angiogenesis through the VEGF-C/VEGFR-3 axis in a feedback loop for cooperative induction of PDGF-B., PMID:24014887

The monoclonal antibody CH12 augments 5-fluorouracil-induced growth suppression of hepatocellular carcinoma xenografts expressing epidermal growth factor receptor variant III., PMID:24007863

FOXO transcription factors control E2F1 transcriptional specificity and apoptotic function., PMID:23966291

Dynamic changes in the initial colonization of Actinomyces naeslundii and Streptococcus gordonii using a new animal model., PMID:23429078

Replication protein a links cell cycle progression and the onset of neurogenesis in Drosophila optic lobe development., PMID:23407946

Antiproliferative activity of Alpinia officinarum extract in the human breast cancer cell line MCF-7., PMID:23404367

Transgenesis-mediated reproductive dysfunction and tumorigenesis: effects of immunological neutralization., PMID:23226476

Datasheet
$ 220
Product specifications
50 μg 220 100 μg 350

Contact Information

Order: order@antibodysystem.com

Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

Need help with your order?

Find out more about placing an order here

Anti-E2F1/RBBP3 Antibody (R3Q30) [RHF85302]
Terms of sale Website terms of use Cookie policy Privacy
Copyright © 2025 AntibodySystem SAS. All Rights Reserved.            All Products are for Research Use Only