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Anti-MMP13 Antibody (R3L33)

Catalog #:   RHE45103 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: IHC
Accession: P45452
Overview

Catalog No.

RHE45103

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

IHC: 1:25-1:200

Target

MMP-13, MMP13, Matrix metalloproteinase-13, Collagenase 3

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P45452

Applications

IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3L33

Data Image
  • Immunohistochemical
    IHC-P analysis of breast tissue by MMP13 antibody (RHE45103). IHC-P was performed using sections of the formalin-fixed paraffin-embedded breast tissue;Result: Myoepithelial cells are positively stained at the cytoplasm.
References

Carpaine ameliorates synovial inflammation by promoting p65 degradation and inhibiting the NF-κB signalling pathway., PMID:40237708

Nanocellulose-modified electrodes for simultaneous biosensing of microbiome-related oral diseases biomarkers., PMID:39932508

Bifidobacterium animalis BD400 protects from collagen-induced arthritis through histidine metabolism., PMID:39911381

Protective effect of a combination of multiple strains of Lactobacillus acidophilus on collagen-induced arthritis., PMID:39807088

Celecoxib Combined with Tocilizumab Has Anti-Inflammatory Effects and Promotes the Recovery of Damaged Cartilage via the Nrf2/HO-1 Pathway In Vitro., PMID:39766343

Exploring Intra-Articular Administration of Monoclonal Antibodies as a Novel Approach to Osteoarthritis Treatment: A Systematic Review., PMID:39457530

Mapping RANKL- and OPG-expressing cells in bone tissue: the bone surface cells as activators of osteoclastogenesis and promoters of the denosumab rebound effect., PMID:39424806

The novel HSP90 monoclonal antibody 9B8 ameliorates articular cartilage degeneration by inhibiting glycolysis via the HIF-1 signaling pathway., PMID:39229534

Syndecan-4 inhibition attenuates cartilage degeneration in temporomandibular joint osteoarthritis., PMID:39101668

Lysosomal degradation of PD-L1 is associated with immune-related adverse events during anti-PD-L1 immunotherapy in NSCLC patients., PMID:38799168

Combinatory Nanovesicle with siRNA-Loaded Extracellular Vesicle and IGF-1 for Osteoarthritis Treatments., PMID:38791285

Evaluation of MMP-9, MMP-13, MMP-21, and TIMP-1 expressions in malign melanom, dysplastic nevi, and banal nevi., PMID:38757103

Protein kinase D drives the secretion of invasion mediators in triple-negative breast cancer cell lines., PMID:38323010

Macrophage expressed tartrate-resistant acid phosphatase 5 promotes pulmonary fibrosis progression., PMID:38178705

The role of EDIL3 in maintaining cartilage extracellular matrix and inhibiting osteoarthritis development., PMID:38081212

Anti-Inflammatory Effects of Boric Acid in Treating Knee Osteoarthritis: Biochemical and Histopathological Evaluation in Rat Model., PMID:37770671

Ganoderma lucidum polysaccharide peptide (GLPP) attenuates rheumatic arthritis in rats through inactivating NF-κB and MAPK signaling pathways., PMID:37586160

Angiopoietin-2 Promotes Mechanical Stress-induced Extracellular Matrix Degradation in Annulus Fibrosus Via the HIF-1α/NF-κB Signaling Pathway., PMID:37475697

Histopathological, biochemical and molecular studies on a model of systemic autoimmune disease induced by sodium silicate in non-genetically prone rats., PMID:37100362

MMP2 is a immunotherapy related biomarker and correlated with cancer-associated fibroblasts infiltrate in melanoma., PMID:36788565

Bevacizumab suppressed degenerative changes in articular cartilage explants from patients with osteoarthritis of the knee., PMID:36627659

Immune function modulation during artificial ovarian maturation in Japanese eel (Anguilla japonica): A transcriptome profiling approach., PMID:36341870

Tofacitinib Inhibits STAT Phosphorylation and Matrix Metalloproteinase-3, -9 and -13 Production by C28/I2 Human Juvenile Chondrocytes., PMID:36217356

Interleukin-6 neutralization and regulatory T cells are additive in chondroprotection from IL-1β-induced inflammation., PMID:36205183

IL-1 receptor antagonist (IL-1RA) suppresses a hyper-IL-17 response-mediated bone loss in a murine experimental periodontitis., PMID:36191445

Atorvastatin attenuates NS1 (Non-structural protein-1) of dengue type-2 serotype-induced expressions of matrix metalloproteinases in HL-60 cells, differentiated to neutrophils: Implications for the immunopathogenesis of dengue viral disease., PMID:36108401

Inhibition of HMGB1 suppresses inflammation and catabolism in temporomandibular joint osteoarthritis <em>via</em> NF-κB signaling pathway., PMID:35726537

Autologous hematopoietic stem cell transplantation promotes connective tissue remodeling in systemic sclerosis patients., PMID:35488348

Release of Matrix Metalloproteinases by Macrophages in Radicular Cysts and Residual Radicular Cysts., PMID:35384879

Mechanical Stimulation Protects Against Chondrocyte Pyroptosis Through Irisin-Induced Suppression of PI3K/Akt/NF-κB Signal Pathway in Osteoarthritis., PMID:35356271

Mechanotransductive Mechanisms of Biomimetic Hydrogel Cues Modulating Meckel's Cartilage Degeneration., PMID:35347898

Elevated MMP10/13 mediated barrier disruption and NF-κB activation aggravate colitis and colon tumorigenesis in both individual or full miR-148/152 family knockout mice., PMID:34979166

MEK1/2 Inhibitor (GDC0623) Promotes Osteogenic Differentiation of Primary Osteoblasts Inhibited by IL-1β through the MEK-Erk1/2 and Jak/Stat3 Pathways., PMID:34976051

KLF4, negatively regulated by miR-7, suppresses osteoarthritis development via activating TGF-β1 signaling., PMID:34891002

Monocytes secrete CXCL7 to promote breast cancer progression., PMID:34789744

IL-40: A New B Cell-Associated Cytokine Up-Regulated in Rheumatoid Arthritis Decreases Following the Rituximab Therapy and Correlates With Disease Activity, Autoantibodies, and NETosis., PMID:34745117

Evaluation of cytokines in protective effect of docosahexaenoic acid in experimental achilles tendinopathy rat model induced with type-1 collagenase., PMID:34612118

Amelioration of post-traumatic osteoarthritis via nanoparticle depots delivering small interfering RNA to damaged cartilage., PMID:34413494

A serological type II collagen neoepitope biomarker reflects cartilage breakdown in patients with osteoarthritis., PMID:36474766

Bevacizumab Arrests Osteoarthritis Progression in a Rabbit Model: A Dose-Escalation Study., PMID:34206900

Inhibition of sphingosine 1-phosphate protects mice against chondrocyte catabolism and osteoarthritis., PMID:34144150

Denosumab alleviates intervertebral disc degeneration adjacent to lumbar fusion by inhibiting endplate osteochondral remodeling and vertebral osteoporosis in ovariectomized rats., PMID:34049577

Adalimumab Induces a Wound Healing Profile in Patients with Hidradenitis Suppurativa by Regulating Macrophage Differentiation and Matrix Metalloproteinase Expression., PMID:33965402

Advanced oxidation protein products induce inflammatory responses and invasive behaviour in fibroblast-like synoviocytes via the RAGE-NF-κB pathway., PMID:33827262

Evaluation of CCL21 role in post-knee injury inflammation and early cartilage degeneration., PMID:33651836

Frugoside delays osteoarthritis progression via inhibiting miR-155-modulated synovial macrophage M1 polarization., PMID:33493345

Proinflammatory and bone protective role of calcitonin gene-related peptide alpha in collagen antibody-induced arthritis., PMID:33221885

Maltol prevents the progression of osteoarthritis by targeting PI3K/Akt/NF-κB pathway: In vitro and in vivo studies., PMID:33211383

Non-Canonical WNT5A Signaling Through RYK Contributes to Aggressive Phenotype of the Rheumatoid Fibroblast-Like Synoviocytes., PMID:33178184

Intervening upregulated SLC7A5 could mitigate inflammatory mediator by mTOR-P70S6K signal in rheumatoid arthritis synoviocytes., PMID:32867828

Datasheet

Document Download

Anti-MMP13 Antibody (R3L33).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-MMP13 Antibody (R3L33) [RHE45103]
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