Catalog No.
RHE82805
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a
Clonality
Monoclonal
Tested applications
FCM: 1:200-1:400, IF: 1:25-1:50, IHC: 1:200-1:400, WB: 1:500-1:1000
Target
hBRM, SNF2A, Protein brahma homolog, SMARCA2, ATP-dependent helicase SMARCA2, SNF2-alpha, BRM, BAF190B, BRG1-associated factor 190B, Probable global transcription activator SNF2L2, SNF2L2, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P51531
Applications
FCM, IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3M52
Unusual Aspects of Small Cell Carcinoma of the Ovary of Hypercalcaemic Type: Retained SMARCA4 Immunohistochemical Staining and Positive Staining With TLE1., PMID:37345679
SWI/SNF protein and claudin-4 expression in anaplastic carcinomas arising in mucinous tumours of the ovary and retroperitoneum., PMID:32268438
Loss of the SWI/SNF-ATPase subunit members SMARCF1 (ARID1A), SMARCA2 (BRM), SMARCA4 (BRG1) and SMARCB1 (INI1) in oesophageal adenocarcinoma., PMID:31906887
Inflammatory Arthritis as a Possible Feature of Coffin-Siris Syndrome., PMID:31243159
Long lasting major response to pembrolizumab in a thoracic malignant rhabdoid-like SMARCA4-deficient tumor., PMID:31114851
SWI/SNF protein expression status in fumarate hydratase-deficient renal cell carcinoma: immunohistochemical analysis of 32 tumors from 28 patients., PMID:29689242
Molecular hypotheses to explain the shared pathways and underlying pathobiological causes in catatonia and in catatonic presentations in neuropsychiatric disorders., PMID:29523295
Loss of Expression of a Novel Chromatin Remodeler SMARCA1 in Soft Tissue Sarcoma., PMID:31093468
The expression of the BRM and MMP2 genes in thoracic aortic aneurysm and aortic dissection., PMID:28678310
B-Lymphoblastic Lymphomas Evolving from Follicular Lymphomas Co-Express Surrogate Light Chains and Mutated Gamma Heavy Chains., PMID:27750045
Loss of expression of the SWI/SNF complex is a frequent event in undifferentiated/dedifferentiated urothelial carcinoma of the urinary tract., PMID:27339451
AICAR sustains J1 mouse embryonic stem cell self-renewal and pluripotency by regulating transcription factor and epigenetic modulator expression., PMID:23988673
A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1., PMID:23872584
Oncogenic targeting of BRM drives malignancy through C/EBPβ-dependent induction of α5 integrin., PMID:23770848
The clinical significance of SWI/SNF complex in pancreatic cancer., PMID:23229642
ICF, an immunodeficiency syndrome: DNA methyltransferase 3B involvement, chromosome anomalies, and gene dysregulation., PMID:18432406
Aberrant expression of SWI/SNF catalytic subunits BRG1/BRM is associated with tumor development and increased invasiveness in prostate cancers., PMID:17075831
UV laser cross-linking: a real-time assay to study dynamic protein/DNA interactions during chromatin remodeling., PMID:15507594
Two related ARID family proteins are alternative subunits of human SWI/SNF complexes., PMID:15170388
A conserved truncated isoform of the ATR-X syndrome protein lacking the SWI/SNF-homology domain., PMID:14729260
The p400 complex is an essential E1A transformation target., PMID:11509179
The human SWI/SNF-B chromatin-remodeling complex is related to yeast rsc and localizes at kinetochores of mitotic chromosomes., PMID:11078522
Mutations in ATRX, encoding a SWI/SNF-like protein, cause diverse changes in the pattern of DNA methylation., PMID:10742099
Differential preimplantation regulation of two mouse homologues of the yeast SWI2 protein., PMID:9603422
Components of the human SWI/SNF complex are enriched in active chromatin and are associated with the nuclear matrix., PMID:9128241
Purification and biochemical heterogeneity of the mammalian SWI-SNF complex., PMID:8895581
The hbrm and BRG-1 proteins, components of the human SNF/SWI complex, are phosphorylated and excluded from the condensed chromosomes during mitosis., PMID:8670841
Cloning of an SNF2/SWI2-related protein that binds specifically to the SPH motifs of the SV40 enhancer and to the HIV-1 promoter., PMID:7876228
For research use only. Not for human or drug use.
