Anti-NUP98 Antibody (R3M98)

Catalog No.

RHE96602

Species reactivity

Human, Monkey

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, WB: 1:500-1:2000

Target

98 kDa nucleoporin, Nucleoporin Nup98, Nup98, Nuclear pore complex protein Nup98-Nup96, Nup96, Nucleoporin Nup96, ADAR2, 96 kDa nucleoporin, NUP98

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P52948

Applications

ELISA, FCM, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3M98

A checkpoint function for Nup98 in nuclear pore formation suggested by novel inhibitory nanobodies., PMID:38649536

Altered localization of nucleoporin 98 in primary tauopathies., PMID:36601621

Emerging Targeted Therapy for Specific Genomic Abnormalities in Acute Myeloid Leukemia., PMID:35216478

Acute Myeloid Leukemia in Children: Emerging Paradigms in Genetics and New Approaches to Therapy., PMID:33439382

Increased FGF-23 levels are linked to ineffective erythropoiesis and impaired bone mineralization in myelodysplastic syndromes., PMID:32759495

Disclosing the Interactome of Leukemogenic NUP98-HOXA9 and SET-NUP214 Fusion Proteins Using a Proteomic Approach., PMID:32664447

The Nuclear Pore Complex: A Target for NS3 Protease of Dengue and Zika Viruses., PMID:32466480

Roles of Nup133, Nup153 and membrane fenestrations in assembly of the nuclear pore complex at the end of mitosis., PMID:30821042

Progenitor B-1 B-cell acute lymphoblastic leukemia is associated with collaborative mutations in 3 critical pathways., PMID:29296821

Altered follicular helper T cell impaired antibody production in a murine model of myelodysplastic syndromes., PMID:29228688

Selective Removal of FG Repeat Domains from the Nuclear Pore Complex by Enterovirus 2A(pro)., PMID:26311873

The selection of mature B cells is critically dependent on the expression level of the co-receptor CD19., PMID:24472602

Monoclonal antibodies recognize gly-leu-phe-gly repeat of nucleoporin nup98 of tetrahymena, yeasts, and humans., PMID:23607342

A NUP98-HOXD13 leukemic fusion gene leads to impaired class switch recombination and antibody production., PMID:22613470

Domain topology of nucleoporin Nup98 within the nuclear pore complex., PMID:22100335

Nucleoporin98-96 function is required for transit amplification divisions in the germ line of Drosophila melanogaster., PMID:21949861

Colony forming cell (CFC) assay for human hematopoietic cells., PMID:21252854

Nup98 regulates bipolar spindle assembly through association with microtubules and opposition of MCAK., PMID:21209315

Specific monoclonal antibody against the nuclear pore complex protein, Nup96., PMID:21133806

Effects of the NUP98-DDX10 oncogene on primary human CD34+ cells: role of a conserved helicase motif., PMID:20339440

A new fusion gene NUP98-IQCG identified in an acute T-lymphoid/myeloid leukemia with a t(3;11)(q29q13;p15)del(3)(q29) translocation., PMID:18084320

Nuclear export assays for poly(A) RNAs., PMID:16935004

Specific monoclonal antibody against the nuclear pore complex protein, nup98., PMID:16225424

Identification of Ewing's sarcoma gene product as a glycoprotein using a monoclonal antibody that recognizes an immunodeterminant containing O-linked N-acetylglucosamine moiety., PMID:12193275

Interference with the cytoplasmic tail of gp210 disrupts "close apposition" of nuclear membranes and blocks nuclear pore dilation., PMID:12093788

Nup98 is a mobile nucleoporin with transcription-dependent dynamics., PMID:11950939

Tpr is localized within the nuclear basket of the pore complex and has a role in nuclear protein export., PMID:11839768

Novel vertebrate nucleoporins Nup133 and Nup160 play a role in mRNA export., PMID:11684705

The nucleoporin Nup98 associates with the intranuclear filamentous protein network of TPR., PMID:11248057

The mRNA export in Caenorhabditis elegans is mediated by Ce-NXF-1, an ortholog of human TAP/NXF and Saccharomyces cerevisiae Mex67p., PMID:11142376

The nucleoporin nup153 plays a critical role in multiple types of nuclear export., PMID:10069809

Identification and characterization of nuclear pore subcomplexes in mitotic extract of human somatic cells., PMID:9918853

RanGTP-mediated nuclear export of karyopherin alpha involves its interaction with the nucleoporin Nup153., PMID:9275187

Cloning and characterization of human karyopherin beta3., PMID:9114010

The vertebrate GLFG nucleoporin, Nup98, is an essential component of multiple RNA export pathways., PMID:9015297

The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complex., PMID:7736573

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