T-cell prolymphocytic leukemia, a case report and review of the literature., PMID:40109866
Inhibition of Kinase Activity and In Vitro Downregulation of the Protein Kinases in Lung Cancer and Cervical Cancer Cell Lines and the Identified Known Anticancer Compounds of Ziziphus mucronata., PMID:39942957
Rapid identification of primary atopic disorders (PAD) by a clinical landmark-guided, upfront use of genomic sequencing., PMID:39381601
STAT4 and STAT6, their role in cellular and humoral immunity and in diverse human diseases., PMID:39188021
Single-cell insights: pioneering an integrated atlas of chromatin accessibility and transcriptomic landscapes in diabetic cardiomyopathy., PMID:38664790
LFA-1 regulated by IL-2/STAT5 pathway boosts antitumor function of intratumoral CD8+ T cells for improving anti-PD-1 antibody therapy., PMID:38125721
JAK3 Y841 Autophosphorylation Is Critical for STAT5B Activation, Kinase Domain Stability and Dimer Formation., PMID:37569303
PAK1 overexpression promotes myxofibrosarcoma angiogenesis through STAT5B-mediated CSF2 transactivation: clinical and therapeutic relevance of amplification and nuclear entry., PMID:37564209
STAT5B restrains human B-cell differentiation to maintain humoral immune homeostasis., PMID:35469842
Combined Mutation of the GATA2 Gene and STAT5B Gene in a Patient with Hypogammaglobulinemia and Autoimmunity., PMID:34670919
A STAT5B-CD9 axis determines self-renewal in hematopoietic and leukemic stem cells., PMID:34320169
Dexamethasone reduces autoantibody levels in MRL/lpr mice by inhibiting Tfh cell responses., PMID:34318604
Stat5B is required for IgE-Mediated mast cell function in vitro and in vivo., PMID:33780747
Somatic mutations and T-cell clonality in patients with immunodeficiency., PMID:33256375
Immune Monitoring of Patients With Primary Immune Regulation Disorders Unravels Higher Frequencies of Follicular T Cells With Different Profiles That Associate With Alterations in B Cell Subsets., PMID:33193371
Phenotypic variability in a child with Felty's syndrome: a case report., PMID:32264838
Toll-like receptor 7 agonist imiquimod prevents the progression of SLE in MRL/lpr mice via inhibiting the differentiation of T follicular helper cells., PMID:32007709
T-cell large granular lymphocytic (LGL) leukemia consists of CD4+/CD8dim and CD4-/CD8+ LGL populations in association with immune thrombocytopenia, autoimmune neutropenia, and monoclonal B-cell lymphocytosis., PMID:31866622
Transcriptional Regulation of Nos2 via STAT5B Binding to Nos2 Gene Promoter Mediates Nitric Oxide Production: Relevance in β-Cell Maintenance., PMID:30790510
Genetic and Transcriptomic Variation Linked to Neutrophil Granulocyte-Macrophage Colony-Stimulating Factor Signaling in Pediatric Crohn's Disease., PMID:30124884
Dominant-negative STAT5B mutations cause growth hormone insensitivity with short stature and mild immune dysregulation., PMID:29844444
A type 1 diabetes genetic risk score can discriminate monogenic autoimmunity with diabetes from early-onset clustering of polygenic autoimmunity with diabetes., PMID:29417186
Advances in the understanding and management of T-cell prolymphocytic leukemia., PMID:29262669
Pathway analysis of global gene expression change in dendritic cells induced by the polysaccharide from the roots of Actinidia eriantha., PMID:29247698
STAT5B: A Differential Regulator of the Life and Death of CD4+ Effector Memory T Cells., PMID:29187589
The role of icaritin in regulating Foxp3/IL17a balance in systemic lupus erythematosus and its effects on the treatment of MRL/lpr mice., PMID:26604013
Differential Diagnosis of Genetic Disorders Associated with Moderate to Severe Refractory Eczema and Elevated Immunoglobulin E., PMID:26593686
Concurrent Mutations in ATM and Genes Associated with Common γ Chain Signaling in Peripheral T Cell Lymphoma., PMID:26536348
The Transcription Factor Ehf Is Involved in TGF-β-Induced Suppression of FcεRI and c-Kit Expression and FcεRI-Mediated Activation in Mast Cells., PMID:26297757
Long-term follow-up of STAT5B deficiency in three argentinian patients: clinical and immunological features., PMID:25753012
Decreased STAT3 in human idiopathic fetal growth restriction contributes to trophoblast dysfunction., PMID:25713425
The signal transducer and activator of transcription factors lodge in immunopathogenesis of rheumatoid arthritis., PMID:27215178
Regulatory T-cell deficiency and immune dysregulation, polyendocrinopathy, enteropathy, X-linked-like disorder caused by loss-of-function mutations in LRBA., PMID:25468195
BCR-ABL affects STAT5A and STAT5B differentially., PMID:24836440
Constitutive activation of STAT5A and STAT5B regulates IgM secretion in Waldenstrom's macroglobulinemia., PMID:24335105
Immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) and IPEX-related disorders: an evolving web of heritable autoimmune diseases., PMID:24240290
Genotype-dependent effects of TGF-β1 on mast cell function: targeting the Stat5 pathway., PMID:24068671
δ-opioid receptor activation leads to neurite outgrowth and neuronal differentiation via a STAT5B-Gαi/o pathway., PMID:23906478
Differential contributions of STAT5A and STAT5B to stress protection and tyrosine kinase inhibitor resistance of chronic myeloid leukemia stem/progenitor cells., PMID:23400594
Immune deficiency and autoimmunity., PMID:22820513
Signal transducer and activator of transcription 5b (Stat5b) serine 193 is a novel cytokine-induced phospho-regulatory site that is constitutively activated in primary hematopoietic malignancies., PMID:22442148
Screening of therapeutic targets for canine mast cell tumors from a variety of kinase molecules., PMID:21646751
Loss of nuclear localized and tyrosine phosphorylated Stat5 in breast cancer predicts poor clinical outcome and increased risk of antiestrogen therapy failure., PMID:21576635
Tissue factor-factor VIIa complex induces epithelial ovarian cancer cell invasion and metastasis through a monocytes-dependent mechanism., PMID:21543928
Evidence for a continuum of genetic, phenotypic, and biochemical abnormalities in children with growth hormone insensitivity., PMID:21525302
STAT-Related Profiles Are Associated with Patient Response to Targeted Treatments in Locally Advanced SCCHN., PMID:21286377
Genetic Defects in the Growth Hormone-IGF-I Axis Causing Growth Hormone Insensitivity and Impaired Linear Growth., PMID:22654835
Gammadelta T cells are reduced and rendered unresponsive by hyperglycemia and chronic TNFalpha in mouse models of obesity and metabolic disease., PMID:20625397
Oncoproteomic analysis reveals co-upregulation of RELA and STAT5 in carboplatin resistant ovarian carcinoma., PMID:20585448
Tyrosines 868, 966, and 972 in the kinase domain of JAK2 are autophosphorylated and required for maximal JAK2 kinase activity., PMID:20304997
For research use only. Not for human or drug use.
