Anti-CCR10 Antibody (R3L49)

Catalog No.

RHE47001

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000, IHC: 1:200-1:1000

Target

C-C chemokine receptor type 10, G-protein coupled receptor 2, CCR-10, CC-CKR-10, GPR2, CCR10, C-C CKR-10

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P46092

Applications

ELISA, FCM, IF, IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3L49

Infant respiratory infections modulate lymphocyte homing to breast milk., PMID:39867906

Bone Marrow-Derived GCA+ Immune Cells Drive Alzheimer's Disease Progression., PMID:37949676

Cross-talk between Myeloid and B Cells Shapes the Distinct Microenvironments of Primary and Secondary Liver Cancer., PMID:37352379

IgE-binding monocytes upregulate the coagulation cascade in allergic horses., PMID:37193769

Plasmablasts in previously immunologically naïve COVID-19 patients express markers indicating mucosal homing and secrete antibodies cross-reacting with SARS-CoV-2 variants and other beta-coronaviruses., PMID:37071584

Expression of Homing Receptors in IgM+IgD+CD27+ B Cells and Their Frequencies in Appendectomized and/or Tonsillectomized Individuals., PMID:36943113

Mahuang Xixin Fuzi decoction protects the BALB/c-nude mice infected with influenza A virus by reducing inflammatory cytokines storm and weakly regulating SIgA immune response., PMID:36549371

[Role of the CCL28-CCR10 pathway in monocyte migration in rheumatoid arthritis]., PMID:36533335

Unraveling the surface proteomic profile of multiple myeloma to reveal new immunotherapeutic targets and markers of drug resistance., PMID:36311892

Distepharinamide, a novel dimeric proaporphine alkaloid from Diploclisia glaucescens, inhibits the differentiation and proliferative expansion of CD4+Foxp3+ regulatory T cells., PMID:36202057

Single-cell landscape and clinical outcomes of infiltrating B cells in colorectal cancer., PMID:36082430

CCL28 Enhances HSV-2 gB-Specific Th1-Polarized Immune Responses against Lethal Vaginal Challenge in Mice., PMID:36016177

Peripheral Blood Mononuclear Cells Predict Therapeutic Efficacy of Immunotherapy in NSCLC., PMID:35740564

Galactose-Deficient IgA1 B cells in the Circulation of IgA Nephropathy Patients Carry Preferentially Lambda Light Chains and Mucosal Homing Receptors., PMID:35115327

Immune B cell responsiveness to single-dose intradermal vaccination against Mycoplasma hyopneumoniae., PMID:34688042

Role of Th22 Cells in the Pathogenesis of Autoimmune Diseases., PMID:34295334

Antibody-mediated depletion of CCR10+EphA3+ cells ameliorates fibrosis in IPF., PMID:33945505

Vi-Vaccinations Induce Heterogeneous Plasma Cell Responses That Associate With Protection From Typhoid Fever., PMID:33424833

Development of a 43 color panel for the characterization of conventional and unconventional T-cell subsets, B cells, NK cells, monocytes, dendritic cells, and innate lymphoid cells using spectral flow cytometry., PMID:33336868

High CXCR3 on Leukemic Cells Distinguishes IgHV mut from IgHV unmut in Chronic Lymphocytic Leukemia: Evidence from CD5high and CD5low Clones., PMID:32802894

Coordinated co-migration of CCR10+ antibody-producing B cells with helper T cells for colonic homeostatic regulation., PMID:32773769

Transcriptomic Analysis of Spleen Revealed Mechanism of Dexamethasone-Induced Immune Suppression in Chicks., PMID:32384708

Intramuscular Immunization with Chemokine-Adjuvanted Inactive Porcine Epidemic Diarrhea Virus Induces Substantial Protection in Pigs., PMID:32102459

CCR10 expression is required for the adjuvant activity of the mucosal chemokine CCL28 when delivered in the context of an HIV-1 Env DNA vaccine., PMID:32057572

Evaluation of Lymphocyte Migration to Induced Paederus Dermatitis: An Experimental Study in Rats., PMID:31896838

CCL28 promotes locomotor recovery after spinal cord injury via recruiting regulatory T cells., PMID:31557129

Interferon as a Mucosal Adjuvant for an Influenza Vaccine in Pigs., PMID:30989429

CCL28 Is Involved in Mucosal IgA Responses, Olfaction, and Resistance to Enteric Infections., PMID:30855201

HCT-116 colorectal cancer cells secrete chemokines which induce chemoattraction and intracellular calcium mobilization in NK92 cells., PMID:30847498

Th22 Cells Promote Osteoclast Differentiation via Production of IL-22 in Rheumatoid Arthritis., PMID:30619268

Bufalin inhibits cell proliferation and migration of hepatocellular carcinoma cells via APOBEC3F induced intestinal immune network for IgA production signaling pathway., PMID:30100060

Cow's Milk and Immune Function in the Respiratory Tract: Potential Mechanisms., PMID:29483908

Oral cholera vaccination promotes homing of IgA+ memory B cells to the large intestine and the respiratory tract., PMID:29467446

The Human Penis Is a Genuine Immunological Effector Site., PMID:29312291

CCL28-Deficient Mice Have Reduced IgA Antibody-Secreting Cells and an Altered Microbiota in the Colon., PMID:29237777

Plasmablasts With a Mucosal Phenotype Contribute to Plasmacytosis in Systemic Lupus Erythematosus., PMID:28622453

Immunotherapy-induced sarcoidosis in patients with melanoma treated with PD-1 checkpoint inhibitors: Case series and immunophenotypic analysis., PMID:28480561

Glatiramer Acetate, Dimethyl Fumarate, and Monomethyl Fumarate Upregulate the Expression of CCR10 on the Surface of Natural Killer Cells and Enhance Their Chemotaxis and Cytotoxicity., PMID:27807435

Oral Vaccination with Attenuated Salmonella typhimurium-Delivered TsPmy DNA Vaccine Elicits Protective Immunity against Trichinella spiralis in BALB/c Mice., PMID:27589591

Co-delivery of GPI-anchored CCL28 and influenza HA in chimeric virus-like particles induces cross-protective immunity against H3N2 viruses., PMID:27178810

Chemokine receptor patterns in lymphocytes mirror metastatic spreading in melanoma., PMID:26854930

CCR6(+) Th cell populations distinguish ACPA positive from ACPA negative rheumatoid arthritis., PMID:26617177

Bovine CCL28 Mediates Chemotaxis via CCR10 and Demonstrates Direct Antimicrobial Activity against Mastitis Causing Bacteria., PMID:26359669

TSLP Directly Interacts with Skin-Homing Th2 Cells Highly Expressing its Receptor to Enhance IL-4 Production in Atopic Dermatitis., PMID:26288354

Th22 cells increase in poor prognosis multiple myeloma and promote tumor cell growth and survival., PMID:26155400

Chemokine-adjuvanted electroporated DNA vaccine induces substantial protection from simian immunodeficiency virus vaginal challenge., PMID:25943275

C-type lectin-like receptor LOX-1 promotes dendritic cell-mediated class-switched B cell responses., PMID:25308333

Ongoing activation of autoantigen-specific B cells in primary biliary cirrhosis., PMID:25043065

Generation of colonic IgA-secreting cells in the caecal patch., PMID:24718324

Preferential infiltration of interleukin-4-producing CXCR4+ T cells in the lesional muscle but not skin of patients with dermatomyositis., PMID:24580543

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