Catalog No.
RHF78603
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IHC: 1:200-1:1000
Target
Mucin-5 subtype AC, tracheobronchial, Gastric mucin, Mucin-5AC, TBM, MUC-5AC, Tracheobronchial mucin, Major airway glycoprotein, MUC5AC, MUC5
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P98088
Applications
ELISA, FCM, IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3Q03
Dynamics of Bacteria-Mucus Interactions: Quantitative Assessment of MUC5AC and Helicobacter pylori Adhesion to the Gastric Tissue on the Model of Cavia porcellus., PMID:40498303
Intranasal Immunotherapy with Allergen-Loaded Extracellular Vesicles from Mast Cells Alleviates Allergic Asthma Inflammation in a Murine Model., PMID:40366524
Exploring the optimal timing of HanChuan Zupa Granule for asthma treatment using a comprehensive research approach of "Disease circadian rhythm-drug target prediction-drug efficacy validation"., PMID:40254112
Immunohistochemical insights into the pathogenesis of colonic sessile serrated lesions., PMID:40135194
TIM-1 attenuates airway mucus hypersecretion and inflammation induced by cigarette smoke via the PI3K/Akt signaling pathway., PMID:39871096
Vaccination of mice with Trichinella spiralis C-type lectin elicited the protective immunity and enhanced gut epithelial barrier function., PMID:39841790
[Protective effect of Streptococcus salivarius K12 against Mycoplasma pneumoniae infection in mice]., PMID:39725618
Targeting Human Pancreatic Cancer with a Fluorophore-Conjugated Mucin 4 (MUC4) Antibody: Initial Characterization in Orthotopic Cell Line Mouse Models., PMID:39458160
Detection of MUC1+/MUC2 and MUC5AC- Membrane-Associated Mucins in the Intraepithelial Surface Mucous Cells of the Developing Rabbit Esophagus., PMID:39396509
First-in-Human Total-Body PET/CT Imaging Using 89Zr-Labeled MUC5AC Antibody in a Patient with Pancreatic Adenocarcinoma., PMID:39237345
Mature MUC5AC Expression in Resected Pancreatic Ductal Adenocarcinoma Predicts Treatment Response and Outcomes., PMID:39201728
Variability in morphology and immunohistochemistry of Crohn's disease-associated small bowel neoplasms: implications of Claudin 18 and Cadherin 17 expression for tumor-targeted immunotherapies., PMID:39164422
Effects of Benzo[α]pyrene on Mucus Secretion and Tissue Remodeling in a Rat Model of Allergic Rhinitis., PMID:39148236
Non-invasive strategy: Developing a topical IL-4Rα-specific nanobody for the treatment of allergic airway diseases., PMID:39108557
Teleost Muc2 and Muc5ac: Key guardians of mucosal immunity in flounder (Paralichthys olivaceus)., PMID:39053833
Effect of chronic stress on gel-forming mucins in the small intestine of BALB/c mice., PMID:39044931
Increased Muc5AC and Decreased Ciliated Cells in Severe Asthma Partially Restored by Inhibition of IL-4Rα Receptor., PMID:38935626
GammaGateR: semi-automated marker gating for single-cell multiplexed imaging., PMID:38833684
Exacerbated lung inflammation in offspring with high maternal antibody levels following secondary RSV exposure., PMID:38745662
Gastroprotective effects of polysaccharides from purple sweet potato (Ipomoea batatas (L.) Lam) on an ethanol-induced gastric ulcer via regulating immunity and activating the PI3K/Akt/Rheb/mTOR pathway., PMID:38726829
Down-Regulation of INSR Restores Th17/Treg Immune Balance and Alleviates Airway Hyperviscosity in Asthmatic Mice via Inactivation of STAT3 Pathway., PMID:38409842
Ocular surface disease in moderate-to-severe atopic dermatitis patients and the effect of biological therapy., PMID:38332535
IL-17 receptor A functions to help maintain barrier integrity and limit activation of immunopathogenic response to H. pylori infection., PMID:38014948
Histopathological features of glandular atrophy of the lamina propria of the gastric mucosa during its occurrence and development., PMID:37968594
The protective immunity induced by Trichinella spiralis galectin against larval challenge and the potential of galactomannan as a novel adjuvant., PMID:37931574
Therapeutic potential of Lianhua Qingke in airway mucus hypersecretion of acute exacerbation of chronic obstructive pulmonary disease., PMID:37924136
Colloid Carcinoma Arising in an Intestinal-Type Intraductal Papillary Mucinous Neoplasm with High-Grade Dysplasia Appearing as Signet-Ring Cells of the Pancreas by Serial Pancreatic Juice Aspiration Cytology: A Case Report., PMID:37835866
Diminishing of Helicobacter pylori adhesion to Cavia porcellus gastric epithelial cells by BCG vaccine mycobacteria., PMID:37770504
Qufeng Xuanbi Formula inhibited benzo[a]pyrene-induced aggravated asthma airway mucus secretion by AhR/ROS/ERK pathway., PMID:37734473
TCN1 Expression Is Increased in Asthma., PMID:37586352
Effects of total alkaloids from Alstonia scholaris (L.) R. Br. on ovalbumin-induced asthma mice., PMID:37460031
Effects of 101BHG-D01, a novel M receptor antagonism, on allergic rhinitis in animal models and its mechanism., PMID:37422119
Genetic regulators of sputum mucin concentration and their associations with COPD phenotypes., PMID:37352370
Effect of Dupilumab on Type 2 Biomarkers in Chronic Rhinosinusitis With Nasal Polyps: SINUS-52 Study Results., PMID:37322842
Highly Selective Targeting of Pancreatic Cancer in the Liver with a Near-Infrared Anti-MUC5AC Probe in a PDOX Mouse Model: A Proof-of-Concept Study., PMID:37241027
Specific Targeting and Labeling of Colonic Polyps in CPC-APC Mice with Mucin 5AC Fluorescent Antibodies: A Model for Detection of Early Colon Cancer., PMID:37185743
Predictive Value of MUC5AC Signature in Pancreatic Ductal Adenocarcinoma: A Hypothesis Based on Preclinical Evidence., PMID:37175794
IL-1β promotes IL-17A production of ILC3s to aggravate neutrophilic airway inflammation in mice., PMID:36988516
Dupilumab-associated ocular surface disease in atopic dermatitis patients: Clinical characteristics, ophthalmic treatment response and conjunctival goblet cell analysis., PMID:36934403
Gleditsia sinensis Lam. aqueous extract attenuates nasal inflammation in allergic rhinitis by inhibiting MUC5AC production through suppression of the STAT3/STAT6 pathway., PMID:36921533
Exogenous Lipoxin A4 attenuates IL4-induced Mucin Expression in Human Airway Epithelial Cells., PMID:36860679
[Mucins expression in gastric cancer: connection of MUC status with clinical, morphological and prognostic characteristics of the tumor]., PMID:36785958
Effect of a MUC5AC Antibody (NPC-1C) Administered With Second-Line Gemcitabine and Nab-Paclitaxel on the Survival of Patients With Advanced Pancreatic Ductal Adenocarcinoma: A Randomized Clinical Trial., PMID:36602796
Different Molecular Forms of TFF3 in the Human Respiratory Tract: Heterodimerization with IgG Fc Binding Protein (FCGBP) and Proteolytic Cleavage in Bronchial Secretions., PMID:36499686
Antibody-Drug Conjugates Targeting Tumor-Specific Mucin Glycoepitopes., PMID:36472102
Clinicopathological and genetic analyses of pulmonary enteric adenocarcinoma., PMID:36456172
HDAC4 depletion ameliorates IL-13-triggered inflammatory response and mucus production in nasal epithelial cells via activation of SIRT1/NF-κB signaling., PMID:36301023
Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules., PMID:35776514
Mucin 5AC expression is common but unrelated to tumor progression in pancreatic adenocarcinoma., PMID:35764407
Iristectorigenin A exerts novel protective properties against airway inflammation and mucus hypersecretion in OVA-induced asthmatic mice: Iristectorigenin A ameliorates asthma phenotype., PMID:35752075
For research use only. Not for human or drug use.
