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Anti-BLK Antibody (R3M49)

Catalog #:   RHE81701 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: FCM, IF
Accession: P51451
Overview

Catalog No.

RHE81701

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

FCM: 1:200-1:400, IF: 1:200-1:1000

Target

Tyrosine-protein kinase Blk, BLK, p55-Blk, B lymphocyte kinase

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P51451

Applications

FCM, IF

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3M49

Data Image
  • Flow Cytometry
    Flow cytometric analysis of HL-60 cells using BLK mouse mAb (green) and negative control (purple).
  • Immunofluorescence
    Immunofluorescence analysis of Hela cells using BLK mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
References

Delphi Survey on Measurable Residual Disease in Multiple Myeloma: Prevailing Practices and the Way Forward in India., PMID:40514308

Genotype, Phenotype, and Clinical Characteristics of Maturity-onset Diabetes of the Young (MODY): Predominance of GCK-MODY., PMID:40338033

Evaluation of tumorous LCP1 and ADPGK as predictive biomarker for immune-related adverse events in bone and soft tissue sarcomas treated with anti-PD-1 and anti-PD-L1 antibodies., PMID:40189514

Omalizumab with allergen immunotherapy in respiratory & food allergy., PMID:39890381

Anti-Idiotypic Antibody as a Booster Vaccine Against Respiratory Syncytial Virus., PMID:39852814

Can computer crossmatch really replace antihuman globulin crossmatch? An intriguing case of missing anti-c on routine antibody screen from a multispecialty center in India., PMID:39822698

Epidermal growth factor receptors unveiled: a comprehensive survey on mutations, clinical insights of global inhibitors, and emergence of heterocyclic derivatives as EGFR inhibitors., PMID:39756062

How intravitreal anti-vascular endothelial growth factor initial dosing impacts patient outcomes in diabetic macular oedema., PMID:39736584

Molecular Imaging of Tumor-Infiltrating Lymphocytes in Living Animals Using a Novel mCD3 Fibronectin Scaffold., PMID:39681342

Molecular and clinical profiles of pediatric monogenic diabetes subtypes: comprehensive genetic analysis of 138 patients., PMID:39504571

Forimtamig, a novel GPRC5D-targeting T-cell bispecific antibody with a 2+1 format, for the treatment of multiple myeloma., PMID:39476124

Detection of host cell microprotein impurities in antibody drug products., PMID:39366928

Paroxysmal Cold Hemoglobinuria: Mild to Catastrophic-Spectrum of a Rare Hemolytic Anemia of Childhood., PMID:39324966

Autoimmune Encephalitis: A Hidden Enigma Demystified., PMID:38990591

A Genome-Wide Association Study Suggests New Susceptibility Loci for Primary Antiphospholipid Syndrome., PMID:38973605

Splenic marginal zone B cells restrict Mycobacterium tuberculosis infection by shaping the cytokine pattern and cell-mediated immunity., PMID:38959109

Altered Expression of B Cell Receptor Signaling Pathway Genes in Peripheral Blood of Patients with Multiple Sclerosis., PMID:38822513

Safety, immunogenicity and efficacy of the self-amplifying mRNA ARCT-154 COVID-19 vaccine: pooled phase 1, 2, 3a and 3b randomized, controlled trials., PMID:38744844

A genome-wide association study suggests new susceptibility loci for primary antiphospholipid syndrome., PMID:38405993

Placenta microRNA profile of patient with Obstetric Antiphospholipid Syndrome., PMID:38155384

Screening of Mutations in Maturity-onset Diabetes of the Young-related Genes and RFX6 in Children with Autoantibody-negative Type 1 Diabetes Mellitus., PMID:38054414

Label-free virtual staining of neutrophil extracellular traps (NETs) in microfluidics., PMID:37584074

Multifaceted Spindle Cell/Sclerosing Rhabdomyosarcoma With Role of Immunohistochemistry in Avoiding Misdiagnosis: A Multi-Institutional Study of 45 Distinct Tumors., PMID:37489265

Label-free microfluidic cell sorting and detection for rapid blood analysis., PMID:36655549

Study of the frequency and clinical features of maturity-onset diabetes in the young in the pediatric and adolescent diabetes population in Iran., PMID:36100423

A rapid simple point-of-care assay for the detection of SARS-CoV-2 neutralizing antibodies., PMID:35602218

Development and validation of novel kit for quantification of SARS-CoV-2 antibodies on clinical samples., PMID:34919976

COVID-19-associated Multisystem Inflammatory Syndrome in Children: A Multicentric Retrospective Cohort Study., PMID:34916752

Prospective multi-centric study to analyze pre-transplant compatibility algorithm for live-related donor kidney transplant in Indian setting: the "Delhi approach"!, PMID:34688882

Case of Hemolytic Disease of the Newborn due to a Rare Red Cell Antibody., PMID:34599067

Assessment of genetic polymorphisms within nuclear factor-κB signaling pathway genes in rheumatoid arthritis: Evidence for replication and genetic interaction., PMID:34464884

Paraneoplastic cerebellar degeneration as a presenting manifestation of non-Hodgkin's lymphoma., PMID:33555484

Immunity certification for COVID-19: ethical considerations., PMID:33551509

Abnormal thymic B cell activation and impaired T cell differentiation in pristane-induced lupus mice., PMID:33428991

Src Family Protein Kinase Controls the Fate of B Cells in Autoimmune Diseases., PMID:33037966

Association between Neu5Gc carbohydrate and serum antibodies against it provides the molecular link to cancer: French NutriNet-Santé study., PMID:32962714

B Cell Disorders in Children: Part II., PMID:32821980

Clinical and laboratory clues of maturity-onset diabetes of the young and determination of association with molecular diagnosis., PMID:32710514

Indian National Association for the Study of the Liver Consensus Statement on Acute Liver Failure (Part 1): Epidemiology, Pathogenesis, Presentation and Prognosis., PMID:32655238

Survey of ex vivo drug combination effects in chronic lymphocytic leukemia reveals synergistic drug effects and genetic dependencies., PMID:32404973

Long-term outcomes of IMiD-based trials in patients with immunoglobulin light-chain amyloidosis: a pooled analysis., PMID:31913261

Destabilization of ROR1 enhances activity of Ibrutinib against chronic lymphocytic leukemia in vivo., PMID:31726100

Lung endothelial cell antigen cross-presentation to CD8+T cells drives malaria-associated lung injury., PMID:31534124

An OMICS-based study of the role of C3dg in keratinocytes: RNA sequencing, antibody-chip array, and bioinformatics approaches., PMID:30974145

Gene expression profiling of lichenoid dermatitis immune-related adverse event from immune checkpoint inhibitors reveals increased CD14+ and CD16+ monocytes driving an innate immune response., PMID:30883858

Immunoglobulin G4 related pancreaticobiliary disease: Report of two cases highlighting the diagnostic criteria., PMID:30706866

Associations of secreted phosphoprotein 1 and B lymphocyte kinase gene polymorphisms with autoimmune thyroid disease., PMID:30589937

A Novel Engineered Small Protein for Positron Emission Tomography Imaging of Human Programmed Death Ligand-1: Validation in Mouse Models and Human Cancer Tissues., PMID:30373750

Pan-SRC kinase inhibition blocks B-cell receptor oncogenic signaling in non-Hodgkin lymphoma., PMID:29567799

Dosimetry Prediction for Clinical Translation of 64Cu-Pembrolizumab ImmunoPET Targeting Human PD-1 Expression., PMID:29330552

Datasheet

Document Download

Anti-BLK Antibody (R3M49).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-BLK Antibody (R3M49) [RHE81701]
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