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Anti-P2RY1 Antibody (R3L62)

Catalog #:   RHE53101 Specific References (37) DATASHEET
Host species: Mouse
Isotype: IgG2b
Applications: ELISA, FCM, IHC
Accession: P47900
Overview

Catalog No.

RHE53101

Species reactivity

Human

Host species

Mouse

Isotype

IgG2b

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, IHC: 1:200-1:1000

Target

Purinergic receptor, P2Y1, P2RY1, P2Y purinoceptor 1, ADP receptor

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P47900

Applications

ELISA, FCM, IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3L62

Data Image
  • Flow Cytometry
    Flow cytometric analysis of Hela cells using P2RY1 mouse mAb (green) and negative control (red).
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human bladder cancer tissues using P2RY1 mouse mAb with DAB staining.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using P2RY1 mouse mAb with DAB staining.
References

Cyclic tensile force stimulates BMP9 synthesis and in vitro mineralization by human periodontal ligament cells., PMID:30206934

Characterization of a novel function-blocking antibody targeted against the platelet P2Y1 receptor., PMID:25593131

Expression of astrocyte-related receptors in cortical dysplasia with intractable epilepsy., PMID:25003238

Purinergic inhibitory regulation of murine detrusor muscles mediated by PDGFRα+ interstitial cells., PMID:24396055

Activity-dependent neuron-glial signaling by ATP and leukemia-inhibitory factor promotes hippocampal glial cell development., PMID:19267953

Potential role of purinergic signaling in lithium-induced nephrogenic diabetes insipidus., PMID:19244398

Articular chondrocytes express connexin 43 hemichannels and P2 receptors - a putative mechanoreceptor complex involving the primary cilium?, PMID:19207989

Innervation and receptor profiles of the human apocrine (epitrichial) sweat gland: routes for intervention in bromhidrosis., PMID:18637900

Deficiency of purinergic P2Y receptors in aganglionic intestine in Hirschsprung's disease., PMID:17962960

Glycoprotein Ibalpha inhibition and ADP receptor antagonists, but not aspirin, reduce platelet thrombus formation in flowing blood exposed to atherosclerotic plaques., PMID:17334511

Enhanced food intake after stimulation of hypothalamic P2Y1 receptors in rats: modulation of feeding behaviour by extracellular nucleotides., PMID:17067301

Distinct clathrin-coated pits sort different G protein-coupled receptor cargo., PMID:16899088

Extracellular adenine nucleotides inhibit the release of major monocyte recruiters by human monocyte-derived dendritic cells., PMID:16413542

Differential coupling of the P2Y1 receptor to Galpha14 and Galphaq/11 proteins during the development of the rat salivary gland., PMID:16336941

Identification of P2Y receptor subtypes in human muller glial cells by physiology, single cell RT-PCR, and immunohistochemistry., PMID:16043877

Thrombopoietin complements G(i)- but not G(q)-dependent pathways for integrin {alpha}(IIb){beta}(3) activation and platelet aggregation., PMID:15863506

ATP excites interneurons and astrocytes to increase synaptic inhibition in neuronal networks., PMID:15456834

P2X2 and P2Y1 immunofluorescence in rat neostriatal medium-spiny projection neurones and cholinergic interneurones is not linked to respective purinergic receptor function., PMID:15345659

Synergistic action between inhibition of P2Y12/P2Y1 and P2Y12/thrombin in ADP- and thrombin-induced human platelet activation., PMID:15265806

Differential effects of P2Y1 and P2Y12 nucleotide receptors on ERK1/ERK2 and phosphatidylinositol 3-kinase signalling and cell proliferation in serum-deprived and nonstarved glioma C6 cells., PMID:14718252

Purinergic receptors are part of a signaling system for keratinocyte proliferation, differentiation, and apoptosis in human fetal epidermis., PMID:14708618

The relative importance of the ADP receptors, P2Y12 and P2Y1, in thrombin-induced platelet activation., PMID:14644082

The pattern of distribution of selected ATP-sensitive P2 receptor subtypes in normal rat kidney: an immunohistological study., PMID:14605489

Localisation of P2Y1 and P2Y4 receptors in dorsal root, nodose and trigeminal ganglia of the rat., PMID:14564529

Thrombin-induced platelet PAR4 activation: role of glycoprotein Ib and ADP., PMID:12871418

P2X and P2Y purinoceptor expression in pancreas from streptozotocin-diabetic rats., PMID:12850289

Activation of delta opioid receptors induces receptor insertion and neuropeptide secretion., PMID:12526778

Hetero-oligomerization of adenosine A1 receptors with P2Y1 receptors in rat brains., PMID:12417330

Immunolocalization of P2Y1 and TPalpha receptors in platelets showed a major pool associated with the membranes of alpha -granules and the open canalicular system., PMID:12393588

Distinct roles of GPVI and integrin alpha(2)beta(1) in platelet shape change and aggregation induced by different collagens., PMID:12183336

Purinergic receptor expression in the apical plasma membrane of rat uterine epithelial cells during implantation., PMID:12098222

Role of the PAR4 thrombin receptor in stabilizing platelet-platelet aggregates as revealed by a patient with Hermansky-Pudlak syndrome., PMID:12008957

Extracellular ATP signaling and P2X nucleotide receptors in monolayers of primary human vascular endothelial cells., PMID:11788340

Adenosine diphosphate (ADP)-induced thromboxane A(2) generation in human platelets requires coordinated signaling through integrin alpha(IIb)beta(3) and ADP receptors., PMID:11756171

An RGD sequence in the P2Y(2) receptor interacts with alpha(V)beta(3) integrins and is required for G(o)-mediated signal transduction., PMID:11331301

Immunohistochemical localization of the P2Y(1) purinergic receptor in neurons and glial cells of the central nervous system., PMID:10891584

Regional and cellular distribution of the P2Y(1) purinergic receptor in the human brain: striking neuronal localisation., PMID:10813793

Datasheet

Document Download

Anti-P2RY1 Antibody (R3L62).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-P2RY1 Antibody (R3L62) [RHE53101]
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