Catalog No.
RHF53702
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400
Target
Ras-related protein Rap-1A, RAP1A, G-22K, KREV1, GTP-binding protein smg p21A, C21KG, Ras-related protein Krev-1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P62834
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3P24
Viral escape-inspired framework for structure-guided dual bait protein biosensor design., PMID:40233103
Genetics in neovascular age-related macular degeneration susceptibility and treatment response to anti-VEGF intravitreal injection: A case series study., PMID:38757252
Geranylgeranyl isoprenoids and hepatic Rap1a regulate basal and statin-induced expression of PCSK9., PMID:38309417
Theileria equi RAP-1a and RAP-1b proteins contain immunoreactive epitopes and are suitable candidates for vaccine and diagnostics development., PMID:35318949
Rap1 Is Essential for B-Cell Locomotion, Germinal Center Formation and Normal B-1a Cell Population., PMID:34140948
Large Extracellular Vesicle-Associated Rap1 Accumulates in Atherosclerotic Plaques, Correlates With Vascular Risks and Is Involved in Atherosclerosis., PMID:32539601
Unraveling the Prenylation-Cancer Paradox in Multiple Myeloma with Novel Geranylgeranyl Pyrophosphate Synthase (GGPPS) Inhibitors., PMID:30016091
Molecular and serological detection of bovine babesiosis in Indonesia., PMID:29110723
The Rap1-cofilin-1 pathway coordinates actin reorganization and MTOC polarization at the B cell immune synapse., PMID:28167682
RAP-1a is the main rhoptry-associated-protein-1 (RAP-1) recognized during infection with Babesia sp. BQ1 (Lintan) (B. motasi-like phylogenetic group), a pathogen of sheep in China., PMID:27890082
Expression of sheep pathogen Babesia sp. Xinjiang rhoptry-associated protein 1 and evaluation of its diagnostic potential by enzyme-linked immunosorbent assay., PMID:27748232
Expression analysis and biological characterization of Babesia sp. BQ1 (Lintan) (Babesia motasi-like) rhoptry-associated protein 1 and its potential use in serodiagnosis via ELISA., PMID:27245213
Rap1 GTPase Inhibits Tumor Necrosis Factor-α-Induced Choroidal Endothelial Migration via NADPH Oxidase- and NF-κB-Dependent Activation of Rac1., PMID:26476350
GABAB receptor promotes its own surface expression by recruiting a Rap1-dependent signaling cascade., PMID:25967549
The Ras-related protein, Rap1A, mediates thrombin-stimulated, integrin-dependent glioblastoma cell proliferation and tumor growth., PMID:24790104
Immunohistochemical assay for detection of K-ras protein expression in metastatic colorectal cancer., PMID:23499207
Radil controls neutrophil adhesion and motility through β2-integrin activation., PMID:23097489
Small GTPases Rap1 and RhoA regulate superoxide formation by Rac1 GTPases activation during the phagocytosis of IgG-opsonized zymosans in macrophages., PMID:22330068
Statins inhibit T-acute lymphoblastic leukemia cell adhesion and migration through Rap1b., PMID:21233409
Endothelin signaling via guanine exchange factor C3G in renal glomerular mesangial cells., PMID:20725139
Junctional adhesion molecule A interacts with Afadin and PDZ-GEF2 to activate Rap1A, regulate beta1 integrin levels, and enhance cell migration., PMID:19176753
Expression analysis of heat shock protein 20 and rhoptry-associated protein 1a in sexual stages and kinetes of Babesia bigemina., PMID:19120192
Rap1b regulates B cell development, homing, and T cell-dependent humoral immunity., PMID:18714009
Identification and biochemical characterization of Rap2C, a new member of the Rap family of small GTP-binding proteins., PMID:16213650
Babesia bigemina: sporozoite isolation from Boophilus microplus nymphs and initial immunomolecular characterization., PMID:15604497
On the role of electrostatic interactions in the design of protein-protein interfaces., PMID:12054776
v-Src transformation is mediated through farnesylated proteins., PMID:11469908
RhoB prenylation is driven by the three carboxyl-terminal amino acids of the protein: evidenced in vivo by an anti-farnesyl cysteine antibody., PMID:11027361
Selection of phage-displayed fab antibodies on the active conformation of ras yields a high affinity conformation-specific antibody preventing the binding of c-Raf kinase to Ras., PMID:10601649
RAP1A GTP/GDP cycles determine the intracellular location of the late endocytic compartments and contribute to myogenic differentiation., PMID:9882515
Expression and localization of RAP1 proteins during myogenic differentiation., PMID:8900487
Ultrastructural localization of the small GTP-binding protein Rap1 in human platelets and megakaryocytes., PMID:7803284
Association of Rap1a and Rap1b proteins with late endocytic/phagocytic compartments and Rap2a with the Golgi complex., PMID:7962206
Evidence for Rap1 in vascular smooth muscle cells. Regulation of their expression by platelet-derived growth factor BB., PMID:8143870
Mapping small GTP-binding proteins on high-resolution two-dimensional gels by a combination of GTP binding and labeling with in situ periodate-oxidized GTP., PMID:8026445
Correlated expression of the 97 kDa sarcoendoplasmic reticulum Ca(2+)-ATPase and Rap1B in platelets and various cell lines., PMID:8297341
Mutational analysis of the cAMP-dependent protein kinase-mediated phosphorylation site of Rap1b., PMID:8463283
Partial purification of a GTPase-activating protein for rap2b from bovine brain membranes., PMID:1472043
Regulation of the GTPase activity of the ras-related rap2 protein., PMID:1449497
Generation of specific antibodies against the rap1A, rap1B and rap2 small GTP-binding proteins. Analysis of rap and ras proteins in membranes from mammalian cells., PMID:1628649
Subcellular distribution of the Rap1A protein in human neutrophils: colocalization and cotranslocation with cytochrome b559., PMID:1312373
Rap1A is a substrate for cyclic AMP-dependent protein kinase in human neutrophils., PMID:1908879
Association of the Ras-antagonistic Rap1/Krev-1 proteins with the Golgi complex., PMID:1900364
RAP2B: a RAS-related GTP-binding protein from platelets., PMID:2118648
Rap1-B is phosphorylated by protein kinase A in intact human platelets., PMID:1696481
Tissue and subcellular distributions of the smg-21/rap1/Krev-1 proteins which are partly distinct from those of c-ras p21s., PMID:2111441
For research use only. Not for human or drug use.
