Catalog No.
RHE68303
Species reactivity
Human, Monkey
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
WB: 1:500-1:2000
Target
Transcriptional repressor CTCF, CTCF, CCCTC-binding factor, 11-zinc finger protein, CTCFL paralog
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P49711
Applications
WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3L93
Defining three dimensional chromatin structures of pediatric and adolescent B cells using primary B cell and EBV-immortalized B cell reference genomes., PMID:40437445
Interplay between CTCF-binding and CTCF-lacking regulatory elements in generating an architectural stripe at the Igh locus., PMID:40032827
CTGF (CCN2): a multifaceted mediator in breast cancer progression and therapeutic targeting., PMID:39945880
Single-cell mapping of regulatory DNA:Protein interactions., PMID:39803441
ZNF143 is a transcriptional regulator of nuclear-encoded mitochondrial genes that acts independently of looping and CTCF., PMID:39708805
Dynamic O-GlcNAcylation governs long-range chromatin interactions in V(D)J recombination during early B-cell development., PMID:39627609
Nuclear translocation of SIRT4 mediates deacetylation of U2AF2 to modulate renal fibrosis through alternative splicing-mediated upregulation of CCN2., PMID:39495216
CD248-expressing cancer-associated fibroblasts induce non-small cell lung cancer metastasis via Hippo pathway-mediated extracellular matrix stiffness., PMID:39164826
Molecular basis for differential Igk versus Igh V(D)J joining mechanisms., PMID:38811728
G-quadruplex landscape and its regulation revealed by a new antibody capture method., PMID:38484151
CTGF regulates mineralization in human mature chondrocyte by controlling Pit-1 and modulating ANK via the BMP/Smad signalling., PMID:38134555
Comparison of the three-dimensional chromatin structures of adolescent and adult peripheral blood B cells: implications for the study of pediatric autoimmune diseases., PMID:37745336
Chromatin Immunoprecipitation from Formaldehyde Cross-Linked Olfactory Sensory Neurons., PMID:37688725
Contribution of the IGCR1 regulatory element and the 3'Igh CTCF-binding elements to regulation of Igh V(D)J recombination., PMID:37339228
CCCTC-binding factor: the specific transcription factor of β-galactoside α-2,6-sialyltransferase 1 that upregulates the sialylation of anti-citrullinated protein antibodies in rheumatoid arthritis., PMID:37326830
Contribution of the IGCR1 regulatory element and the 3 'Igh CBEs to Regulation of Igh V(D)J Recombination., PMID:37163018
Knockout of miR-184 in zebrafish leads to ocular abnormalities by elevating p21 levels., PMID:37086087
A de novo transcription-dependent TAD boundary underpins critical multiway interactions during antibody class switch recombination., PMID:36736317
Is there a relationship between infertility and fertilin β protein distribution?, PMID:35933293
ProbC: joint modeling of epigenome and transcriptome effects in 3D genome., PMID:35397520
The role of chromatin loop extrusion in antibody diversification., PMID:35169260
Systematic identification of genomic elements that regulate FCGR2A expression and harbor variants linked with autoimmune disease., PMID:34970970
RedChIP identifies noncoding RNAs associated with genomic sites occupied by Polycomb and CTCF proteins., PMID:34969862
Soluble very low-density lipoprotein receptor (sVLDLR) inhibits fibrosis in neovascular age-related macular degeneration., PMID:34820908
The protective effects of pericyte-derived microvesicles on vascular endothelial functions via CTGF delivery in sepsis., PMID:34784912
Endothelial cell-derived pro-fibrotic factors increase TGF-β1 expression by smooth muscle cells in response to cycles of hypoxia-hyperoxia., PMID:34601016
Visualizing looping of two endogenous genomic loci using synthetic zinc-finger proteins with anti-FLAG and anti-HA frankenbodies in living cells., PMID:34465007
Early glutathione intervention educed positive correlation between VGLUT1 expression and spatial memory in the Nω-nitro-L-arginine methyl rat model of IUGR., PMID:34179867
Dysregulation of PI3K and Hippo signaling pathways synergistically induces chronic pancreatitis via CTGF upregulation., PMID:34032634
Intravitreal connective tissue growth factor neutralizing antibody or bevacizumab alone or in combination for prevention of proliferative vitreoretinopathy in an experimental model., PMID:34022176
Panorama of stepwise involvement of the IgH 3' regulatory region in murine B cells., PMID:33993921
Expression and localization of FGFR1, FGFR2 and CTGF during normal human lung development., PMID:33962151
ZNF213 negatively controls triple negative breast cancer progression via Hippo/YAP signaling., PMID:33939216
Dynamic 3D Locus Organization and Its Drivers Underpin Immunoglobulin Recombination., PMID:33679727
Knockdown of AKT3 Activates HER2 and DDR Kinases in Bone-Seeking Breast Cancer Cells, Promotes Metastasis In Vivo and Attenuates the TGFβ/CTGF Axis., PMID:33670586
Loop extrusion mediates physiological Igh locus contraction for RAG scanning., PMID:33442057
Physiological role of the 3'IgH CBEs super-anchor in antibody class switching., PMID:33441485
How DNA loop extrusion mediated by cohesin enables V(D)J recombination., PMID:33422934
Targeting CTGF in Cancer: An Emerging Therapeutic Opportunity., PMID:33358571
Binding of CCCTC-Binding Factor (CTCF) to the Minute Virus of Mice Genome Is Important for Proper Processing of Viral P4-Generated Pre-mRNAs., PMID:33266080
Down-regulation of Exosomal miR-214-3p Targeting CCN2 Contributes to Endometriosis Fibrosis and the Role of Exosomes in the Horizontal Transfer of miR-214-3p., PMID:33048316
A dichotomy of gene regulatory associations during the activated B-cell to plasmablast transition., PMID:32843533
Connective tissue growth factor produced by cancer‑associated fibroblasts correlates with poor prognosis in epithelioid malignant pleural mesothelioma., PMID:32705221
Pamrevlumab for the treatment of idiopathic pulmonary fibrosis., PMID:32447983
Long Noncoding RNAs Control the Modulation of Immune Checkpoint Molecules in Cancer., PMID:32321773
Noncoding RNA transcription alters chromosomal topology to promote isotype-specific class switch recombination., PMID:32034089
HTLV-1 CTCF-binding site is dispensable for in vitro immortalization and persistent infection in vivo., PMID:31864373
Fundamental roles of chromatin loop extrusion in antibody class switching., PMID:31666703
Expression of connective tissue growth factor as a prognostic indicator and its possible involvement in the aggressive properties of epithelial ovarian carcinoma., PMID:31578579
Mycobacterium tuberculosis induces connective tissue growth factor expression through the TLR2-JNK-AP-1 pathway in human lung fibroblasts., PMID:31451010
For research use only. Not for human or drug use.
