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Anti-CTCF Antibody (R3L93)

Catalog #:   RHE68303 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: WB
Accession: P49711
Overview

Catalog No.

RHE68303

Species reactivity

Human, Monkey

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

WB: 1:500-1:2000

Target

Transcriptional repressor CTCF, CTCF, CCCTC-binding factor, 11-zinc finger protein, CTCFL paralog

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P49711

Applications

WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3L93

Data Image
  • Western blot
    Western blot analysis using CTCF mouse mAb against A31 (1), MCF-7 (2), Hela (3), HCT116 (4), Jurkat (5), NIH/3T3 (6), and Cos7 (7) cell lysate.
References

Defining three dimensional chromatin structures of pediatric and adolescent B cells using primary B cell and EBV-immortalized B cell reference genomes., PMID:40437445

Interplay between CTCF-binding and CTCF-lacking regulatory elements in generating an architectural stripe at the Igh locus., PMID:40032827

CTGF (CCN2): a multifaceted mediator in breast cancer progression and therapeutic targeting., PMID:39945880

Single-cell mapping of regulatory DNA:Protein interactions., PMID:39803441

ZNF143 is a transcriptional regulator of nuclear-encoded mitochondrial genes that acts independently of looping and CTCF., PMID:39708805

Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development., PMID:39627609

Nuclear translocation of SIRT4 mediates deacetylation of U2AF2 to modulate renal fibrosis through alternative splicing-mediated upregulation of CCN2., PMID:39495216

CD248-expressing cancer-associated fibroblasts induce non-small cell lung cancer metastasis via Hippo pathway-mediated extracellular matrix stiffness., PMID:39164826

Molecular basis for differential Igk versus Igh V(D)J joining mechanisms., PMID:38811728

G-quadruplex landscape and its regulation revealed by a new antibody capture method., PMID:38484151

CTGF regulates mineralization in human mature chondrocyte by controlling Pit-1 and modulating ANK via the BMP/Smad signalling., PMID:38134555

Comparison of the three-dimensional chromatin structures of adolescent and adult peripheral blood B cells: implications for the study of pediatric autoimmune diseases., PMID:37745336

Chromatin Immunoprecipitation from Formaldehyde Cross-Linked Olfactory Sensory Neurons., PMID:37688725

Contribution of the IGCR1 regulatory element and the 3'Igh CTCF-binding elements to regulation of Igh V(D)J recombination., PMID:37339228

CCCTC-binding factor: the specific transcription factor of β-galactoside α-2,6-sialyltransferase 1 that upregulates the sialylation of anti-citrullinated protein antibodies in rheumatoid arthritis., PMID:37326830

Contribution of the IGCR1 regulatory element and the 3 'Igh CBEs to Regulation of Igh V(D)J Recombination., PMID:37163018

Knockout of miR-184 in zebrafish leads to ocular abnormalities by elevating p21 levels., PMID:37086087

A de novo transcription-dependent TAD boundary underpins critical multiway interactions during antibody class switch recombination., PMID:36736317

Is there a relationship between infertility and fertilin β protein distribution?, PMID:35933293

ProbC: joint modeling of epigenome and transcriptome effects in 3D genome., PMID:35397520

The role of chromatin loop extrusion in antibody diversification., PMID:35169260

Systematic identification of genomic elements that regulate FCGR2A expression and harbor variants linked with autoimmune disease., PMID:34970970

RedChIP identifies noncoding RNAs associated with genomic sites occupied by Polycomb and CTCF proteins., PMID:34969862

Soluble very low-density lipoprotein receptor (sVLDLR) inhibits fibrosis in neovascular age-related macular degeneration., PMID:34820908

The protective effects of pericyte-derived microvesicles on vascular endothelial functions via CTGF delivery in sepsis., PMID:34784912

Endothelial cell-derived pro-fibrotic factors increase TGF-β1 expression by smooth muscle cells in response to cycles of hypoxia-hyperoxia., PMID:34601016

Visualizing looping of two endogenous genomic loci using synthetic zinc-finger proteins with anti-FLAG and anti-HA frankenbodies in living cells., PMID:34465007

Early glutathione intervention educed positive correlation between VGLUT1 expression and spatial memory in the Nω-nitro-L-arginine methyl rat model of IUGR., PMID:34179867

Dysregulation of PI3K and Hippo signaling pathways synergistically induces chronic pancreatitis via CTGF upregulation., PMID:34032634

Intravitreal connective tissue growth factor neutralizing antibody or bevacizumab alone or in combination for prevention of proliferative vitreoretinopathy in an experimental model., PMID:34022176

Panorama of stepwise involvement of the IgH 3' regulatory region in murine B cells., PMID:33993921

Expression and localization of FGFR1, FGFR2 and CTGF during normal human lung development., PMID:33962151

ZNF213 negatively controls triple negative breast cancer progression via Hippo/YAP signaling., PMID:33939216

Dynamic 3D Locus Organization and Its Drivers Underpin Immunoglobulin Recombination., PMID:33679727

Knockdown of AKT3 Activates HER2 and DDR Kinases in Bone-Seeking Breast Cancer Cells, Promotes Metastasis In Vivo and Attenuates the TGFβ/CTGF Axis., PMID:33670586

Loop extrusion mediates physiological Igh locus contraction for RAG scanning., PMID:33442057

Physiological role of the 3'IgH CBEs super-anchor in antibody class switching., PMID:33441485

How DNA loop extrusion mediated by cohesin enables V(D)J recombination., PMID:33422934

Targeting CTGF in Cancer: An Emerging Therapeutic Opportunity., PMID:33358571

Binding of CCCTC-Binding Factor (CTCF) to the Minute Virus of Mice Genome Is Important for Proper Processing of Viral P4-Generated Pre-mRNAs., PMID:33266080

Down-regulation of Exosomal miR-214-3p Targeting CCN2 Contributes to Endometriosis Fibrosis and the Role of Exosomes in the Horizontal Transfer of miR-214-3p., PMID:33048316

A dichotomy of gene regulatory associations during the activated B-cell to plasmablast transition., PMID:32843533

Connective tissue growth factor produced by cancer‑associated fibroblasts correlates with poor prognosis in epithelioid malignant pleural mesothelioma., PMID:32705221

Pamrevlumab for the treatment of idiopathic pulmonary fibrosis., PMID:32447983

Long Noncoding RNAs Control the Modulation of Immune Checkpoint Molecules in Cancer., PMID:32321773

Noncoding RNA transcription alters chromosomal topology to promote isotype-specific class switch recombination., PMID:32034089

HTLV-1 CTCF-binding site is dispensable for in vitro immortalization and persistent infection in vivo., PMID:31864373

Fundamental roles of chromatin loop extrusion in antibody class switching., PMID:31666703

Expression of connective tissue growth factor as a prognostic indicator and its possible involvement in the aggressive properties of epithelial ovarian carcinoma., PMID:31578579

Mycobacterium tuberculosis induces connective tissue growth factor expression through the TLR2-JNK-AP-1 pathway in human lung fibroblasts., PMID:31451010

Datasheet

Document Download

Anti-CTCF Antibody (R3L93).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-CTCF Antibody (R3L93) [RHE68303]
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