Catalog No.
RHE53102
Species reactivity
Human, Rat
Host species
Mouse
Isotype
IgG2b
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IHC: 1:200-1:1000, WB: 1:500-1:2000
Target
Purinergic receptor, P2Y1, P2RY1, P2Y purinoceptor 1, ADP receptor
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P47900
Applications
ELISA, FCM, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3L61
Cyclic tensile force stimulates BMP9 synthesis and in vitro mineralization by human periodontal ligament cells., PMID:30206934
Characterization of a novel function-blocking antibody targeted against the platelet P2Y1 receptor., PMID:25593131
Expression of astrocyte-related receptors in cortical dysplasia with intractable epilepsy., PMID:25003238
Purinergic inhibitory regulation of murine detrusor muscles mediated by PDGFRα+ interstitial cells., PMID:24396055
Activity-dependent neuron-glial signaling by ATP and leukemia-inhibitory factor promotes hippocampal glial cell development., PMID:19267953
Potential role of purinergic signaling in lithium-induced nephrogenic diabetes insipidus., PMID:19244398
Articular chondrocytes express connexin 43 hemichannels and P2 receptors - a putative mechanoreceptor complex involving the primary cilium?, PMID:19207989
Innervation and receptor profiles of the human apocrine (epitrichial) sweat gland: routes for intervention in bromhidrosis., PMID:18637900
Deficiency of purinergic P2Y receptors in aganglionic intestine in Hirschsprung's disease., PMID:17962960
Glycoprotein Ibalpha inhibition and ADP receptor antagonists, but not aspirin, reduce platelet thrombus formation in flowing blood exposed to atherosclerotic plaques., PMID:17334511
Enhanced food intake after stimulation of hypothalamic P2Y1 receptors in rats: modulation of feeding behaviour by extracellular nucleotides., PMID:17067301
Distinct clathrin-coated pits sort different G protein-coupled receptor cargo., PMID:16899088
Extracellular adenine nucleotides inhibit the release of major monocyte recruiters by human monocyte-derived dendritic cells., PMID:16413542
Differential coupling of the P2Y1 receptor to Galpha14 and Galphaq/11 proteins during the development of the rat salivary gland., PMID:16336941
Identification of P2Y receptor subtypes in human muller glial cells by physiology, single cell RT-PCR, and immunohistochemistry., PMID:16043877
Thrombopoietin complements G(i)- but not G(q)-dependent pathways for integrin {alpha}(IIb){beta}(3) activation and platelet aggregation., PMID:15863506
ATP excites interneurons and astrocytes to increase synaptic inhibition in neuronal networks., PMID:15456834
P2X2 and P2Y1 immunofluorescence in rat neostriatal medium-spiny projection neurones and cholinergic interneurones is not linked to respective purinergic receptor function., PMID:15345659
Synergistic action between inhibition of P2Y12/P2Y1 and P2Y12/thrombin in ADP- and thrombin-induced human platelet activation., PMID:15265806
Differential effects of P2Y1 and P2Y12 nucleotide receptors on ERK1/ERK2 and phosphatidylinositol 3-kinase signalling and cell proliferation in serum-deprived and nonstarved glioma C6 cells., PMID:14718252
Purinergic receptors are part of a signaling system for keratinocyte proliferation, differentiation, and apoptosis in human fetal epidermis., PMID:14708618
The relative importance of the ADP receptors, P2Y12 and P2Y1, in thrombin-induced platelet activation., PMID:14644082
The pattern of distribution of selected ATP-sensitive P2 receptor subtypes in normal rat kidney: an immunohistological study., PMID:14605489
Localisation of P2Y1 and P2Y4 receptors in dorsal root, nodose and trigeminal ganglia of the rat., PMID:14564529
Thrombin-induced platelet PAR4 activation: role of glycoprotein Ib and ADP., PMID:12871418
P2X and P2Y purinoceptor expression in pancreas from streptozotocin-diabetic rats., PMID:12850289
Activation of delta opioid receptors induces receptor insertion and neuropeptide secretion., PMID:12526778
Hetero-oligomerization of adenosine A1 receptors with P2Y1 receptors in rat brains., PMID:12417330
Immunolocalization of P2Y1 and TPalpha receptors in platelets showed a major pool associated with the membranes of alpha -granules and the open canalicular system., PMID:12393588
Distinct roles of GPVI and integrin alpha(2)beta(1) in platelet shape change and aggregation induced by different collagens., PMID:12183336
Purinergic receptor expression in the apical plasma membrane of rat uterine epithelial cells during implantation., PMID:12098222
Role of the PAR4 thrombin receptor in stabilizing platelet-platelet aggregates as revealed by a patient with Hermansky-Pudlak syndrome., PMID:12008957
Extracellular ATP signaling and P2X nucleotide receptors in monolayers of primary human vascular endothelial cells., PMID:11788340
Adenosine diphosphate (ADP)-induced thromboxane A(2) generation in human platelets requires coordinated signaling through integrin alpha(IIb)beta(3) and ADP receptors., PMID:11756171
An RGD sequence in the P2Y(2) receptor interacts with alpha(V)beta(3) integrins and is required for G(o)-mediated signal transduction., PMID:11331301
Immunohistochemical localization of the P2Y(1) purinergic receptor in neurons and glial cells of the central nervous system., PMID:10891584
Regional and cellular distribution of the P2Y(1) purinergic receptor in the human brain: striking neuronal localisation., PMID:10813793