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Anti-ADAR/IFI4 Antibody (R3N41)

Catalog #:   RHF11403 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: ELISA, FCM, IF
Accession: P55265
Overview

Catalog No.

RHF11403

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000

Target

Double-stranded RNA-specific adenosine deaminase, G1P1, IFI-4, ADAR, K88DSRBP, DRADA, ADAR1, IFI4, Interferon-inducible protein 4, p136, 136 kDa double-stranded RNA-binding protein, DSRAD

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P55265

Applications

ELISA, FCM, IF

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3N41

Data Image
  • Flow Cytometry
    Flow cytometric analysis of Hela cells using ADAR mouse mAb (green) and negative control (red).
  • Flow Cytometry
    Flow cytometric analysis of Jurkat cells using ADAR mouse mAb (green) and negative control (red).
  • Immunofluorescence
    Immunofluorescence analysis of Hela cells using ADAR mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
References

3'UTR RNA editing driven by ADAR1 modulates MDM2 expression in breast cancer cells., PMID:40381037

ADARp110 promotes hepatocellular carcinoma progression via stabilization of CD24 mRNA., PMID:39808660

Predicting graft survival in paediatric kidney transplant recipients using machine learning., PMID:39150523

Quantification of AMPA receptor subunits and RNA editing-related proteins in the J20 mouse model of Alzheimer's disease by capillary western blotting., PMID:38299128

Immunologic and Protective Properties of Subunit- vs. Whole Toxoid-Derived Anti-Botulinum Equine Antitoxin., PMID:36146601

IFN-I inducible miR-3614-5p targets ADAR1 isoforms and fine tunes innate immune activation., PMID:35935998

Single-cell RNA Sequencing Analysis Reveals New Immune Disorder Complexities in Hypersplenism., PMID:35865544

Adenosine-Deaminase-Acting-on-RNA-1 Facilitates T-cell Migration toward Human Melanoma Cells., PMID:35731225

Not "If", but "When" and "How": Testing Antibody-Drug Conjugates in Patients with Non-muscle-invasive Bladder Cancer., PMID:34838351

Evaluation of a downstream process for the recovery and concentration of a Cell-Culture-Derived rVSV-Spike COVID-19 vaccine candidate., PMID:34756612

Host Immune Response Driving SARS-CoV-2 Evolution., PMID:32992592

Clinical and serological features of dermatomyositis and systemic lupus erythematosus patients with autoantibodies to ADAR1., PMID:32907776

Host immune response driving SARS-CoV-2 evolution., PMID:32839723

RNA editing contributes to epitranscriptome diversity in chronic lymphocytic leukemia., PMID:32728184

MS2-TRIBE Evaluates Both Protein-RNA Interactions and Nuclear Organization of Transcription by RNA Editing., PMID:32674054

RNA editing as a therapeutic approach for retinal gene therapy requiring long coding sequences., PMID:31991730

Infectious vaccine-derived rubella viruses emerge, persist, and evolve in cutaneous granulomas of children with primary immunodeficiencies., PMID:31658304

RNA editing in the forefront of epitranscriptomics and human health., PMID:31547885

AKT-dependent phosphorylation of the adenosine deaminases ADAR-1 and -2 inhibits deaminase activity., PMID:31095429

Comparative safety and effectiveness of tumor necrosis factor α antagonists and vedolizumab in elderly IBD patients: a multicentre study., PMID:30773667

Illuminating spatial A-to-I RNA editing signatures within the Drosophila brain., PMID:30659150

APOBEC and ADAR deaminases may cause many single nucleotide polymorphisms curated in the OMIM database., PMID:29957488

ADAR1-mediated regulation of melanoma invasion., PMID:29855470

Integrative Analysis of Immunological Data to Explore Chronic Immune T-Cell Activation in Successfully Treated HIV Patients., PMID:28046052

REPLY: Treatment with oxLDL antibody reduces cathepsin S expression in atherosclerosis via down-regulating ADAR1-mediated RNA editing., PMID:28003044

Treatment with oxLDL antibody reduces cathepsin S expression in atherosclerosis via down-regulating ADAR1-mediated RNA editing., PMID:27956316

Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation., PMID:27595325

TRIBE: Hijacking an RNA-Editing Enzyme to Identify Cell-Specific Targets of RNA-Binding Proteins., PMID:27040499

The Importance of Intestinal Eotaxin-1 in Inflammatory Bowel Disease: New Insights and Possible Therapeutic Implications., PMID:26874691

A Phase III Study of Balugrastim Versus Pegfilgrastim in Breast Cancer Patients Receiving Chemotherapy With Doxorubicin and Docetaxel., PMID:26668251

A novel immune resistance mechanism of melanoma cells controlled by the ADAR1 enzyme., PMID:26338962

Single nucleotide polymorphisms/haplotypes associated with multiple rubella-specific immune response outcomes post-MMR immunization in healthy children., PMID:26329766

Oral Administration of OKT3 MAb to Patients with NASH, Promotes Regulatory T-cell Induction, and Alleviates Insulin Resistance: Results of a Phase IIa Blinded Placebo-Controlled Trial., PMID:25876706

Stability of the parainfluenza virus 5 genome revealed by deep sequencing of strains isolated from different hosts and following passage in cell culture., PMID:24453358

Assessment of interferon-related biomarkers in Aicardi-Goutières syndrome associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, and ADAR: a case-control study., PMID:24183309

Oral administration of immunoglobulin G-enhanced colostrum alleviates insulin resistance and liver injury and is associated with alterations in natural killer T cells., PMID:22236001

Genetic polymorphisms in host antiviral genes: associations with humoral and cellular immunity to measles vaccine., PMID:21939710

Non-ST Elevation Myocardial Infraction after High Dose Intravenous Immunoglobulin Infusion., PMID:20182639

Cholestatic jaundice induced by atorvastatin: a possible association with antimitochondrial antibodies., PMID:19911499

Adalimumab-induced autoimmune hepatitis., PMID:19593165

A universal epitope-based influenza vaccine and its efficacy against H5N1., PMID:19356612

ADAR1 and ADAR2 expression and editing activity during forebrain development., PMID:19325227

Inversing the natural hydrogen bonding rule to selectively amplify GC-rich ADAR-edited RNAs., PMID:18515351

ICAM1 and VCAM1 polymorphisms, coronary artery calcium, and circulating levels of soluble ICAM-1: the multi-ethnic study of atherosclerosis (MESA)., PMID:18420209

A method to find tissue-specific novel sites of selective adenosine deamination., PMID:16257978

Identification of new targets of Drosophila pre-mRNA adenosine deaminase., PMID:15522950

Contribution of immunological memory to protective immunity conferred by a Bacillus anthracis protective antigen-based vaccine., PMID:15155654

Characterization and application of Raman labels for confocal Raman microspectroscopic detection of cellular proteins in single cells., PMID:14596828

Human combinatorial Fab library yielding specific and functional antibodies against the human fibroblast growth factor receptor 3., PMID:12842902

A model for the generation of multiple A to G transitions in the human respiratory syncytial virus genome: predicted RNA secondary structures as substrates for adenosine deaminases that act on RNA., PMID:12029160

Datasheet
$ 220
Product specifications
50 μg 220 100 μg 350

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For research use only. Not for human or drug use.

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Anti-ADAR/IFI4 Antibody (R3N41) [RHF11403]
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