Catalog No.
RHF78503
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000
Target
DOC-2, Adaptor molecule disabled-2, Differentially-expressed protein 2, Disabled homolog 2, Differentially expressed in ovarian carcinoma 2, DOC2, DAB2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P98082
Applications
ELISA, FCM, IF
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3Q01
Translational two-pore PBPK model to characterize whole-body disposition of different-size endogenous and exogenous proteins., PMID:38691205
Role of Lipid Rafts on LRP8 Signaling Triggered by Anti-β2-GPI Antibodies in Endothelial Cells., PMID:38137358
Multiplex proteomics using proximity extension assay for the identification of protein biomarkers predictive of acute graft-vs.-host disease in allogeneic hematopoietic cell transplantation., PMID:36655501
Beta-Hydroxybutyric Acid Inhibits Renal Tubular Reabsorption via the AKT/DAB2/Megalin Signalling Pathway., PMID:36330072
Increased LCN2 (lipocalin 2) in the RPE decreases autophagy and activates inflammasome-ferroptosis processes in a mouse model of dry AMD., PMID:35473441
Massive digital gene expression analysis reveals different predictive profiles for immune checkpoint inhibitor therapy between adenocarcinoma and squamous cell carcinoma of advanced lung cancer., PMID:35135489
Protein Phosphatase 2A Activation Via ApoER2 in Trophoblasts Drives Preeclampsia in a Mouse Model of the Antiphospholipid Syndrome., PMID:34404233
A plasma-derived extracellular vesicle mRNA classifier for the detection of breast cancer., PMID:34268084
Integrin αIIbβ3 outside-in signaling activates human platelets through serine 24 phosphorylation of Disabled-2., PMID:33557943
Lysosome-Rich Enterocytes Mediate Protein Absorption in the Vertebrate Gut., PMID:31474562
Characterizing the B-Cell and Humoral Response in Tertiary Lymphoid Organs in Kidney Allografts., PMID:30880652
The antiphospholipid syndrome finally fathomed?, PMID:29748168
Antiphospholipid antibodies induce thrombosis by PP2A activation via apoER2-Dab2-SHC1 complex formation in endothelium., PMID:29500169
Functional links between Disabled-2 Ser723 phosphorylation and thrombin signaling in human platelets., PMID:28876503
Expression and Histopathological Significance of Disabled-2 in Aldosterone-Producing Adenoma., PMID:28514805
A Novel Monoclonal Antibody Against Human DAB2IP., PMID:26301928
A Versatile Monoclonal Antibody Specific Against Human DAB2IP., PMID:26301927
A genome-wide association study for clinical mastitis in first parity US Holstein cows using single-step approach and genomic matrix re-weighting procedure., PMID:25658712
Dsh homolog DVL3 mediates resistance to IGFIR inhibition by regulating IGF-RAS signaling., PMID:25168481
Downregulation of DAB2IP promotes mesenchymal-to-neuroepithelial transition and neuronal differentiation of human mesenchymal stem cells., PMID:24073285
Expression and clinical significance of the transforming growth factor-β signalling pathway in endometrial cancer., PMID:21771027
Effect of IVF and laser zona dissection on DNA methylation pattern of mouse zygotes., PMID:19823912
Focal adhesion disassembly requires clathrin-dependent endocytosis of integrins., PMID:19306879
Disabled-2 is a novel alphaIIb-integrin-binding protein that negatively regulates platelet-fibrinogen interactions and platelet aggregation., PMID:17074833
Autocrine signaling of platelet-derived growth factor regulates disabled-2 expression during megakaryocytic differentiation of K562 cells., PMID:16061224
Mutually dependent localization of megalin and Dab2 in the renal proximal tubule., PMID:15870384
Cloning and characterization of mouse disabled 2 interacting protein 2, a mouse orthologue of human NOSTRIN., PMID:15596140
Association of the transcriptional corepressor TIF1beta with heterochromatin protein 1 (HP1): an essential role for progression through differentiation., PMID:15342492
Lipoprotein receptors and a disabled family cytoplasmic adaptor protein regulate EGL-17/FGF export in C. elegans., PMID:14630941
Disabled-2 inactivation is an early step in ovarian tumorigenicity., PMID:10340382
For research use only. Not for human or drug use.
